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- ALCAM: CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins. In humans it is encoded by the ALCAM gene. It is also called CD166, MEMD, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. Some literature sources have also cited it as the CD6 ligand. It is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, neurons, melanoma cells, and also in sweat and sebaceous glands. CD166 protein expression is reported to be upregulated in a cell line deriving from a metastasizing melanoma. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker.
- Alcam a.k.a. activated leukocyte cell adhesion molecule is a gene.
- also known as activated leucocyte cell adhesion molecule
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According to news reporting originating from Heidelberg, Germany, by NewsRx correspondents, research stated, “ALCAM is a member of the cell adhesion molecule (CAM) family which plays an important role during nervous system formation.
Biosensors and Cancer (2012)
by Victor R. Preedy, Vinood Patel
ALCAM is a 105 kDa protein with a normal presence in human blood with evidence for being linked to multiple carcinomas (Ofori-Acquah and King 2008). Thus, a monoclonal antibody to ALCAM (anti-ALCAM) was used to determine the ...
Pediatric Bone (2003)
Biology & Diseases by John M. Pettifor, Harald Juppner
ALCAM is an immunoglobulin (Ig) superfamily ligand for CD6 antigen  that is present in lymphoid tissue and may be involved in homing of hemopoietic cells [ 91,92]. Nevertheless, ALCAM expression may be useful in combination with ...
dendritic cells JAM-A Ig-superfamily þ þ Blood endothelium Increased dendritic cell migration ALCAM Ig-superfamily (þ) þ Many cell types Impaired dendritic cell traffic VCAM-1 Ig-superfamily – þ Blood endothelium ICAM-1 Ig-superfamily ...
by Julius M. Cruse, Robert E. Lewis
activated leukocyte cell adhesion molecule (ALCAM/CD166) A member of the immunoglobulin (Ig) ...
Mongolian-English Dictionary (2013)
by Ferdinand D Lessing
ALCAM / AJIiiAM n. Big step. \ ALCANG / AIIHAH adj. Spread wide apart; bowlegged. ). ALCARXAI ALCARXAI / MHIAPXAFI , n. Summer ...
by John M. Lackie
leukocyte cell adhesion molecule A cell adhesion molecule (ALCAM, CD166, 583aa) of the immunoglobulin superfamily, the human homologue of chicken DM -GRASP.
A Dictionary of Biomedicine (2010)
by John Lackie
neurolin A cell surface glycoprotein (BEN, ALCAM, SCI, DM- GRASP, CD166, 500 aa) originally identified in goldfish and zebrafish as being involved ...
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Scrabble value of A1L1C3A1M3
The value of this 5-letter word is 9 points, but it's not an accepted word in the Official Scrabble Players Dictionary.
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