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  1. ALCAM: CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins. In humans it is encoded by the ALCAM gene. It is also called CD166, MEMD, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. Some literature sources have also cited it as the CD6 ligand. It is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, neurons, melanoma cells, and also in sweat and sebaceous glands. CD166 protein expression is reported to be upregulated in a cell line deriving from a metastasizing melanoma. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker.
  2. Alcam a.k.a. activated leukocyte cell adhesion molecule is a gene.
    • also known as activated leucocyte cell adhesion molecule

Printed dictionaries and other books with definitions for ALCAM

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Google previewCell Surface Extensions—Advances in Research and Application: 2013 Edition (2013)

According to news reporting originating from Heidelberg, Germany, by NewsRx correspondents, research stated, “ALCAM is a member of the cell adhesion molecule (CAM) family which plays an important role during nervous system formation.

Google previewBiosensors and Cancer (2012)

by Victor R. Preedy, Vinood Patel

ALCAM is a 105 kDa protein with a normal presence in human blood with evidence for being linked to multiple carcinomas (Ofori-Acquah and King 2008). Thus, a monoclonal antibody to ALCAM (anti-ALCAM) was used to determine the ...

Google previewPediatric Bone (2003)

Biology & Diseases by John M. Pettifor, Harald Juppner

ALCAM is an immunoglobulin (Ig) superfamily ligand for CD6 antigen [90] that is present in lymphoid tissue and may be involved in homing of hemopoietic cells [ 91,92]. Nevertheless, ALCAM expression may be useful in combination with ...

Google previewEncyclopedia of Immunobiology (2016)

dendritic cells JAM-A Ig-superfamily þ þ Blood endothelium Increased dendritic cell migration ALCAM Ig-superfamily (þ) þ Many cell types Impaired dendritic cell traffic VCAM-1 Ig-superfamily – þ Blood endothelium ICAM-1 Ig-superfamily ...

Google previewIllustrated Dictionary of Immunology, Third Edition (2009)

by Julius M. Cruse, Robert E. Lewis

activated leukocyte cell adhesion molecule (ALCAM/CD166) A member of the immunoglobulin (Ig) ...

Google previewMongolian-English Dictionary (2013)

by Ferdinand D Lessing

ALCAM / AJIiiAM n. Big step. \ ALCANG / AIIHAH adj. Spread wide apart; bowlegged. ). ALCARXAI ALCARXAI / MHIAPXAFI , n. Summer ...

Google previewThe Dictionary of Cell and Molecular Biology (2012)

by John M. Lackie

leukocyte cell adhesion molecule A cell adhesion molecule (ALCAM, CD166, 583aa) of the immunoglobulin superfamily, the human homologue of chicken DM -GRASP.

Google previewA Dictionary of Biomedicine (2010)

by John Lackie

neurolin A cell surface glycoprotein (BEN, ALCAM, SCI, DM- GRASP, CD166, 500 aa) originally identified in goldfish and zebrafish as being involved ...

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Scrabble value of A1L1C3A1M3

The value of this 5-letter word is 9 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

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