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Definition of the noun acantholysis
What does acantholysis mean as a name of something?
noun - plural: -
- a breakdown of a cell layer in the epidermis (as in pemphigus)
Alternative definition of the noun acantholysis
- [medicine] The loss of intercellular connections, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris.
Printed dictionaries and other books with definitions for Acantholysis
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by K. V.F. Jubb
Acantholysis is a loss of cohesion between epidermal cells resulting in intraepidermal clefts, vesicles, and bullae (Fig. 5.8). This process may also involve the outer root sheath of hair follicles and glandular ductal epithelium. Acantholysis is ...
Medicine, Internal medicine by CTI Reviews
Acantholysis is the loss of intercellular connections resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris. This histological feature is also seen in herpes simplex infections (HSV 1 and 2). Measles is ...
Practical Dermatopathology (2012)
by Ronald P. Rapini
Acantholysis Acantholysis is the loss of cohesion between keratinocytes as a result of dissolution of intercellular connections, sometimes resulting in an intraepidermal vesicle.
Clinical Dermatology by William D. James, Timothy Berger, Dirk Elston
Acantholysis is an uncommon finding but may be present. The inflammatory infiltrate in the dermis is composed of mononuclear cells and is generally mild. Specimens should be obtained from skin sites where hair follicles are numerous.
by David E. Elder, Rosalie Elenitsas, Bernett L. Johnson, George F. Murphy
Acantholysis is the most prominent feature. The pattern may resemble that of pemphigus vulgaris, pemphigus vegetans, pemphigus foliaceus, or benign familial pemphigus (45).Acantholysis may be combined with dyskeratosis, in which case ...
Part Two Studies in Major Organ Systems by K. D. Rainsford, G. P. Velo
Acantholysis is a typical though not pathognomonic histological abnormality of pemphigus that is also to be seen ...
A Pathologist's Survival Guide by Steven D. Billings, Jenny Cotton
Acantholysis is the result of loss of appropriate keratinocyte–keratinocyte adherence. This adherence is mediated by tight junctions, adherens junctions, gap junctions, and desmosomes. Desmosomes are critical to keratinocyte adhesion, and ...
by J. Reinert, H. Ursprung
Acantholysis is a condition, of multiple origin, in which the epidermis loses its compact histological structure and fluid spaces (blisters) appear. WILGRAM and CAULFIELD (1965) studying a variety of acantholytic diseases, reported graded ...
USMLE Images for the Boards (2012)
A Comprehensive Image-Based Review by Amber S. Tully, James S. Studdiford
Definitive diagnosis via punch biopsy □ Treatment with corticosteroids and immunosuppressive drugs □ Acantholysis is the breaking apart of epidermal cells. □ Both cutaneous and mucosal lesions □ Flaccid bullae □ Positive Nikolsky sign ...
Histology for Pathologists (2016)
Medicine, Internal medicine by CTI Reviews
Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris. It is absent in bullous pemphigoid, making it useful for differential ...
by Robert E. J. Ryder, M. Afzal Mir, E. Anne Freeman
Acantholysis is a characteristic histological feature. Nikolsky's sign* is invariably present. Immunofluorescence of biopsy shows intercellular immunoglobulins ( usually IgG) and/or complement factor C3. Pemphigoid: the site of the blisters is at ...
Medicine, Allergology by CTI Reviews
Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris.
by Jean L. Bolognia, Joseph L. Jorizzo, Julie V. Schaffer
acantholysis, ballooning degeneration. Acantholysis refers to discohesion of keratinocytes as a consequence of the disruption of desmosomes (intercellular connections) and this can lead to an ...
by Jonathan J. Dutton, Gregg S. Gayre, Alan D. Proia
Acantholysis is the loss of cohesion between epidermal (or epithelial) cells leading to the formation of intraepidermal clefts, vesicles, or bullae. Primary acantholysis results from dissolution or separation of the desmosomes ...
by Christopher Griffiths, Jonathan Barker, Tanya Bleiker, Robert Chalmers, Daniel Creamer
Acantholysis is the term used to describe a loss of cohesion between keratinocytes due to the break down of intercellular bridges. It results in the formation of intraepidermal clefts, vesicles and bullae. It appears to be the primary ...
by Susan B. Mallory
Histology: granular cell layer acantholysis DIF: IgG, C3 or both along keratinocyte surfaces Pemphìgus erythematosus SYN; seNEAR-usHER SYNDROME Clinical features of lupus erythematosus with lesions on face with erythema and scaling ...
by Joseph Segen
acantholysis. Dermatology The pathologic disruption of intercellular bridges between keratinocytes in the squamous epithelium of mucocutaneous surfaces, resulting in intraepithelial vesicles Diseases with Pemphigus vulgaris, benign familial ...
Encyclopedia of Cell Biology (2015)
These inhibit desmosomal adhesion causing loss of cell–cell adhesion ( acantholysis) that manifests as blistering of the skin and mucosae. One mechanism for these autoantibodies to disrupt adhesion is by inducing the downregulation of Dsg ...
A Dictionary of Medicine (1894)
Including General Pathology, General Therapeutics, Hygiene, and the Diseases of Women and Children by Sir Richard Quain
ACANTHOLYSIS. — An acanthosis characterized by separation of the upper layers of the epidermis — as pemphigus essentialis and gangrsena cachectica infantum. ACANTHOMA. — Hyperplasia of the prickle-cell layer of the epidermis.
by Chad A. Noggle, Arthur MacNeill Horton
Skin biopsy: histology shows keratinocyte necrosis, epidermal acantholysis, and IgG and complement deposition in epidermal and basement membrane Zones Cyclophosphamide ...
Acantholysis A. Pemphigus C Sub-epithelial vesicles B. Psoriasis D. Apusitzsign C Lichenplanus D. Erythema multiforme 314. Nikolsky's sign is positive ...
by Christopher Heath
Acantholysis, ii. 180 Acarus ...
by UN Panda
Acantholysis A term used in dermal pathology to denote dissolution of the layers of the epidermis. It is seen in such conditions as pemphigus vulgaris and keratosis follicularis. Acanthoma Well differentiated a. keratinizing cornifying squamous ...
A Dictionary of Dentistry (2010)
by Robert Ireland
acantholysis n. The breakdown of epidermal or epithelial cells due to a loss of intercellular substance . It is often seen in conditions such as *pemphigus vulgaris, where it is caused by ...
by Pei-Show Juo
Acantholysis Destruction of the epidermis. Acanthoma Carcinoma of the epidermis or tumor of the skin. Acanthosis The thickening and warty growth of the prickle-cell layer of the skin, e.g., eczema and psoriasis. Acapnia A marked decrease of ...
Mosby's Dictionary of Medicine, Nursing and Health Professions - Australian & New Zealand Edition (2014)
by Peter Harris, Sue Nagy, Nicholas Vardaxis
acantholysis /akމantholމisis/, loss of cohesion between keratinocytes, sometimes resulting in an intraepidermal blister. The cells are rounded.
by Lionel Fry, Fenella Wojnarowska, Parvin Shahrad
Histology will show an intraepidermal blister, and socalled acantholysis, in which the epidermal cells drift apart from each other, and the space between them becomes filled with fluid.
A medical dictionary written by a doctor for doctors, now illustrated by Joseph C Segen
Cf Bullous pemphigoid Pathology Acantholysis.
Encyclopedia of Toxicology (2005)
by Bruce Anderson, Ann de Peyster, Shayne C. Gad, P.J. Bert Hakkinen, Michael Kamrin, Betty Locey, Harihara M. Mehendale, Carey Pope, Lee Shugart
Following an oral gavage for 90 days, the noeffect dose is 8mgkg −1 day −1 , with severe forestomach tissue lesions characterized by inflammation, necrosis, acantholysis, hyperkeratosis, and epithelial hyperplasia. Mice exposed to 8ppm ...
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Scrabble value of A1C3A1N1T1H4O1L1Y4S1I1S1
The value of this 12-letter word is 20 points, but it's not an accepted word in the Official Scrabble Players Dictionary.
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