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Header of Acantholysis


Definition of the noun acantholysis

What does acantholysis mean as a name of something?

noun - plural: -

  1. a breakdown of a cell layer in the epidermis (as in pemphigus)
    • lexical domain: States - nouns denoting stable states of affairs
    • more generic terms: disease of the skin / skin disease / skin disorder = a disease affecting the skin
    • part of: pemphigus = a skin disease characterized by large thin-walled blisters (bullae) arising from normal skin or mucous membrane

Alternative definition of the noun acantholysis


  1. [medicine] The loss of intercellular connections, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris.

Printed dictionaries and other books with definitions for Acantholysis

Click on a title to look inside that book (if available):

Google previewPathology of Domestic Animals (2013)

by K. V.F. Jubb

Acantholysis is a loss of cohesion between epidermal cells resulting in intraepidermal clefts, vesicles, and bullae (Fig. 5.8). This process may also involve the outer root sheath of hair follicles and glandular ductal epithelium. Acantholysis is ...

Google previewPractical Dermatopathology (2012)

by Ronald P. Rapini

Acantholysis Acantholysis is the loss of cohesion between keratinocytes as a result of dissolution of intercellular connections, sometimes resulting in an intraepidermal vesicle.

Google previewLever's Histopathology of the Skin (2009)

by David E. Elder, Rosalie Elenitsas, Bernett L. Johnson, George F. Murphy

Acantholysis is the most prominent feature. The pattern may resemble that of pemphigus vulgaris, pemphigus vegetans, pemphigus foliaceus, or benign familial pemphigus (45).Acantholysis may be combined with dyskeratosis, in which case ...

Google previewSide-Effects of Anti-Inflammatory Drugs (2012)

Part Two Studies in Major Organ Systems by K. D. Rainsford, G. P. Velo

Acantholysis is a typical though not pathognomonic histological abnormality of pemphigus that is also to be seen in ...

Google previewInflammatory Dermatopathology (2010)

A Pathologist's Survival Guide by Steven D. Billings, Jenny Cotton

Acantholysis is the result of loss of appropriate keratinocyte–keratinocyte adherence. This adherence is mediated by tight junctions, adherens junctions, gap junctions, and desmosomes. Desmosomes are critical to keratinocyte adhesion, and ...

Google previewOrigin and Continuity of Cell Organelles (2013)

by J. Reinert, H. Ursprung

Acantholysis is a condition, of multiple origin, in which the epidermis loses its compact histological structure and fluid spaces (blisters) appear. WILGRAM and CAULFIELD (1965) studying a variety of acantholytic diseases, reported graded ...

Google previewe-Study Guide for: Oral Pathology: Clinical Pathologic Correlations (2012)

Medicine, Internal medicine by Cram101 Textbook Reviews

Acantholysis: Acantholysis is the loss of intercellular connections resulting in loss of cohesion between keratinocytes, seenin diseases such as pemphigus vulgaris . This histological feature is also seen in herpes simplex infections (HSV 1 and ...

Google previewe-Study Guide for Histology for Pathologists, textbook by Stacey E Mills (2013)

Medicine, Internal medicine by Cram101 Textbook Reviews

acantholysis: Acantholysis is the loss of intercellular connections, such as desmosomes, ...

Google previewUSMLE Images for the Boards (2012)

A Comprehensive Image-Based Review by Amber S. Tully, James S. Studdiford

Definitive diagnosis via punch biopsy □ Treatment with corticosteroids and immunosuppressive drugs □ Acantholysis is the breaking apart of epidermal cells. □ Both cutaneous and mucosal lesions □ Flaccid bullae □ Positive Nikolsky sign ...

Google previewAn Aid to the MRCP Short Cases (2009)

by Robert E. J. Ryder, M. Afzal Mir, E. Anne Freeman

Acantholysis is a characteristic histological feature. Nikolsky's sign* is invariably present. Immunofluorescence of biopsy shows intercellular immunoglobulins ( usually IgG) and/or complement factor C3. Pemphigoid: the site of the blisters is at ...

Google previewEdinburgh Medical Journal (1906)

While acantholysis is a condition precedent to almost all bullous diseases, ...

Google previewDermatopathology (2012)

by C.L. Berry

Acantholysis is a recognised feature of dermatitis herpetiformis, but is nota primary cause of blister formation. The acantholytic cells are seen either as single cells or in clumps, and are only seen in vesiclesor bullae in which polymorphs are ...

Google previewDiagnostic Atlas of Common Eyelid Diseases (2007)

by Jonathan J. Dutton, Gregg S. Gayre, Alan D. Proia

Acantholysis is the loss of cohesion between epidermal (or epithelial) cells leading to the formation of intraepidermal clefts, vesicles, or bullae. Primary acantholysis results from dissolution or separation of the desmosomes ...

Google previewThe American Illustrated Medical Dictionary (1916)

acantholysis (ak-an-tholis-is) (Gr. 5xav6a ...

Google previewA Dictionary of Medicine (1894)

Including General Pathology, General Therapeutics, Hygiene, and the Diseases of Women and Children by Sir Richard Quain

ACANTHOLYSIS. — An acanthosis characterized by separation of the upper layers of the epidermis — as pemphigus essentialis and gangrsena cachectica infantum. ACANTHOMA. — Hyperplasia of the prickle-cell layer of the epidermis.

Google previewDictionary of Practical Surgery (1886)

by Christopher Heath

Acantholysis, ii. 180 Acarus ...

Google previewA dictionary of medical science ... (1903)

by Robley Dunglison

bullo 'sa, acantholysis bullosa. Epider'mophyte (epidermis +phylon, vegetable) . Vegetable parasite of the skin. Epidermoph yton. Microsporon furfur. E. galli'- nse, fungus like Achorion schoenleinii, producing favus in fowls. Epider'mose.

Google previewThe Practitioner's Medical Dictionary (1919)

Containing All the Words and Phrases Generally Used in Medicine and the Allied Sciences, with Their Proper Pronunciation, Derivation, and Definition by George Milbry Gould, Richard John Ernst Scott

acantholysis (ak-an-thol'-is-is) [axavBa., prickle; Xfott, a loosening, a wasting]. Any skin disease in which there is an atrophy of the prickle-layer, u. bullosa, see epidermolysis. acanthoma (ak-an-tho' ...

Google previewA practical medical dictionary ... (1914)

by Thomas Lathrop Stedman

acantholysis bullosa ; a condition of the skin, hereditary in origin, in which large bulla; are produced by slight mechanical irritation. Epldermoph'yton [epidermis + G. phyton, plant.] A genus of fungi, separated by Sabouraud from Trichophyton ...

Google previewAn Illustrated Dictionary of Medicine, Biology and Allied Sciences, Including the Pronunciation... (1903)

by George Milbry Gould

Acantholysis (a/e~an-t/zol/-zs- z's) ...

Google previewLippincott's New Medical Dictionary (1910)

A Vocabulary of the Terms Used in Medicine, and the Allied Sciences, with Their Pronunciation, Etymology, and Signification, Including Much Collateral Information of a Descriptive and Encyclopedic Character by Henry Ware Cattell

= Acantholysis.

Google previewThe American illustrated medical dictionary. 1916 |8th ed. 1916 printing (1919)

acantholysis (ak-an-thol'is-is) [Gr. ixarBa prickle + \bots a loosening). Atrophy and detachment of the prickle layer of the skin (Auspitz). acanthoma (ak-an-tho' mah), pi. acanthi) 'mala [(Jr. hnavBa prickle + o/io tumor]. A tumor or excessive ...

Google previewAn Illustrated Encyclopaedic Medical Dictionary (1890)


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Scrabble value of A1C3A1N1T1H4O1L1Y4S1I1S1

The value of this 12-letter word is 20 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

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