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Header of Acetylation


Definition of the noun acetylation

What does acetylation mean as a name of something?

noun - plural: acetylations

  1. the process of introducing an acetyl group into a compound
    • example: the acetylation of cyclooxygenase-2 by aspirin
    • lexical domain: Natural Processes - nouns denoting natural processes
    • more generic word: acylation = the process of introducing an acyl group into a compound

Alternative definition of the noun acetylation


  1. [chemistry] The reaction of a substance with acetic acid or one of its derivatives; the introduction of one or more acetyl groups into a substance

Printed dictionaries and other books with definitions for Acetylation

Click on a title to look inside that book (if available):

Google previewNucleoproteins—Advances in Research and Application: 2013 Edition (2013)

Histone acetylation is a fundamental mechanism involved in epigenetic regulation of gene expression and has been implicated in memory consolidation. ” Our news journalists obtained a quote from the research from the University of Buenos ...

Google previewTranscription Factors CREB and NF-Kb (2012)

Involvement in Synaptic Plasticity and Memory Formation by Benedict C. Albensi

Histone acetylation is a post-translational modification of chromatin being one of the epigenetic mechanisms for long-lasting regulation of gene expression. The initial step in gene-transcription activation involves recognition of the promoter ...

Google previewThe Developing Genome (2015)

An Introduction to Behavioral Epigenetics by David S. Moore

Histone acetylation is a process in which an acetyl group physically attaches to a histone (similar to how histone methylation involves a methyl group attaching to a histone). Histone acetylation and DNA methylation essentially have opposite ...

Google previewCardiac Energy Metabolism in Health and Disease (2014)

by Gary D. Lopaschuk, Ph.D., Naranjan S. Dhalla

Acetylation Control of Cardiac Fatty Acid Oxidation in Insulin Resistance and Diabetes Protein acetylation is an important dynamic/reversible post-translational modification involved in many cellular processes, including nuclear ...

Google previewMechanisms of Histone Acetyltransferases (2008)

by Christopher E. Berndsen

Acetylation is the function of proteins known as Histone Acetyltransferases (HATs ). These proteins occur in large multi-subunit complexes, however the mechanism of acetyl-transfer, nucleosome recognition, and the effects of the subunits on ...

Google previewN-lysine Acylation and Control of Coenzyme a Homeostasis in Salmonella Enterica (2008)

by Jane O. Garrity

INTRODUCTION Protein acetylation is a ubiquitous means for the rapid control of diverse cellular processes (11, 52). Acetylation occurs at lysine residues, with Ac- CoA serving as the acetyl group donor. In higher organisms, aberrant ...

Google previewPharmacology (2004)

Drug Actions and Reactions by Carol T. Walsh, Rochelle D. Schwartz-Bloom

Acetylation is the major pathway of elimination of isoniazid; slow inactivators have been found to possess a reduced quantity of the enzyme, N- acetyltransferase, which acetylates the drug. In this case, then, the genetic abnormality is a ...

Google previewSmith and Williams' Introduction to the Principles of Drug Design and Action, Fourth Edition (2005)

by H. John Smith, Hywel Williams

Acetylation is the primary metabolic pathway occurring for sulfonamides for example. Sulfate conjugation is the reaction between phenolic or alcoholic groups and inorganic sulfate, partially derived from sulfur-containing amino acids , e.g., ...

Google previewCereal Straw as a Resource for Sustainable Biomaterials and Biofuels (2010)

Chemistry, Extractives, Lignins, Hemicelluloses and Cellulose by RunCang Sun

Pyridine-catalyzed acetylation is a standard method for the determination of hydroxyl compounds and other acylable substances. The mechanism involves a nucleophilic catalyst with the intermediate formation of the acylpyridium ion [45].

Google previewLymphomas (2012)

Particularly, abnormal histone acetylation is a target of therapy, as it can be reversed by deacetylase inhibitors. Deacetylase inhibitors can also modify the acetylation status of a wide range of protein targets resulting in enhanced New ...

Google previewColon Cancer: New Insights for the Healthcare Professional: 2011 Edition (2012)

-dependent histone acetylation is an important mechanism of the regulation of cancer-related genes and inhibition of HDACs induces epithelial differentiation and decreased invasion. Therefore, in this study, we ...

Google previewDNA Methylation and Cancer Therapy (2005)

by Moshe Szyf

Since histone acetylation is the change observed in all cases, it most probably precedes hypermethylation, which seems to be a response to the inactive state of chromatin. DNMT1 and DNMT3b were shown to associate with both HDAC1 and ...

Google previewPharmacology - An Illustrated Review (2011)

by Mark A. Simmons

Slow acetylation is a recessive trait. The phenotype determines the rate of N- acetylation of drugs such as isoniazid and sulfonamides. Drug-induced lupus erythematous is more common in slow acetylators following exposure to hydralazine ...

Google previewThe Epigenetics Revolution (2011)

How Modern Biology is Rewriting our Understanding of Genetics, Disease and Inheritance by Nessa Carey

Like DNA methylation, lysine acetylation is an epigenetic mechanism for altering gene expression which doesn't change the underlying gene sequence. Figure 4.4 The chemical structures of the amino acid lysine and its epigenetically ...

Google previewRheumatology (2014)

by Marc C. Hochberg, Alan J. Silman, Josef S. Smolen, Michael E. Weinblatt, Michael H. Weisman

103,104 Since acetylation is a rather transient histone modification that responds rapidly to environmental ...

Google previewPrinciples of Bone Biology (2008)

Two-Volume Set by John P. Bilezikian, Lawrence G. Raisz, T. John Martin

Histone acetylation is a marker of the transcriptionally active chromatin structure, and transcriptional coactivators such as CBP and PCAF have histone acetylase activity (de la Serna et al., 2006; Ansel et al., 2006). Investigation of the ...

Google previewEncyclopedia of Molecular Pharmacology

by Stefan Offermanns

Berlin, Germany Synonyms Lysine acetylation of histones Definition >• Histone acetylation is a reversible and covalent modification of histone proteins introduced at the ...

Google previewEncyclopedia of Biological Chemistry (2013)

Histone acetylation involves the transfer of an acetyl moiety from acetyl-CoA to the e-amino group of a lysine residue, resulting in neutralization of the positive charge. Yeast Gcn5 was the first nuclear acetyltransferase to be identified, and ...

Google previewEncyclopedia of Genetics, Genomics, Proteomics, and Informatics (2008)

by George P. Rédei

Acetyl group Acetylation: Acetylation of histones opens the nucleosomal structure for transcription of the DNA.

Google previewThe Dictionary of Genomics, Transcriptomics and Proteomics (2015)

by Günter Kahl

Histone acetylation code 979 and serve to package nuclear DNA into the → nucleosomes of eukaryotic → chromatin. Histones interact with the negatively charged phosphate backbone of DNA via salt bridges. Within a nucleosome, histones ...

Google previewEncyclopedia of Behavioral Neuroscience, Three-Volume Set, 1- 3 (2010)

Histone acetylation is only one of collection of epigenetic marks that includes histone phosphorylation, methylation, sumoylation, ubiquitination, as well as DNA methylation. DNA methylation represses transcription through direct disruption of ...

Google previewA Dictionary of Biomedicine (2010)

by John Lackie

histone acetylation The post-translational modification of histones by histone acetyl ...

Google previewEncyclopedia of Psychopharmacology (2010)

by Ian Stolerman

Histone acetylation (A) is associated with chromatin relaxation and the binding of TFs and coactivators, such as HATs (histone acetyl transferases) and SWI-SNF proteins that mediate the movement of histone complexes along a strand of DNA.

Google previewSaunders Comprehensive Veterinary Dictionary (2011)

by Virginia P. Studdert, Clive C. Gay, Douglas C. Blood

acetylation [ -set′′ -la'sh n] one of the synthetic biotransformations whichoperateinthe metabolism of drugs in which metabolites areproducedthat are more readily excretedthanthe parent drug. Dogsare ...

Google previewThe Encyclopedia of Natural Medicine Third Edition (2012)

by Michael T. Murray, Joseph Pizzorno

Glutathione, vitamin B6 Methylation S-adenosyl-methionine Sulfation Cysteine, methionine, molybdenum Acetylation Acetyl coenzyme A Deficiency of folic acid or vitamin B12 Nonsteroidal anti-inflammatory drugs. Foods in the brassica family ...

Google previewEncyclopedia of Microbiology, Four-Volume Set (2000)

by Martin Alexander, Barry R. Bloom, David A. Hopwood, Roger Hull, Barbara H. Iglewski, Allen I. Laskin, Stephen G. Oliver, Moselio Schaechter, William C. Summers

acetylation) as well as monomer composition and its sequence . Through the judicious use of bacteria it should be possible to control all these ...

Google previewEncyclopedia of Applied Plant Sciences, Three-Volume Set (2003)

by Denis J Murphy, Brian G Murray

There isa strong correlation betweenhistone acetylation patterns and geneactivity . Heterochromatin isrich in nonacetylated histones,and thismay facilitate the sequestration of DNA into amore condensed and inaccessible packaging state.

Google previewEncyclopedia of Polymer Science and Technology, Concise (2013)

by Herman F. Mark

The reaction course is controlled by the rates of diffusion of the reagents into the cellulose fibers, and therefore the cellulose must be swollen or activated before acetylation to achieve uniform reaction and avoid unreacted fibers in the solution.

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Video about Acetylation

Acetylation Meaning

Video shows what acetylation means. The reaction of a substance with acetic acid or one of its derivatives, the introduction of one or more acetyl groups into a ...

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Scrabble value of A1C3E1T1Y4L1A1T1I1O1N1

The value of this 11-letter word is 16 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

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