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Header of Acetylation


Definition of the noun acetylation

What does acetylation mean as a name of something?

noun - plural: acetylations

  1. the process of introducing an acetyl group into a compound
    • example: the acetylation of cyclooxygenase-2 by aspirin
    • lexical domain: Natural Processes - nouns denoting natural processes
    • more generic word: acylation = the process of introducing an acyl group into a compound

Alternative definition of the noun acetylation


  1. [chemistry] The reaction of a substance with acetic acid or one of its derivatives; the introduction of one or more acetyl groups into a substance

Printed dictionaries and other books with definitions for Acetylation

Click on a title to look inside that book (if available):

Google previewPI3K-mTOR in Cancer and Cancer Therapy (2016)

by Nandini Dey, Pradip De, Brian Leyland-Jones

Protein acetylation is a critical posttranslation modification in the regulation of various cellular processes. Analogous to phosphorylation, acetylation can modify protein function and interactions. Histone acetylation is the most common example ...

Google previewApoptosis in Carcinogenesis and Chemotherapy (2009)

Apoptosis in cancer by George G. Chen, Paul B. S. Lai

However, the demonstration that DNA methylation is dependent on histone methylation or histone acetylation is the converse to...

In contrast, gene silencing by histone acetylation is a reversible process, which can be accomplished by the ...

Google previewPharmacology (2004)

Drug Actions and Reactions by Carol T. Walsh, Rochelle D. Schwartz-Bloom

Acetylation is the major pathway of elimination of isoniazid; slow inactivators have been found to possess a reduced quantity of the enzyme, N- acetyltransferase, which acetylates the drug. In this case, then, the genetic abnormality is a ...

Google previewCereal Straw as a Resource for Sustainable Biomaterials and Biofuels (2010)

Chemistry, Extractives, Lignins, Hemicelluloses and Cellulose by RunCang Sun

Pyridine-catalyzed acetylation is a standard method for the determination of hydroxyl compounds and other acylable substances. The mechanism involves a nucleophilic catalyst with the intermediate formation of the acylpyridium ion [45].

Google previewNucleoproteins—Advances in Research and Application: 2013 Edition (2013)

Histone acetylation is a fundamental mechanism involved in epigenetic regulation of gene expression and has been implicated in memory consolidation. ” Our news journalists obtained a quote from the research from the University of Buenos ...

Google previewClinical Pharmacology (2007)

With STUDENTCONSULT Access by Peter N. Bennett, Morris J. Brown

Acetylation is an important route of metabolism for 38A danger described by the Greek philosopher Pythagoras (570–495 BC) in perhaps the first recognition of an intermany drugs that possess an amide (–NH2) group. individual difference in ...

Google previewTranscription Factors CREB and NF-Kb (2012)

Involvement in Synaptic Plasticity and Memory Formation by Benedict C. Albensi

Histone acetylation is a post-translational modification of chromatin being one of the epigenetic mechanisms for long-lasting regulation of gene expression. The initial step in gene-transcription activation involves recognition of the promoter ...

Google previewMolecular and Quantitative Animal Genetics (2014)

by Hasan Khatib

Discovering how the epigenomic landscape is modified by butyrate-induced histone acetylation is a critical step in the path to understanding how this nutrient affects specific transcriptome changes at the mechanistic level.

Google previewThe Developing Genome (2015)

An Introduction to Behavioral Epigenetics by David S. Moore

Histone acetylation is a process in which an acetyl group physically attaches to a histone (similar to how histone methylation involves a methyl group attaching to a histone). Histone acetylation and DNA methylation essentially have opposite ...

Google previewCardiac Energy Metabolism in Health and Disease (2014)

by Gary D. Lopaschuk, Ph.D., Naranjan S. Dhalla

Acetylation Control of Cardiac Fatty Acid Oxidation in Insulin Resistance and Diabetes Protein acetylation is an important dynamic/reversible post-translational modification involved in many cellular processes, including nuclear ...

Google previewThe Molecular Basis for the Link Between Maternal Health and the Origin of Fetal Congenital Abnormalities (2011)

An Overview of Association with Oxidative Stress by Bashir M. Matata, Maqsood M. Elahi

Histone acetylation is the mostly studied epigenetic regulation. Histone deacetylase (HDAC) deacetylates histones and induce ...

Google previewCurrent Topics in Developmental Biology (2016)

Biology, Biology by CTI Reviews

Specifically, acetylation refers to the process of introducing an acetyl group ( resulting in an acetoxy group) into a compound, namely, the substitution of an acetyl group for an active hydrogen atom. Acetyltransferase is a type of transferase ...

Google previewMammalian Brain Development (2009)

by Damir Janigro

Thus, H3K9 acetylation is a marker of active gene transcription. ChIP assays using the same tissue ...

Google previewLymphomas (2012)

Particularly, abnormal histone acetylation is a target of therapy, as it can be reversed by deacetylase inhibitors. Deacetylase inhibitors can also modify the acetylation status of a wide range of protein targets resulting in enhanced New ...

Google previewColon Cancer: New Insights for the Healthcare Professional: 2011 Edition (2012)

-dependent histone acetylation is an important mechanism of the regulation of cancer-related genes and inhibition of HDACs induces epithelial differentiation and decreased invasion. Therefore, in this study, we ...

Google previewEncyclopedia of Molecular Pharmacology

by Stefan Offermanns

Berlin, Germany Synonyms Lysine acetylation of histones Definition >• Histone acetylation is a reversible and covalent modification of histone proteins introduced at the ...

Google previewEncyclopedia of Biological Chemistry (2013)

Histone acetylation involves the transfer of an acetyl moiety from acetyl-CoA to the e-amino group of a lysine residue, resulting in neutralization of the positive charge. Yeast Gcn5 was the first nuclear acetyltransferase to be identified, and ...

Google previewThe Dictionary of Genomics, Transcriptomics and Proteomics (2015)

by Günter Kahl

Histone acetylation code 979 and serve to package nuclear DNA into the → nucleosomes of eukaryotic → chromatin. Histones interact with the negatively charged phosphate backbone of DNA via salt bridges. Within a nucleosome, histones ...

Google previewA Dictionary of Biomedicine (2010)

by John Lackie

histone acetylation The post-translational modification of histones by histone acetyl ...

Google previewEncyclopedia of Cell Biology (2015)

Acetylation has been well described as a posttranslational event that regulates histones and protein translation with precision, but p53 was the first nonhistone protein shown to be acetylated as well (Gu and Roeder, 1997).

Google previewEncyclopedia of Behavioral Neuroscience (2010)

For example, it was found that chronic, but not acute, cocaine administration induces histone acetylation at the Cdk5 gene promoter in the NAcc. This is consistent with earlier observations that cocaine induces Cdk5 expression in this brain ...

Google previewEncyclopedia of Psychopharmacology (2010)

by Ian Stolerman

Histone acetylation (A) is associated with chromatin relaxation and the binding of TFs and coactivators, such as HATs (histone acetyl transferases) and SWI-SNF proteins that mediate the movement of histone complexes along a strand of DNA.

Google previewDictionary of Toxicology (2014)

by Ernest Hodgson, Michael Roe

Subsequent phase II reactions, sulfate ester formation, acetylation, and glucuronidation can also yield reactive metabolites that can react with nucleophilic substituents on nucleic acids and proteins. Adducts of N-2- acetylaminofluorene ...

Google previewEncyclopedia of Applied Plant Sciences (2016)

The acetylation of lysine residues on the core histones may reduce the affinity of histones for DNA and result in a loose form of association that is compatible with transcription. Alternatively, or additionally, it is possible that the function of ...

Google previewEncyclopedia of Microbiology, Four-Volume Set (2000)

by Martin Alexander, Barry R. Bloom, David A. Hopwood, Roger Hull, Barbara H. Iglewski, Allen I. Laskin, Stephen G. Oliver, Moselio Schaechter, William C. Summers

acetylation) as well as monomer composition and its sequence . Through the judicious use of bacteria it should be possible to control all these ...

Google previewEncyclopedia of Polymer Science and Technology, Concise (2013)

by Herman F. Mark

The reaction course is controlled by the rates of diffusion of the reagents into the cellulose fibers, and therefore the cellulose must be swollen or activated before acetylation to achieve uniform reaction and avoid unreacted fibers in the solution.

Google previewThe Encyclopedia of Natural Medicine Third Edition (2012)

by Michael T. Murray, Joseph Pizzorno

Glutathione, vitamin B6 Methylation S-adenosyl-methionine Sulfation Cysteine, methionine, molybdenum Acetylation Acetyl coenzyme A Deficiency of folic acid or vitamin B12 Nonsteroidal anti-inflammatory drugs. Foods in the brassica family ...

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Video about Acetylation

Acetylation Meaning

Video shows what acetylation means. The reaction of a substance with acetic acid or one of its derivatives, the introduction of one or more acetyl groups into a ...

See also the pronunciation examples of Acetylation!

Scrabble value of A1C3E1T1Y4L1A1T1I1O1N1

The value of this 11-letter word is 16 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

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