For all your dictionary needs!
Spelling. Are you looking for Acyclovir?
Header of Aciclovir



Aciclovir: A synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses. After conversion in vivo to the active metabolite acyclovir triphosphate, acyclovir competitively inhibits viral DNA polymerase, incorporates into and terminates the growing viral DNA chain, and inactivates viral DNA polymerase. The greater antiviral activity of acyclovir against HSV compared to VZV is due to its more efficient phosphorylation by the thymidine kinase of HSV.

  • also known as Acyclovir, Acycloguanosine

Printed dictionaries and other books with definitions for Aciclovir

Click on a title to look inside that book (if available):

Google previewFundamentals of Pharmacology (2015)

An Applied Approach for Nursing and Health by Alan Galbraith, Shane Bullock, Elizabeth Manias, Barry Hunt, Ann Richards

Resistance to aciclovir is an emergent cause of con- cern; this may also eventuate with famciclovir. Resistant cases can be treated with foscarnet (see below). Oral ganciclovir must be taken with or after food to maximise absorption. This drug ...

Google previewCrash Course: Cell Biology and Genetics (2013)

by Matthew Stubbs, Narin Suleyman

DNA polymerase inhibitors Aciclovir is an acyclic nucleoside analogue that acts as a chain terminator of herpesvirus DNA synthesis. It is a prodrug, converted to aciclovir monophosphate by a-herpesvirus encoded thymidine kinase.

Google previewOxford Handbook of Clinical Pathology (2012)

by James Carton

Aciclovir is a guanosine analogue which is phosphorylated by viral thymidine kinase. Aciclovir triphosphate is incorporated into viral DNA and terminates chain replication. • Ganciclovir is related to acyclovir, but is more active against ...

Google previewOphthalmic Surgery: Principles and Practice (2011)

by George L. Spaeth, Helen Danesh-Meyer, Ivan Goldberg, Anselm Kampik

Aciclovir is an anti-viral that is effective against the herpes family of viruses. It becomes activated in virus-infected cells by a virally encoded enzyme and is therefore non-toxic to uninfected cells. Ganciclovir is a nuceloside analog of aciclovir ...

Google previewOral and Maxillofacial Surgery (2012)

by Lars Andersson, Karl-Erik Kahnberg, M. Anthony Pogrel

Aciclovir is an acyclic guanine nucleoside analog drug. Many generic forms of aciclovir are currently available. It is one of the most commonly used antiviral drugs and has been primarily used for the treatment of herpes simplex virus and ...

Google previewInfectious Disease, eTextbook (2010)

Clinical Cases Uncovered by Hamish McKenzie, Robert Laing, Alexander Mackenzie, Pamela Molyneaux, Abhijit Bal

Aciclovir is a nucleoside analogue that ...

Google previewABC of Dermatology (2014)

by Rachael Morris-Jones

Aciclovir is a well-established antiviral drug used in the treatment of HHV. It inhibits viral DNA polymerase and irreversibly inhibits viral DNA synthesis. The underlying diagnosis determines the dose and treatment duration. Primary genital ...

Google previewQuestions and Answers for Dental Nurses (2013)

by Carole Hollins

caries Aciclovir is a drug used ...

Google previewMolecular Medicine (2016)

An Introduction by Jens Kurreck, Cy Aaron Stein

Aciclovir is a prodrug that is initially administered in an inactive form and is then metabolized into the active species in the body. Following selective first phosphorylation by the viral thymidine kinase, cellular kinases further phosphorylate the ...

Google previewBlack's Student Medical Dictionary (2015)

by Harvey Marcovitch

Aciclovir is an antiviral drug that inhibits DNA synthesis in cells infected by HERPES VIRUSES, although it does not eradicate them. It is only effective if started at the onset of infection; uses include the systemic treatment of herpes ...

Google previewBlack's Medical Dictionary (2005)

by Bloomsbury Publishing

Aciclovir is an antiviral drug that inhibits DNA synthesis in cells infected by HERPES VIRUSES, although it does not eradicate them. It is only effective if started at the onset of infection; uses include the systemic treatment of herpes simplex ...

Google previewConcise Medical Dictionary (2015)

by Elizabeth Martin

aciclovir. (acyclovir) n. an antiviral drug that inhibits DNA synthesis in cells infected by *herpesviruses. Administered ...

Google previewConcise Dictionary of Pharmacological Agents (1999)

Properties and Synonyms by Dr. Ian Morton, I.K. Morton, Judith M. Hall

aciclovir (BAN, INN.JAN] (acyclovir (usAN]: acyclovir sodium Iusan]: Zovirax") is a synthetic nucleoside analogue ANTIviRAL. It can be used orally or topically to treat infection by the herpesviruses, and is valuable in ...

Google previewA Dictionary of Biomedicine (2010)

by John Lackie

See ACICLOVIR. 2. Ot—AIIllIlO— adipylcysteinylvaline, a precursor for isopenicillin synthesis. acyclovir See ACICLOVIR. acyl An organic radical or functional group derived from an organic acid. Common examples are formyl, acetyl, ...

Google previewDictionary of Obstetrics and Gynecology (1988)

by Christoph Zink

2–OH NH3 N Aciclovir (INN) adaptation, maternal: the physiological adaptation processes of the maternal organism during pregnancy. 1. organic changes (usually hormonally mediated): genitalia: increased size of the uterus ...

Google previewThe Dictionary of Cell and Molecular Biology (2012)

by John M. Lackie

Aciclovir. (2) Alpha-aminoadipylcysteinylvaline, precursor for isopenicillin synthesis. ACV synthase Enzyme (alpha-aminoadipylcysteinyl- valine synthase, EC, 3770aa in Emericella nidulans) responsible for an early step in ...

Google previewDictionary of Optometry and Visual Science (2014)

by Michel Millodot

aciclovir See antiviral agents. acinar cell See cell, acinar. acidosis An abnormal condition character- ized by an increase in acidity and a relative decrease ...

Google previewChurchill Livingstone Medical Dictionary (2008)

by Chris Brooker


Google previewA Dictionary of Dentistry (2010)

by Robert Ireland

acellular acesulfamepotassium acetate strip acetone acetylsalicylic acid ache acheilia achlorhydria achondroplasia aciclovir acid acidetch technique acidogenic acidogenic theory acidosis acidulated phosphate fluoride gel aciduric acinic cell ...

Google previewThe Dictionary of Drugs: Chemical Data (2014)

Chemical Data, Structures and Bibliographies by J. Elks

Aciclovir, INN. Acycloguanosine. Cycloviran. Milavir.

Google previewSaunders Comprehensive Veterinary Dictionary (2011)

by Virginia P. Studdert, Clive C. Gay, Douglas C. Blood

acyclovir, aciclovir [a-si'klo-vēr] a synthetic analog of guanosine which selectively interferes with viral DNA synthesis. Usedparenterally and topicallyasan antiviral agent, butmore effective compounds are available for treatment ofherpetic ...

Google previewBailliere's Midwives' Dictionary (2012)

by Denise Tiran

acyclovir See aciclovir. adactylia, adactyly ...

Google previewA Dictionary of Biology (2015)

by Elizabeth Martin, Robert Hine

acyclovir See aciclovir. adaptation 1. (in evolution) Any change in the structure or functioning of successive generations of a population that makes it better suited to its environment. *Natural selection of heritable adaptations ultimately leads ...

Online dictionaries and encyclopedias with entries for Aciclovir

Click on a label to prioritize search results according to that topic:

Scrabble value of A1C3I1C3L1O1V4I1R1

The value of this 9-letter word is 16 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

Share this page


Go to the wordplay of Aciclovir for some fun with words!

Privacy Policy | Cookies Policy
Keyword Tool | Romanian-English Dictionary