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Adrenocortical carcinoma


Adrenocortical carcinoma, also adrenal cortical carcinoma and adrenal cortex cancer, is an aggressive cancer originating in the cortex of the adrenal gland. Adrenocortical carcinoma is a rare tumor, with incidence of 1–2 per million population annually. Adrenocortical carcinoma has a bimodal distribution by age, with cases clustering in children under 5, and in adults 30–40 years old. Adrenocortical carcinoma is remarkable for the many hormonal syndromes which can occur in patients with steroid hormone-producing tumors, including Cushing's syndrome, Conn syndrome, virilization, and feminization. Adrenocortical carcinoma has often invaded nearby tissues or metastasized to distant organs at the time of diagnosis, and the overall 5-year survival rate is only 20–35%.

  • also known as adrenal cortical carcinoma, ACC, adrenal cortex cancer

Printed dictionaries and other books with definitions for Adrenocortical carcinoma

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Google previewMultislice-CT of the Abdomen (2012)

by Christoph Johannes Zech, Carlo Bartolozzi, Richard Baron, Maximilian F. Reiser

Adrenocortical carcinoma is a rare, highly aggressive tumor ...

Google previewManagement of Adrenal Masses in Children and Adults (2016)

by Electron Kebebew

Adrenocortical carcinoma is a rare but fatal malignancy. The estimated incidence is 0.7–2.0 cases per million persons each year...

Google previewPediatric Nuclear Medicine and Molecular Imaging (2014)

by S.Ted. Treves

Adrenocortical carcinoma is a rare malignancy with a poor prognosis in childhood. Patients may present with signs of virilization due to adrenal androgen secretion. Initial imaging is by CT scans and MRI for detection of the primary, locoregional disease and lung metastases. The initial treatment is adrenalectomy and adjuvant therapy with mitotane. Recurrence rates are high and imaging is required to detect early recurFluorine-18-FDG PET/CT has been ...

Google previewSurgery (2015)

A Case Based Clinical Review by Christian de Virgilio, Paul N. Frank, Areg Grigorian

Adrenocortical carcinoma is a malignant cancer defined by the presence of local invasion into adjacent organs, blood vessels or lymph nodes, or distant metastasis.

Google previewAdvances in Nuclear Oncology: (2007)

Diagnosis and Therapy by Emilio Bombardieri, John Buscombe, Giovanni Lucignani, Otmar Schober

Adrenocortical carcinoma is an extremely rare disease. Only 60% of the carcinomas produce hormones, most of them aldosterone. Diagnosis is usually late. Metastases occur in the liver, lungs, and bones. Lymph node metastases are also common. Most adrenocortical carcinomas do not show an increased tracer uptake ...

Google previewPulmonary Cytopathology (2014)

by Yener S. Erozan, Ibrahim Ramzy

Adrenocortical carcinoma is a rare source of metastatic clear cells that should be considered. Table 9.5 summarizes the immunophenotypes of the common clear cell neoplasms. In elderly patients with a history of head and neck squamous cell carcinoma, the detection of malignancy in pulmonary specimens may still reflect the development of a new lung primary rather than metastasis, since there is an overlap ...

Google previewCarcinomas: New Insights for the Healthcare Professional: 2011 Edition (2012)

According to recent research from Tubingen, Germany, “Adrenocortical carcinoma is a rare but highly malignant neoplasm ...

Google previewPrimary Care Medicine (2016)

by CTI Reviews

Adrenocortical carcinoma is a rare tumor, with incidence of 12 per million population annually. Adrenocortical carcinoma has a bimodal distribution by age, with cases clustering in children under 5, and in adults 3040 years old. The.

Google previewGenitourinary Imaging: Case Review Series (2015)

by Satomi Kawamoto, Katarzyna J Macura

Hormonally active adrenocortical carcinomas tend to be smaller than nonfunctioning tumors at presentation. 4. C. In adults, Cushing syndrome is the most common clinical presentation for functioning adrenocortical carcinomas and is seen in approximately 30% of the hormonally active tumors. Comment. Background Adrenocortical carcinoma is a rare primary adrenal neoplasm, with an incidence of 1 to 2 per million people. They are aggressive tumors, with generally ...

Google previewGowned and Gloved Surgery (2008)

Introduction to Common Procedures by Robert E. Roses, Emily Carter Paulson, Suhail Kanchwala, Jon B. Morris

Adrenocortical Carcinoma A. Adrenocortical carcinoma is a rare tumor, affecting one to two persons per 1 million.

Google previewImaging Strategies in Oncology (1993)

by David D Stark, Daniel Vanel

Primary adrenocortical Carcinoma is an uncommon malignancy, accounting for 0.2% of all cancer deaths.” The peak incidence is in the 4th and 5th decades and both sexes are affected equally. The left gland is more commonly involved than the right; 10% of these tumors are bilateral. Adrenal carcinomas can be endocrinologically active and produce excess hormones – such tumors are termed functioning carcinomas. Excess cortisol production is the most common functional ...

Google previewMosby's Comprehensive Review for General Sonography Examinations (2016)

by Susanna Ovel

Adrenocortical carcinoma is an unlikely finding in the neonate. d. A complex mass inferior to the spleen and medial to the superior pole of the kidney is suspicious for an adrenal mass. Based on the clinical history, a solid mass of the adrenal gland in a toddler is most suspicious for a neuroblastoma. Nephroblastoma is a renal neoplasm. Adrenal hemorrhage is a possible differential but not the most likely consideration with this clinical history. Splenic rupture and intussusception are ...

Google previewThe SAGE Encyclopedia of Cancer and Society (2015)

by Graham A. Colditz

Adrenocortical carcinoma, adrenal cortex cancer, or adrenal cortical carcinoma is a cancer of the cortex of the adrenal gland. The adrenal gland is an endocrine gland near the kidneys, responsible for producing hormones in response to stress and trauma and for assisting kidney function. Humans have two adrenal glands, one proximate to each kidney: The right adrenal gland is triangular, while the left is semilunar, with each located above its respective kidney. They are small ...

Google previewConcise Dictionary of Modern Medicine (2010)

by Joseph Segen

See Acinic cell carcinoma, Adenocarcinoma, Adrenocortical carcinoma, Anaplastic carcinoma, Anaplastic carcinoma of pancreas, Anaplastic carcinoma of thyroid, Basal cell carcinoma, Basaloid carcinoma, Carcinoma in situ, CASTLE, Chromophobe cell carcinoma, Clear cell carcinoma, Collecting duct carcinoma, Colloid carcinoma, Ductal carcinoma in situ, Duct cell carcinoma, Embryonal carcinoma, Endometrial carcinoma, Epithelial carcinoma, Epithelialmyoepithelial carcinoma, ...

Google previewEncyclopedia of the Neurological Sciences (2014)

In AIMAH, the adrenals are markedly enlarged with what appear to be individual tumors or nodules, Table 2 Etiologies of Cushing's syndrome Endogenous ACTH independent Unilateral: Adrenocortical adenoma, adrenocortical carcinoma Bilateral: Micronodular adrenocortical hyperplasia, macronodular adrenocortical hyperplasia ACTH dependent Cushing's disease Ectopic ACTH syndrome Exogenous Abbreviation: ACTH, adrenocorticotropin. and the appearance of cells in ...

Google previewDorland's Dictionary of Medical Acronyms and Abbreviations (2015)

by Dorland

administrative control center; adrenocortical carcinoma; agenesis of corpus callosum; alveolar cell carcinoma; ambulatory care center; American College of Cardiology; anodal closure contraction; anterior cingulate cortex; antitoxin- containing cell; aplasia cutis congenita; articular chondrocalcinosis; automated cell count; automated cell counter Acc acceleration; adenoid cystic carcinoma acc acceleration, accelerator; accident; accommodation ACCA Advisory Committee on Casualty ...

Google previewThe Encyclopedia of Endocrine Diseases and Disorders (2005)

by William A. Petit, William A. Jr Petit, Christine A. Adamec

Adrenocortical Carcinoma: Diagnosis, Evaluation, and ...

Google previewInternational Encyclopedia of Public Health (2016)

Germline mutations of TP53 are present in most children with adrenocortical carcinoma and perhaps 10% of cases of childhood rhabdomyosarcoma and 3% ...

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