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Adrenocortical carcinoma


Adrenocortical carcinoma, also adrenal cortical carcinoma and adrenal cortex cancer, is an aggressive cancer originating in the cortex of the adrenal gland. Adrenocortical carcinoma is a rare tumor, with incidence of 1–2 per million population annually. Adrenocortical carcinoma has a bimodal distribution by age, with cases clustering in children under 5, and in adults 30–40 years old. Adrenocortical carcinoma is remarkable for the many hormonal syndromes which can occur in patients with steroid hormone-producing tumors, including Cushing's syndrome, Conn syndrome, virilization, and feminization. Adrenocortical carcinoma has often invaded nearby tissues or metastasized to distant organs at the time of diagnosis, and the overall 5-year survival rate is only 20–35%.

  • also known as adrenal cortical carcinoma, ACC, adrenal cortex cancer

Printed dictionaries and other books with definitions for Adrenocortical carcinoma

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Google previewMultislice-CT of the Abdomen (2012)

by Christoph Johannes Zech, Carlo Bartolozzi, Richard Baron, Maximilian F. Reiser

Adrenocortical carcinoma is a rare, highly aggressive tumor with prevalence of 0.6–2 per million population (Mansmann et al. 2004). Approximately 50% of the carcinomas are hormonally active, most commonly ...

Google previewCytopathology of Liver, Biliary Tract, Kidney and Adrenal Gland (2014)

by Yener S. Erozan, Armanda Tatsas

Adrenocortical carcinoma is an extremely rare tumor, mostly found in persons between 40 and 50 years of age. The tumor is usually very...

Google previewCushing's Disease (2011)

by Brooke Swearingen, Beverly M. K. Biller

Adrenocortical carcinoma is a rare malignancy with only two new cases per million population per year. It occurs with a bimodal age distribution peaking before age 5 and from ages 50–60 [87]. Adrenocortical ...

Google previewPrinciples and Management of Adrenal Cancer (2012)

by Nasser Javadpour

Adrenal Carcinoma Adrenocortical carcinoma is a rare cancer arising in the adrenal cortex and it frequently retains the ability to synthesize steroids. Adrenocortical cancer is a slow-growing tumor with a relatively low propensity for metastasis ...

Google previewCarcinoma of the Kidney and Testis, and Rare Urologic Malignancies (2013)

Innovations in Management by Zbigniew Petrovich, Luc Baert, Luther W. Brady

Adrenocortical Carcinoma Primary adrenocortical carcinoma is a rare tumor that generally carries a poor ...

Google previewPediatric Nuclear Medicine and Molecular Imaging (2014)

by S.T. Treves

Adrenocortical Carcinoma Adrenocortical carcinoma is a rare malignancy with a poor prognosis in childhood.

Google previewSurgery (2015)

A Case Based Clinical Review by Christian de Virgilio, Paul N. Frank, Areg Grigorian

Adrenocortical carcinoma is a malignant cancer defined by the presence of local invasion into adjacent organs, blood vessels or lymph nodes, or distant metastasis.

Google previewGenitourinary Imaging: Case Review Series (2015)

by Satomi Kawamoto, Katarzyna J Macura

Background Adrenocortical carcinoma is a rare primary adrenal neoplasm, with an incidence of 1 to 2 per million people. They are aggressive tumors, with generally poor prognosis.

Google previewTextbook of Clinical Trials (2016)

Medicine, Medical research by CTI Reviews

Adrenocortical carcinoma is a rare tumor, with incidence of 1 2 per million population annually. Adrenocortical carcinoma hasa bimodal distribution by age, withcasesclustering inchildren under 6, andin adults 3040 yearsold. congenital ...

Google previewAdvances in Nuclear Oncology: (2007)

Diagnosis and Therapy by Emilio Bombardieri, John Buscombe, Giovanni Lucignani, Otmar Schober

Adrenocortical carcinoma is an extremely rare disease. Only 60% of the carcinomas produce hormones, most of them aldosterone. Diagnosis is usually late. Metastases occur in the liver, lungs, and bones. Lymph node metastases are also ...

Google previewPulmonary Cytopathology (2014)

by Yener S. Erozan, Ibrahim Ramzy

Adrenocortical carcinoma is a rare source of metastatic clear cells that should be considered. Table 9.5 summarizes the immunophenotypes of the common clear cell neoplasms. In elderly patients with a history of head and neck squamous ...

Google previewPrimary Care Medicine (2016)

by CTI Reviews

Adrenocortical carcinoma is a rare tumor, with incidence of 12 per million population annually. Adrenocortical carcinoma has a bimodal distribution by age, with cases clustering in children under 5, and in adults 3040 years old. The.

Google previewMosby's Comprehensive Review for General Sonography Examinations (2016)

by Susanna Ovel

Adrenocortical carcinoma is an unlikely finding in the neonate. d. A complex mass inferior to the spleen and medial to the superior pole of the kidney is suspicious for an adrenal mass. Based on the clinical history, a solid mass of the adrenal ...

Google previewGowned and Gloved Surgery (2008)

Introduction to Common Procedures by Robert E. Roses, Emily Carter Paulson, Suhail Kanchwala, Jon B. Morris

Adrenocortical Carcinoma A. Adrenocortical carcinoma is a rare tumor, affecting one to two persons per 1 million. The median age at diagnosis is 44 years. Between 60% and 80% of these tumors are functional. Nonfunctional tumors often ...

Google previewNelson Textbook of Pediatrics (2016)

by CTI Reviews

Adrenocortical carcinoma is a rare tumor, with incidence of 1 2 per million population annually. Adrenocortical carcinoma hasa bimodal distribution by age, withcases clustering in children under 6,and in adults 3040years old. CHAPTER QUIZ: ...

Google previewAdrenal Imaging (2009)

by Michael A. Blake, Giles Boland

Adrenocortical carcinoma is an aggressive malignancy, which frequently violates the tumor capsule and invades surrounding tissues. It metastasizes to lungs, liver , brain and regional lymph nodes. Many patients present with widespread ...

Google previewClinical Endocrine Oncology (2009)

by Ian D. Hay, John A. H. Wass

Virilizing adrenal tumors are relatively rare and are usually adrenocortical carcinomas. Adrenocortical carcinoma is a rare malignancy (0.02 % ofall cancers) with an incidence of1 per million and is more common in women than men [9].

Google previewImaging Strategies in Oncology (1993)

by David D Stark, Daniel Vanel

Primary adrenocortical Carcinoma is an uncommon malignancy, accounting for 0.2% of all cancer deaths.” The peak incidence is in the 4th and 5th decades and both sexes are affected equally. The left gland is more commonly involved than ...

Google previewElective General Surgery (2012)

An Evidence-Based Approach by Cohn, Stephen M. Cohn, Steven T. Brower

Adrenocortical carcinoma is a rare tumor that most commonly presents with advanced disease precluding complete resection. For patients with localized disease, surgical resection offers the only chance of cure, with median survival of 101 ...

Google previewThe SAGE Encyclopedia of Cancer and Society (2015)

by Graham A. Colditz

Adrenocortical carcinoma, adrenal cortex cancer, or adrenal cortical carcinoma is a cancer of the cortex of the adrenal gland. The adrenal gland is an endocrine gland near the kidneys, responsible for producing hormones in response to stress ...

Google previewEncyclopedia of Cancer (2011)

by Manfred Schwab

Childhood Adrenocortical Carcinoma. Table 1 Constitutional syndromes associated with adrenocortical tumors Childhood Cancer. Fig. 2 (a, b) Childhood cancer SEER incidence. Condition 7 H V Germline TP53 mutations, ...

Google previewThe Encyclopedia of Endocrine Diseases and Disorders (2005)

by William A. Petit, William A. Jr Petit, Christine A. Adamec

Adrenocortical Carcinoma: Diagnosis, Evaluation, and Treatment.” Journal of ...

Google previewDorland's Dictionary of Medical Acronyms and Abbreviations (2015)

by Dorland

acetyl–coenzyme A carboxylase; acinic cell carcinoma; actinomycin C; acute care center; adenoid cystic carcinoma; administrative control center; adrenocortical carcinoma; agenesis of corpus callosum; alveolar cell carcinoma; ambulatory ...

Google previewEncyclopedia of the Neurological Sciences (2014)

In AIMAH, the adrenals are markedly enlarged with what appear to be individual tumors or nodules, Table 2 Etiologies of Cushing's syndrome Endogenous ACTH independent Unilateral: Adrenocortical adenoma, adrenocortical carcinoma ...

Google previewA Dictionary of Genetic Damage (2003)

by Nils Oeijord

genetic damage of Adrenal medulla neoplasm, genetic damage of Adrenocortical carcinoma, genetic damage of Adrenogenital syndrome, genetic damage of Adrenoleukodystrophy, genetic damage of Adrenoleukodystrophy, autosomal, ...

Google previewThe Dictionary of Modern Medicine (1992)

by J.C. Segen

an adenoma or rarely, an adrenocortical carcinoma of the adrenal cortex, especially the Zona glomerulosa Pseudohyperhypoparathyroidism see Pseudohypohyperparathyroidism Pseudohyperkalemia LABORATORY MEDICINE An in vitro ...

Google previewDorland's Illustrated Medical Dictionary (2011)

by Dorland

adrenocorticosteroid production; used for palliation in inoperable adrenocortical carcinoma of both functional and nonfunctional types, administered orally. mi•to•xan•trone hy•dro•chlo•ride (mi00to-zan0tro ̄n) [USP] a DNAintercalating agent ...

Google previewEncyclopedia of Molecular Mechanisms of Disease (2009)

With 213 Tables by Florian Lang

Sporadic aldosterone-producing adrenal adenoma, aldosterone-producing adrenocortical carcinoma, unilateral adrenal cortex ...

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