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Header of Adriamycin


Definition of the noun Adriamycin

What does Adriamycin mean as a name of something?

noun - plural: Adriamycins

  1. An anthracycline antibiotic drug used in cancer chemotherapy.


Adriamycin RDF is a drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. Adriamycin RDF comes from the bacterium Streptomyces peucetius. It damages DNA and stops cells from growing. Rapidly growing tumor cells that take up Adriamycin RDF may die. It is a type of anthracycline antitumor antibiotic. Also called doxorubicin hydrochloride, doxorubicin, Adriamycin PFS, and Rubex.

  • also known as Doxorubicin, Adriamycin PFS, Rubex, Doxorubicin hydrochloride, Adriamycin RDF


Adriamycin a.k.a. Doxorubicin: An anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects.

Printed dictionaries and other books with definitions for Adriamycin

Click on a title to look inside that book (if available):

Google previewReport on Carcinogens (12th Ed. ) (2011)

by Nat. Toxicology Program (NTP) (NIH)

Adriamycin is an anthracycline antibiotic that is an almost odorless red crystalline solid. It is soluble in water and...

Adriamycin is a prescription drug subjectto labeling and other requirements .

Google previewEncyclopedia of Cancer (2008)

by Manfred Schwab

Pharmaceutical Sciences, Tohoku University, Sendai, Japan Synonyms Doxorubicin; l4-Hydroxyldaunorubicin Definition Adriamycin is an antineoplastic >anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius.

Google previewNCLEX-RN in a Flash (2009)

by Ray A. Gapuz

POINTERS • Adriamycin is an antineoplastic antibiotic. • Best taken in the morning • May turn the...

Adriamycin is a cytotoxic drug, therefore the nurse should instruct the client to increase oral fluid intake during the course of therapy.

Google previewSittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens (2017)

by Richard P. Pohanish

Description: Adriamycin is an orange to red cake-like or needle-like crystalline solid. Molecular weight5543.6; freezing/melting...

There is limited evidence that adriamycin is a teratogen in animals. Causes baldness, stomatitis, and bone ...

Google previewOvarian Cancer (2012)

by David Alberts, Earl A. Surwit

Adriamycin is an antibiotic obtained from a streptomyces species and is a hydroxylated congener of daunorubicin. It appears to exert its effect by intercalation between adjoining nucleotide pairs in DNA [45] and hence to prevent ...

Google previewAnimal models in cardiovascular research (2013)

by D.R. Gross

(Adriamycin is an anthracycline antibiotic widely used for chemotherapy) Same as above Cardiac myocytes Intrinsic changes in 186 enzymatically isolated showed a decrease in contraction amplitude, velocity and oxygen consumption ...

Google previewCancer in Childhood (2012)

by John O. Godden

We used vincristine, actinomycin-D and cyclophosphamide in combination initially, but Adriamycin is an effective agent, which will produce significant regression of disease in a high proportion of patients. Its major limitation is cardiotoxicity, ...

Google previewHematologic Malignancies (2012)

by Barth Hoogstraten

Hydroxydaunorubicin (Adriamycin) Adriamycin is an antibiotic which is administered intravenously as part of a drug combination.

Google previewBathsheba's Breast (2005)

Women, Cancer, and History by James S. Olson

Adriamycin is an antibiotic cancer drug with extremely powerful properties. Antibiotics fight infectious diseases, but adriamycin is too toxic for such uses. In cancer patients, the drug kills malignant cells by inserting itself into strands of DNA and ...

Google previewMale Fertility and Its Regulation (2012)

by E.S. Hafez, Thomas Lobl

Adriamycin is a potent anti- cancer antibiotic which is effective against a wide variety of neoplastic diseases ( Carter, 1975).

Google previewThe Target Organ and the Toxic Process (2012)

Proceedings of the European Society of Toxicology Meeting Held in Strasbourg, September 17–19, 1987 by Philip L. Chambers, Claire M. Chambers, Guy Dirheimer

Adriamycin is an anthracycline antibiotic widely used as an antitumoral ...

Google previewJohns Hopkins Patients' Guide to Lymphoma (2010)

by Aditya Bardia, Eric J. Seifter

Adriamycin is a chemotherapy agent that can cause future heart problems. To help evaluate if it is safe and appropriate to give these medications, a special heart scan using a MUGA (multiplegated acquisition) scan or an echocardiogram is ...

Google previewContemporary Nephrology (2012)

by Saulo Klahr, Carolyn Mercer

Adriamycin is an anthracycline antineoplastic drug which causes glomerular and tubular lesions in animals and occasionally in humans. Tubulointerstitial inflammatory changes, rather than consequences of drug-induced proteinuria, seem to ...

Google previewErgebnisse der Adriamycin-Therapie (2013)

Adriamycin-Symposium Frankfurt/Main 1974 by M. Ghione, J. Fetzer, H. Maier

Johnson Laboratory of Experimental Chemotherapy, Drug Research and Development, Division of Cancer Treatment, National Cancer Institute, Bethesda, MD 20014, USA Adriamycin is an active drug of pronounced clinical interest.

Google previewInternational Symposium on Adriamycin (2012)

Milan, 9th-10th September, 1971 by Stephen K. Carter, A. Di Marco, M. Ghione, I.H. Krakoff, G. Mathe

Adriamycin is a tetracyclic anthracycline antibiotic with substantial antitumor activity in transplanted rodent tumors. It is a 14hydroxy derivative and thus a close analog of daunorubicin. Its spectrum of antitumor activity in experimental systems is ...

Google preview6th Annual Report on Carcinogens (1991) (1994)

by DIANE Publishing Company

PROPERTIES Adriamycin is a red, crystalline solid with a melting point of 204° C. It is soluble in water and aqueous alcohols, moderately soluble in anhydrous methanol, and insoluble in nonpolar organic solvents. Neutral aqueous solutions ...

Google previewCancer Registry Management (2004)

Principles & Practice by National Cancer Registrars Association

Adriamycin is an anticancer drug which has a side-effect of cardiac t. TQM total quality management; the process of quality; quality from start to finish. A corporationwide belief that everyone in the organization is responsible for assuring that ...

Google previewVitamins (1988)

by Wilhelm Friedrich

Adriamycin is a quinoid antibiotic of the anthra- cycline series; it is widely used in the treatment of neoplastic diseases. Its clinical application has limits, however, mainly due to the damage it causes in heart muscle. Some studies indicate that ...

Google previewDictionary of Medical Abbreviations (2016)

The World's most comprehensive list of English-language medical abbreviations and acronyms by Burt Vance

ABu= aminobutyric acid ABU = asymptomatic bacteriuria ABUS= automated breast ultrasound system ABV = actinomycin D, bleomycin, vincristine ABV= adriamycin, bleomycin, vinblastine ABV = African bee venom ABV = agaricus bisporus ...

Google previewInverted Medical Dictionary, Second Edition (1991)

by Bruce C. Carlstedt, Mary J. Stanaszek, Walter F. Stanaszek

ECHO etoposide, cyclophosphamide, Adriamycin®, vincristine EDTA ethylene- dinitrilo tetraacetic acid (edetic acid) EES® erythromycin ethylsuccinate EHDA etidronate sodium EMB ethambutol EOG Ethrane®, oxygen and gas EPA ...

Google previewConcise Dictionary of Biomedicine and Molecular Biology (2001)

by Pei-Show Juo

MABOP Abbreviation for a combination drug containing mechlorethamine, adriamycin, bleomycin, oncovin, and prednisone. Mabuterol (mol wt 311) A bronchodilator and an antiasthmatic agent. F3C OH H2N CHCH2NHC(CH3)3 Cl MAC ...

Google previewThe Encyclopedia of Women's Reproductive Cancer (2005)

by Carol Turkington, Mitchell Edelson

Adriamycin (doxorubicin) A type of intravenous (IV) ...

Google previewEncyclopedia of Physical Organic Chemistry, , 6 Volume Set (2017)

by Zerong Wang

Adriamycin Adriamycin pH-triggered drug release ...

Google previewDictionary of Abbreviations in Medical Sciences (2012)

With a list of the most important medical and scientific journals and their traditional abbreviations by Rolf Heister

French Association of Maxillofacial Surgeons AFCM regimen cytotoxic combination therapy with: adriamycin, 5fluorouracil, cyclophosphamide, and methotrexate AFCP AFCR antibody forming cell precursors American Federation for Clinical ...

Google previewJablonski's Dictionary of Medical Acronyms & Abbreviations (2008)

by Stanley Jablonski

adrenalin; adrenals; adrenergic receptor; adrenodoxin reductase; Adriamycin; adverse drug reaction; airway dilation reflex; alternative dispute resolution; arrested development of rightingresponse ...

Google previewDorland's Dictionary of Medical Acronyms and Abbreviations (2015)

by Dorland

ADLS Activities of Daily Living Survey ADM abductor digitiminimi; add-drop multiplexer; administrative medicine; admission; Adriamycin; advanced diabetes management AdM adrenal medulla adm administration; admission; ...

Google previewTaber's Cyclopedic Medical Dictionary (2017)

by Donald Venes

CAF (cyclophosphamide, doxorubicin [ Adriamycin], and fluorouracil), AC (doxorubicin [Adriamycin] and cyclophosphamide), ...

Google previewThe Dictionary of Cell & Molecular Biology (2007)

by John M. Lackie

adriamycin. contact area. On the cytoplasmic face are local concentrations of various proteins such as vinculin and talin. adhesion site 1. In Gram-negative bacteria, a region where the outer membrane and the plasmalemma appear to fuse.

Google previewDictionary of Carbohydrates (2005)

by Peter M. Collins

A-58 Adriamycin, 8CI Doxorubicin, BAN, INN, USAN. 14-Hydroxydaunomycin. Adriacin. Adriblastin. Caelyx. Dox. Doxil. Farmiblastina.

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Video about Adriamycin

Adriamycin Meaning

Video shows what adriamycin means. An anthracycline antibiotic drug used in cancer chemotherapy.. adriamycin synonyms: doxorubicin, hydroxydaunorubicin.

See also the pronunciation examples of Adriamycin!

Scrabble value of A1D2R1I1A1M3Y4C3I1N1

The value of this 10-letter word is 18 points. It is included in the first and second editions of the Official Scrabble Players Dictionary.

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