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Albuterol Sulfate: The sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of-albuterol and-albuterol with bronchodilator activity. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate. Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.
Printed encyclopedias and other books with definitions for Albuterol Sulfate
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Bioequivalence Issues by Isadore Kanfer, Leon Shargel
Albuterol sulfate is a synthetic sympathomimetic amine and a selective b2adrenergic bronchodilator. Albuterol is administered either by inhalation or Table 7 FEV1 and PD20 FEV1 Values Measured in the ...
FDA Bioequivalence Standards (2014)
by Lawrence X. Yu, Bing V. Li
Albuterol sulfate is a beta2-adrenergic agonist. Albuterol relaxes the smooth muscle of airways, thus protecting against all bronchoconstrictor challenges. Due to the limited relevance of PK data to drug delivery to the target sites, PK data alone ...
by William Llewellyn
Albuterol sulfate is a CNS stimulant with potential for fatal overdose. Signs of overdose may include rapid breathing, blood pressure irregularities, irregular heartbeat, unconsciousness, trembling, shaking, panic, extreme restlessness, and ...
by Manuchair Ebadi
IPRATROPIUM BROMIDE/ALBUTEROL SULFATE (Combivent aerosol 18 mcg ipratropium bromide and 103 mcg albuterol sulfate per actuation) Ipratropium bromide/albuterol sulfate is an anticholinergic preparation. Albuterol produces ...
Encyclopedia of Toxicology (2005)
by Bruce Anderson, Ann de Peyster, Shayne C. Gad, P.J. Bert Hakkinen, Michael Kamrin, Betty Locey, Harihara M. Mehendale, Carey Pope, Lee Shugart
Cary, NC, USA • CHEMICALA BSTRACTS S ERVICE R EGISTRY N UMBER : CAS 18559949 • S YNONYMS : Salbutamol; Ventolin; Proventil; Apo Salvent; NovoSalmol; Albuterol sulfate; ...
by Carol Turkington, Mitchell Edelson
If the tumor narrows or blocks the bronchial tubes, a bron- chodilator such as albuterol sulfate (Ventolin) can be administered through an inhaler or a nebulizer .
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