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Aldolase

Definition of the noun Aldolase

What does Aldolase mean as a name of something?

noun - plural: aldolases

  1. [enzyme] An enzyme, present in some tissue, that catalyses the conversion of phosphates of fructose to those of glyceraldehyde and dihydroxyacetone

Explanation

  1. Aldolase: An aldolase is an enzyme that performs an aldol reaction or its reverse. The word often refers to any type of fructose-bisphosphate aldolase, but can also refer to other enzymes, such as the one that forms sialic acid.
  2. Aldolase a.k.a. Aldolase A is an enzyme that catalyses a reversible aldol reaction: The substrate, fructose 1,6-bisphosphate is broken down into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. This reaction is a part of glycolysis. Three fructose-bisphosphate aldolase isozymes, encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney, and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants that encode the same protein.

Printed dictionaries and other books with definitions for Aldolase

Click on a title to look inside that book (if available):

Google previewPediatric Oncology 1 (2012)

with a special section on Rare Primitive Neuroectodermal Tumors by G. Bennett Humphrey, Louis P. Dehner, Gerald B. Grindey, Ronald T. Acton

Aldolase is an enzyme in the glycolytic sequence, and the rationale for investigating aldolase activity measurments in physiological fluids is the same as for LDH. In addition, several early reports[56–59] indicated that differences in the ...

Google previewDelmars Guide to Laboratory and Diagnostic Tests (2016)

Medicine, Medicine by CTI Reviews

An aldolase is an enzyme that performs an ...

Google previewBiochemistry, 6th Edition (2016)

by CTI Reviews

Aldolase: An aldolase is an enzyme that cleaves an aldol.

Google previewMicrobial Biotechnology, Fundamentals of Applied Microbiology (2016)

by CTI Reviews

Aldolase: An aldolase is an enzyme, such as fructosebisphosphate aldolase,

Google previewPhlebotomy: From Student to Professional (2010)

by Bonnie Karen Davis

Aldolase is a glycolytic enzyme that catalyzes the breakdown of ...

Google previewBiochemistry and Molecular Biology of Plants (2016)

Biology, Biochemistry by CTI Reviews

An aldolase is an enzyme that performs an aldol reaction or its reverse (cleaving an aldol). The word often refers to ...

Google previewMedical Biochemistry (2014)

by John Baynes, Marek H. Dominiczak

The liver aldolase is called aldolase B, and it is different in substrate specificity ...

Google previewThe Cleveland Clinic Intensive Review of Internal Medicine (2012)

by James K. Stoller, Franklin A. Michota, Brian F. Mandell

Aldolase is an enzyme found in the glycolytic pathway, downstream of phosphofructokinase. It is found in muscle fast-twitch fibers, as well as in liver, kidney, brain, intestines, and fetal tissue. AST and ALT can be elevated into the several ...

Google previewMosby's Diagnostic and Laboratory Test Reference (2014)

by Kathleen Deska Pagana, Timothy J. Pagana, Theresa N Pagana

Aldolase is an enzyme used in glycolysis (breakdown of glucose). As with AST and creatine phosphokinase, aldolase exists throughout the body in most tissues. This test is most useful for indicating muscular or hepatic cellular injury or ...

Google previewGeneral, Organic, and Biochemistry (2016)

Chemistry, Chemistry by CTI Reviews

Aldolase: An aldolase is an enzyme that performs an aldol reaction or its reverse (cleaving an aldol). The word often refers to any type of fructosebisphosphate aldolase, but can also refer tootherenzymes, such as the one that forms sialic acid.

Google previewFrom Molecules to Networks (2014)

An Introduction to Cellular and Molecular Neuroscience by John H. Byrne, Ruth Heidelberger, M. Neal Waxham

Aldolase is a glycolytic enzyme (Fig. 3.4) that converts fructose 1,6- bisphosphate to glyceraldehyde 3-phosphate and dihy- droxyacetone phosphate, and it also has noncatalytic roles as a scaffold protein that can bind to F-actin, α-tubulin, ...

Google previewEncyclopedia of Parasitology: A-M (2008)

by Heinz Mehlhorn, Horst Aspöck

Microneme proteins become inserted in the plasmalemma and associate with short actin filaments through an aldolase. The actin-aldolase- microneme protein complexes are translocated by the myosin motor while interacting with the ...

Google previewEncyclopedia of Human Nutrition, Four-Volume Set (2005)

by Lindsay Allen, Andrew Prentice

The aldolase A, B, and C enzymes catalyze the reversible conversion of fructose- 1-diphosphate into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate, and deficiencies in the A and B enzymes have been identified. Aldolase A is ...

Google previewEncyclopedia of Microbiology (2009)

KDPG is then split by the enzyme KDPG aldolase into pyruvate and GAP. GAP can then be converted to pyruvate through the triose phosphate portion of the EMP pathway producing two ATP and one NADH/Hþ. Thus, a single glucose ...

Google previewDesk Encyclopedia of Microbiology (2010)

by Moselio Schaechter

The KDPG is then split by KDPG aldolase to pyruvate and GAP. GAP can then be further metabolized to pyruvate using the enzymes of the triose phosphate portion of the EMP pathway. The phosphorylation of the six-carbon KDG allows for the ...

Google previewEncyclopedia of Genetics, Genomics, Proteomics, and Informatics (2008)

by George P. Rédei

There is also a deoxyribose-5-phosphate aldolase but its deficiency is apparently harmless. ALDOA deficiency may be involved in a form of hemolytic anemia (γ- glutamylcysteine synthetase deficiency). ▷fructose intolerance, ▷anemia ...

Google previewMosby's Dictionary of Medicine, Nursing and Health Professions - Australian & New Zealand Edition (2014)

by Peter Harris, Sue Nagy, Nicholas Vardaxis

aldolase/alމdۑlƗs/, enzyme found in muscle tissue that catalyses the step in anaerobic glycolysis involving the breakdown of fructose 1,6- biphosphate to glyceraldehyde 3-phosphate (GAP). The enzyme can also catalyse the ...

Google previewThe Lupus Encyclopedia (2014)

A Comprehensive Guide for Patients and Families by Donald E. Thomas, Jr.

Aldolase. Aldolase is an enzyme that appears in all cells ofthe body. However, the highest amounts are in muscles, the brain, and the liver. The test is mainly used in people who have SLE to determine if they have inflammation of the muscles ...

Google previewThe Encyclopedia of Genetic Disorders and Birth Defects (2009)

by James Wynbrandt, Mark D. Ludman

fructose intolerance (fructose-1-phosphate aldolase deficiency) Fructose is a sugar present in foods such as fruits, sugar cane, corn syrup, honey and fruit juices. Table sugar or sucrose contains fructose and glucose. Fructose intolerance ...

Google previewEncyclopedia of Food and Health (2015)

The aldolase A, B, and C enzymes (EC 4.1.2.13) catalyze the reversible conversion of fructose-1-diphosphate into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate, and deficiencies in the A and B enzymes have been identified.

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Video about Aldolase

Aldolase Meaning

Video shows what aldolase means. An enzyme, present in some tissue, that catalyses the conversion of phosphates of fructose to those of glyceraldehyde and ...

Scrabble value of A1L1D2O1L1A1S1E1

The value of this 8-letter word is 9 points. It is included in the first and second editions of the Official Scrabble Players Dictionary.

Anagrams of ALDOLASE

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