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Allopurinol

Definition of the noun Allopurinol

What does Allopurinol mean as a name of something?

noun - plural: allopurinols

  1. A drug used primarily to treat hyperuricemia and its complications.

Explanation

Allopurinol: A structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to uric acid. By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, thereby providing protection against uric acid-mediated end organ damage in conditions associated with excessive production of uric acid, i.e. the massive cell lysis associated with the treatment of some malignancies.

  • also known as 알로퓨리놀, แอลโลพูรินอล, 别嘌醇

Printed dictionaries and other books with definitions for Allopurinol

Click on a title to look inside that book (if available):

Google previewe-Study Guide for: Medical-Surgical Nursing, Volume 1 and Volume 2 by Donna D. Ignatavicius, ISBN 9780721606712 (2012)

by Cram101 Textbook Reviews

Allopurinol: Allopurinol is a drug used primarily to treat hyperuricemia (excess uric acid in blood plasma) and its complications, including chronicgout. Mechanismofaction Allopurinol is a purine analog; it is a structural isomer of hypoxanthine ...

Google previewe-Study Guide for: Essential Surgery: Problems, Diagnosis and Management (2012)

Medicine, Surgery by Cram101 Textbook Reviews

Allopurinol: Allopurinol is a drug used primarily to treat hyperuricemia (excess uric acid in blood plasma) and its complications, including chronic gout. Mechanismofaction Allopurinol is a structural isomer of hypoxanthine (a naturally occurring ...

Google previewe-Study Guide for: Merritts Neurology (2012)

by Cram101 Textbook Reviews

Allopurinol is a drug used primarily to treat hyperuricemia (excess uric acid in blood plasma) and its complications, including chronic gout. Allopurinol is a structural isomer of hypoxanthine (a naturally occurring purine in the body) and is an ...

Google previewThe Molecular Basis of Cancer (2012)

by Peter B. Farmer, John M. Walker

Allopurinol is a drug that inhibits xanthine oxidase, an enzyme that converts hypoxanthine into xanthine and xanthine into uric acid. Uric acid is sparingly soluble in urine and can precipitate in the distal renal tubules causing damage to the ...

Google previewBrigham Intensive Review of Internal Medicine (2014)

by Ajay K. Singh, Joseph Loscalzo

Allopurinol is the standard treatment for both the prevention and treatment of hyperuricemia. Allopurinol is an inhibitor of xanthine oxidase and is extremely well tolerated. The most common adverse reaction is an erythematous skin rash due to ...

Google previewInternal Medicine (2012)

An Intensive Review by Ajay K. Singh, Joseph Loscalzo

Allopurinol is the standard treatment for both the prevention and treatment of hyperuricemia. Allopurinol is an inhibitor of xanthine oxidase and is extremely well tolerated. The most common adverse reaction is an erythematous skin rash due to ...

Google previewPhacoemulsification, Fourth Edition (2011)

by Amar Agarwal, Athiya Agarwal, Soosan Jacob

Allopurinol is an antihyperuricemic drug widely used for the treatment of hyperuricemia and chronic gout. It inhibits the terminal step in uric acid synthesis, which results in a reduction of uric acid concentrations in both serum and ...

Google previewHandbook of ICU Therapy (2014)

by John Fuller, Jeff Granton, Ian McConachie

Allopurinol is a hypoxanthine analog that competitively inhibits xanthine oxidase and blocks the conversion of the metabolism of ...

Google previewSmall Animal Therapeutics (2013)

by R. J. Martin

Allopurinol acts to reduce the plasma uric acid concentration and the urinary output of the urates by inhibiting an enzyme ( xanthine oxidase). Allopurinol is a competitive antagonist of xanthine oxidase and leads ...

Google previewThe Top 100 Drugs (2014)

Clinical Pharmacology and Practical Prescribing by Andrew Hitchings, Dagan Lonsdale, Daniel Burrage, Emma Baker

Allopurinol is a xanthine oxidase inhibitor. Xanthine oxidase metabolises xanthine (produced from purines) to uric acid. Inhibition of xanthine oxidase lowers plasma uric acid concentrations and reduces precipitation of uric acid in the joints or ...

Google previewClinical Light Damage to the Eye (2012)

by David Miller

Allopurinol is a commonly used antihyperuricemic agent in treating gout. Scattered reports have appeared regarding the possible relationship between the development of lens opacities in relatively young patients (second to fourth decade) ...

Google previewUSMLE Step 1 QBook

Allopurinol inhibits the formation of uric acid by blocking the conversion of hypoxanthine to xanthine and xanthine to uric acid by xanthine oxidase ( allopurinol is an analog of hypoxanthine). If uric acid synthesis is decreased, you would expect ...

Google previewFanaroff and Martin's Neonatal-Perinatal Medicine (2010)

Diseases of the Fetus and Infant by Richard J. Martin, Avroy A. Fanaroff, Michele C. Walsh

Allopurinol is an inhibitor of xanthine oxidase and has free radical scavenging action, but in a study involving 32 TABLE 40–8 ...

Google previewPediatric Urology (2009)

by John G. Gearhart, Richard C. Rink, Pierre D. E. Mouriquand

Allopurinol dosage must not exceed 4 mg/kg to avoid xanthine accumulation and xanthine stones. Other Purine Stones. In homozygous APRT deficiency, allopurinol is an effective drug to reduce DHA production.

Google previewEncyclopedia of Parasitology: A-M (2008)

by Heinz Mehlhorn, Horst Aspöck

analogue, allopurinol (see Table 1, also -»Trypanocidal Drugs, Man/Drug Acting on American Trypanosomiasis (Chagas7 Disease) of Humans) or parenteral and topical formulations of the ...

Google previewEncyclopedia of Genetics, Genomics, Proteomics, and Informatics (2008)

by George P. Rédei

Allopurinol (hydroxypyrazole pyrimidine): Allopurinol is an inhibitor of de novo pyrimidine synthesis and xanthine oxidase activity (see Fig. A54). It is used as a medicine to treat gout and hyperuricemia, but can also cause severe skin disease ...

Google previewBlack's Veterinary Dictionary (2001)

by Edward Boden

Allopurinol. (1) The treatment of choice for LEISHMANIASIS in dogs. Given by mouth, it is well absorbed from the gastrointestinal tract and excreted by the kidneys. (2) It is also used in dogs to treat UROLITHIASIS.

Google previewEncyclopedia of Cancer (2011)

by Manfred Schwab

Allopurinol. Definition A xanthine oxidase inhibitor, which is used to inhibit uric acid formation; utilized in the chronic treatment of gout to retard the rapid metabolic degradation of 6-mercaptopurine and to prevent tumor lysis syndrome.

Google previewConcise Colour Medical Dictionary (2015)

by Elizabeth Martin

allopurinol. n. a drug used for the prevention of acute attacks of *gout and ...

Google previewThe Encyclopedia of Natural Medicine Third Edition (2012)

by Michael T. Murray, JOSEPH PIZZORNO

The drug allopurinol, a structural isomer of hypoxanthine (a naturally occurring purine in the body), has been the mainstay treatment for decades. However, in February 2009 the FDA approved febuxostat (Uloric), another xanthine oxidase ...

Google previewMosby's Dictionary of Medicine, Nursing and Health Professions - Australian & New Zealand Edition (2014)

by Peter Harris, Sue Nagy, Nicholas Vardaxis

Allopurinol, a xanthine-oxidase inhibitor, is administered orally to inhibit uric acid production. Allopurinol is administered only during the initial diagnosis phase, when tumour lysis syndrome is of concern. Induction phase lasts 4 weeks.

Google previewConcise Dictionary of Pharmacological Agents (2012)

Properties and Synonyms by I.K. Morton, Judith M. Hall

Zyloprim" - allopurinol. Zyloric" - allopurinol. Zyprexa" = olanzapine. Appendix A Glossary SMALL CAPs = drug families (by mechanism or application) bold = individual agents italic = Latin or Greek, optical isomers; emphasis.

Google previewEncyclopaedic Dictionary of Biology (2003)

by S. Choudhary

alloimmune allopurinol dissimilar donor (of the same species) and stages an immune attack against it. alloimmune : Indicates or refers to an organism's being immune to proteins, cells, or other antigens from members of its own species.

Online dictionaries and encyclopedias with entries for Allopurinol

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Video about Allopurinol

Allopurinol Meaning

Video shows what allopurinol means. A drug used primarily to treat hyperuricemia and its complications.. Allopurinol Meaning. How to pronounce, definition ...

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Scrabble value of A1L1L1O1P3U1R1I1N1O1L1

The value of this 11-letter word is 13 points. It is included in the first and second editions of the Official Scrabble Players Dictionary.

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