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Definition of the adjective Allosteric

What does Allosteric mean as an attribute of a noun?


  1. [context: biochemistry, of an enzyme] That binds a compound on an inactive site and thus changes conformation in order to become either active or inactive

Printed dictionaries and other books with definitions for Allosteric

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Google previewIntroduction to Molecular Biology, Genomics and Proteomics for Biomedical Engineers (2008)

by Robert B. Northrop, Anne N. Connor

Nature has developed several means of regulating the activity of functional enzymes: One means is called allosteric regulation. Some enzymes...

Google previewCognitive Biology (2011)

Dealing with Information from Bacteria to Minds by Gennaro Auletta

Allosteric is a protein that can be in two ...

Google previewCirculation, Respiration, and Metabolism (2012)

Current Comparative Approaches by Raymond Gilles

Allosteric effects upon enzyme activity (1) immediately comes to mind as a way in which pH can regulate cell function. Such an effect would be in essence a structural (allosteric means change in shape) changes. However, there are four other ...

Google previewConcise Dictionary Of Chemistry (2012)

by V&S Publishers' Editorial Board

and having general formula CnH2n-2 Allosteric binding sites Allosteric binding sites are contained in many enzymes and receptors.

Google previewA Dictionary of Chemistry (2008)

by John Daintith

allosteric. enzyme. An enzyme thathas two structurallydistinct forms,one ofwhich is activeand the otherinactive.In theactiveform, thequaternary structure (see PROTEIN) of the enzyme issuch that asubstrate can interact with the enzyme at the ...

Google previewEncyclopaedic Dictionary of Biotechnology (2005)

Allosteric protein : A protein whose shape is changed when it binds a particular molecule. In the new shape the protein's ability to react to a second molecule is altered. Allosteric regulation : Allosteric regulation is the regulation of the activity of ...

Google previewEncyclopedia of Biology (2016)

by CTI Reviews

Effectors that enhance the protein's activity are referred to as allosteric activators, whereas those that decrease the protein's activity are called allosteric inhibitors. The term allostery comes from the Greek allos ...

Google previewThe SAGE Encyclopedia of Abnormal and Clinical Psychology (2017)

by Amy Wenzel

Allosteric modulators have emerged as a novel way to target receptor sites that are distinctly different from the orthosteric site where the endogenous ligands bind and modulate the effects of an orthosteric agonist. For example, positive ...

Google previewEncyclopedia of Supramolecular Chemistry (2004)

by J. L. Atwood, Jonathan W. Steed

INTRODUCTION The allosteric regulation of ligand binding to proteins is the principal regulatory mechanism in living systems on the molecular level.'1"31 The allosteric effect means the situation when the binding of one ligand at its binding ...

Google previewEncyclopedia of Neuroscience (2009)

Volume One by Larry R. Squire

Figure 6 Chemical structures of allosteric modulators of A1 receptors.

Allosteric ligand binding does not overlap with the orthosteric site, thus allowing simultaneous binding of compounds at both ...

Google previewDictionary of Biology (2014)

by Bill Indge

The separate populations are so different that they may be considered as different species Allopotric speciotion allosteric: refers to a molecule whose shape can be altered by something in its environment. This usually leads to a change in its ...

Google previewDictionary of Stem Cells, Regenerative Medicine, and Translational Medicine (2017)

by Frank J. Dye

allosteric enzymes enzymes that have two functional sites: (1) the catalytic or active site that binds substrates as ligands and (2) the ...

Google previewPolymer Science Dictionary (2017)

by Mark Alger

allosteric enzyme An enzyme at which an effector molecule may be non-covalently bound at a site other than the active site, causing a change in the activity at the active site. If the effect is inhibiting, then ...

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Photo about Allosteric


IGFR complexed with allosteric inhibitor

The Insulin-like Growth Factor 1 (IGF-1) Receptor is found on the surface of human cells and is activated by two different hormones, IGF-1 and IGF-2. IGF1R is frequently overexpressed in tumors, including melanomas, cancers of the colon, pancreas, prostate and kidney. In cancer cells, IGFR-1 contributes to the promotion of tumor growth by inhibition of the apoptosis, transformation and induction of angiogenesis. Feel free to use this image, just link to...

Photo credit: Enzymlogic

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Scrabble value of A1L1L1O1S1T1E1R1I1C3

The value of this 10-letter word is 12 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

Anagrams of ALLOSTERIC

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