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Definition of the noun Bioactivation
What does Bioactivation mean as a name of something?
- [biology] The metabolic activation of xenobiotic compounds into reactive, toxic compounds
Specialised definition of the noun Bioactivation
Glossary of pesticide
transformation of a pesticide within an organism into a more biochemically active metabolite
- synonym: toxification
Printed dictionaries and other books with definitions for Bioactivation
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by Ronald Borchardt, Edward Kerns, Michael Hageman, Dhrien Thakker, James Stevens
Avoidance of “toxicophores” or chemical structures that are likely to undergo bioactivation is a logical initial approach to lead optimization. A number of readily recognizable chemical structures have been associated with idiosyncratic reactions ...
by Heewon Lee
are listed here Metabolic bioactivation is an inherent part of the Cramer classification as many of these class III structures undergo metabolic bioactivation to form potentially toxic chemical entities: ...
UKEMS Recommended Procedures by David J. Kirkland, Margaret Fox
Exogenous activation system Bioactivation is a pre-requisite for ...
Principles of Drug Action by Francesco Clementi, Guido Fumagalli
Bioactivation is a metabolic process that increases the toxicity of the substance through the formation of unstable intermediates or metabolites with highly reactive chemical bonds capable of reacting with organic macromolecules. In particular ...
by Alvaro Puga, Kendall Wallace
Because P450-mediated bioactivation is an initial and obligatory step in chemical carcinogenesis, the interindividual variation in metabolic activity of P450s may influence subsequent steps, including dotoxification by phase IIenzymes and the ...
Encyclopedia of Toxicology (2005)
by Bruce Anderson, Ann de Peyster, Shayne C. Gad, P.J. Bert Hakkinen, Michael Kamrin, Betty Locey, Harihara M. Mehendale, Carey Pope, Lee Shugart
bioactivation of carcinogens pertains only to inhibition of chemicalinduced carcinogenesis.
by Paul M. Coates, M. Coates Paul, Marc Blackman, Marc R. Blackman, Gordon M. Cragg, Mark Levine, Jeffrey D. White, Joel Moss, Mark A. Levine
The anticancer benefits attributed to garlic are also associated with suppressed nitrosamine bioactivation. Evidence from multiple sources points to the effectiveness of garlic to block DNA alkylation, an initial step in nitrosamine carcinogenesis.
A Dictionary of Chemistry (2016)
by Richard Rennie, Jonathan Law
bioactivation. A metabolic process in which a product that is chemically reactive is produced from a relatively inactive precursor. biochemical. fuel. cell. A system that exploits biological reactions for the conversion of biomass (chemical energy) ...
by Bruce C. Wyman, L. Harold Stevenson
bioactivation likely to be bioaccumulated are not readily decomposed in either the environment or an organism and are likely to be stored in the fatty tissue. Bioaccumulation is also the progressive increase in the amount of a chemical in an ...
by S D Gangolli
Other effects Any other adverse effects Nephrotoxicity may be caused by intrarenal bioactivation of the reduced glutathione-conjugate (3). Legislation Included in Schedule 4 (Release into Air: Prescribed Substances) Statutory Instrument ...
by Henry Philippsborn
(Pharmaceutical chemistry; a medicamentous substance which needs metabolic bioactivation for turning active.) d medikamentöses Biovorprodukt n; medikamentöser Biovorläufer m f bioprécurseur m médicamenteux p bioprecursor m ...
by Heinz Mehlhorn, Horst Aspöck
regioisomer isoquine does not show any bioactivation, but the in vitro antimalarial activity is maintained. Isoquine seems to be an interesting 4-aminoquinoline for further development as antimalarial drug, not only ...
A Dictionary of Biomedicine (2010)
by John Lackie
bioactivation The conversion of a *xenobiotic substance to a more toxic or active derivative within the body. bioassay Any assay that involves using ...
by S. Gangolli
Phospholipase A2 activation may be part of the chain of causality leading from initial bioactivation to ultimate cell death in rat hepatocytes (38). Studies indicate that enzyme induction and toxicokinetics resulting from the oral administration of ...
Encyclopedia of Neuroscience (2009)
Volume One by Larry R. Squire
The mitochondrial ferrous iron catalyzes the bioactivation of protoxins (e.g., catechols, 1-methyl-4- phenyl-1,2 ...
by Victor R. Preedy, Ronald Ross Watson
anthracene bioactivation in mammary tissue.
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Video about Bioactivation
Video shows what bioactivation means. The metabolic activation of xenobiotic compounds into reactive, toxic compounds. Bioactivation Meaning. How to ...
Scrabble value of B3I1O1A1C3T1I1V4A1T1I1O1N1
The value of this 13-letter word is 20 points, but it's not an accepted word in the Official Scrabble Players Dictionary.
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