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Efudex is a drug brand, brand.


Efudex a.k.a. Fluorouracil: An antimetabolite fluoropyrimidine analog of the nucleoside pyrimidine with antineoplastic activity. Fluorouracil and its metabolites possess a number of different mechanisms of action. In vivo, fluoruracil is converted to the active metabolite 5-fluoroxyuridine monophosphate; replacing uracil, F-UMP incorporates into RNA and inhibits RNA processing, thereby inhibiting cell growth. Another active metabolite, 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate, inhibits thymidylate synthase, resulting in the depletion of thymidine triphosphate, one of the four nucleotide triphosphates used in the in vivo synthesis of DNA. Other fluorouracil metabolites incorporate into both RNA and DNA; incorporation into RNA results in major effects on both RNA processing and functions.

  • also known as 플루오로유라실, 플루로유라실, 5-FU, Флюороурацил, ฟลูโอโรยูเรซิล

Printed dictionaries and other books with definitions for Efudex

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Google previewChoice Matters (2011)

by Paul Gerhardt, Barbara Gerhardt

Efudex is a cream which had been prescribed by one doctor and it does work by attacking fastgrowing cells. The treatment takes at least two weeks and during that time there is a lot of stinging and itching as it ...

Google previewConcise Dictionary of Modern Medicine (2010)

by Joseph Segen

See Fluoride, Fluoride poisoning, Fluoride treatment, Fluorine fluorouracil 5FU, Efudex® Oncology An antimetabolite that interferes with DNA synthesis, and deprives DNA of functional thymidine; 5FU is used for bladder cancer, for terminal cancer and, topically, ...

Google previewMosby's Pocket Dictionary of Medicine, Nursing & Health Professions - E-Book (2013)

by Mosby

Efudex, a trademark for an antineoplastic (fluorouracil). EGD, abbreviation for esophagogastroduodenoscopy. egest /ijest'/ [L, egerere, to expel], to discharge or evacuate a substance from the body, especially to evacuate unabsorbed residue of foods from the intestines.—egesta, n. pl., egestive, adj. EGF, abbreviation for epidermal growth factor. egg /eg/ [ONorse], a female reproductive cell at any stage before fertilization. eglandulous /églan'dy.;l.;s/, describing an absence of glands.

Google previewConcise Dictionary of Biomedicine and Molecular Biology (2001)

by Pei-Show Juo

Efudex A trade name for fluorouracil, an anticancer ...

Google previewMosby's Dental Dictionary (2013)

by Elsevier, Mosby

n brand names: Carac, Efudex, Fluoroplex; drug class: topical pyrimidine antineoplastic; action: inhibits synthesis of DNA and RNA in susceptible cells; uses: keratosis, basal cell carcinoma. Fluothane, the brand name for halothane. fluoxetine (flŏŏok′ sətēn′), n brand name: Prozac; drug class: antidepressant; action: inhibits CNS neuron uptake ...

Google previewConcise Dictionary of Pharmacological Agents (2012)

Properties and Synonyms by I.K. Morton, Judith M. Hall

"; Efudex", Efudix"; Fluoroplex"; Fluorouracil") is a halogenated pyrimidine derivative, a cytotoxic ANTICANCERAGENT that prevents cell ...

Google previewA Dictionary of Biomedicine (2010)

by John Lackie

TN Efudex. fluoxetine A selective serotonin reuptake inhibitor (SSRI) used as an antidepressant. TN Prozac. flupentixol (flupenthixol) A typical antipsychotic neuroleptic drug that acts by antagonism of dopamine receptors D1 and D2 (as well as serotonin) and is given intramuscularly as a long-lasting depot injection in schizophrenic patients unlikely to be compliant about taking medication. TNs Depixol, Fluanxol. fluphenazine A phenothiazine derivative intended for the treatment of ...

Google previewThe Encyclopedia of Women's Reproductive Cancer (2005)

by Carol Turkington, Mitchell Edelson

(Adru- cil, Efudex). For women whose cancer remains after treatment with radiation therapy or surgery, the use of chemotherapy is meant to slow or temporarily shrink the cancer. Chemotherapy rarely ...

Google previewMosby's Medical Dictionary (2016)

by Mosby

Efudex, an antineoplastic. Brand name for fluorouracil. EGD, abbreviation for ...

Google previewMosby's Dictionary of Medicine, Nursing & Health Professions (2016)

by Mosby

Efudex, an antineoplastic.

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Scrabble value of E1F4U1D2E1X8

The value of this 6-letter word is 17 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

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