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Lorenzo's Oil


"Lorenzo's Oil": Lorenzo's Oil is a 1992 drama film directed by George Miller. It is based on the true story of Augusto and Michaela Odone, two parents in a relentless search for a cure for their son Lorenzo's adrenoleukodystrophy. The film was nominated for two Academy Awards. It was filmed primarily in Pittsburgh, Pennsylvania.


Lorenzo's oil: Lorenzo's oil is 4 parts of glyceryl trioleate and 1 part glyceryl erucate , prepared from olive oil and rapeseed oil. It is used in the investigational treatment of asymptomatic patients with adrenoleukodystrophy. The oil was formulated by Augusto and Michaela Odone after their son Lorenzo was diagnosed with the disease in 1984, at the age of five. Augusto received U.S. Patent No. 5,331,009 for the oil. The royalties he now receives are paid to the Myelin Project which he and Michaela founded to further research treatments for ALD and similar disorders. The Odones and their invention obtained widespread publicity in 1992 because of the film Lorenzo's Oil.

  • also known as 羅倫佐的油

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