For all your dictionary needs!
Spelling. Are you looking for accidie, acidize, Acridone, Pyridine, Uridine, or Viridine?
Header of acridine

Acridine

Definition of the noun Acridine

What does Acridine mean as a name of something?

noun - plural: acridines

  1. [uncountable, organic compound] A tricyclic aromatic heterocycle, dibenzopyridine, obtained from coal tar; it is used in the manufacture of dyes and drugs
  2. [countable, organic chemistry] Any of many derivatives of this compound

Explanation

  1. Acridine is an organic compound and a nitrogen heterocycle with the formula C₁₃H₉N. Acridines are substituted derivatives of the parent ring. It is a planar molecule that is structurally related to anthracene with one of the central CH groups is replaced by nitrogen. Like the related molecule pyridine and quinoline, acridine is mildly basic. It is an almost colorless solid. There are no commercial applications of acridines but at one time acridine dyes were popular. It crystallizes in needles.
  2. Acridine: A polycyclic aromatic dye with antineoplastic, antimicrobial and imaging activities. Acridine and its derivatives intercalate within DNA and RNA by forming hydrogen-bonds and stacking between base pairs resulting in DNA crosslinks and strand breaks. In addition, acridine and its derivatives are a potent inhibitor of topoisomerase II enzyme. This results in the inhibition of DNA and RNA synthesis, predominantly occurring during S phase of the cell cycle and ultimately leads to cell death.

Printed dictionaries and other books with definitions for Acridine

Click on a title to look inside that book (if available):

Google previewHeterocyclic Chemistry (1999)

Reaction with Nucleophilic Reagents: The most outstanding chemical property of acridine is that it undergoes nucleophilic attack at...

Reaction with Oxidizing Agents: Acridine is a very stable ring system towards the action of oxidizing agents.

Google previewMicrobiology with Diseases by Body System (2016)

by CTI Reviews

acridine: Acridine is an organic compound and a nitrogen heterocycle with the formula C13H9N. Acridines are substituted derivatives of the parent ring. It is a planar molecule that is structurally related to anthracene ...

Google previewOrganic Chemistry (2014)

A Mechanistic Approach by Penny Chaloner

Acridine is a nitrogen analogue of anthracene, isolated from coal tar. It is known to be a potent carcinogen and mutagen. Pyrimidine and purine are the parent compounds of the bases in nucleic acids ( Figure ...

Google previewConcepts of Genetics (2016)

by CTI Reviews

Acridine is an organic compound and a nitrogen heterocycle with the formula C13H9N. Acridines are substituted derivatives of the parent ring. It is a planar molecule that is structurally related to anthracene with one of the central CH groups is ...

Google previewEssential Genetics (2016)

by CTI Reviews

Acridine is an organic compound and a nitrogen heterocycle with the formula C13H9N. Acridines are substituted derivatives of the parent ring. It is a planar molecule that is structurally related to anthracene with one of the central CH groups is ...

Google previewGenetics, A Conceptual Approach (2016)

by CTI Reviews

acridine: Acridine is an organic compound and a nitrogen heterocycle with the formula ...

Google previewIndustrial Medicine Desk Reference (2012)

by David F. Tver

Acridine is a severe irritant to the conjunctiva of the eyes, the mucous membranes of the respiratory tract, andthe skin. Itisa powerful photosensitizer of the skin. It causes sneezing on inhalation. Yellowish discoloration of scleraand conjuctiva ...

Google previewGenetics Essentials, Concepts and Connections (2016)

by CTI Reviews

acridine: Acridine is an organic compound and a nitrogen heterocycle with the formula ...

Google previewADVANCES IN THEORETICALLY INTERESTING MOLECULES VOLUME 4 (1998)

by THUMMEL

9,10- Dihydro-10-methyl-9-methylene~acridine is an interesting borderline case. Apparently the dibenzofulvene with a nitrogen atom in the central ring would prefer to ...

Google previewGenetics, Analysis and Principles (2016)

by CTI Reviews

Acridine is an organic compound and a nitrogen heterocycle with the formula C13H9N. Acridines are substituted derivatives of the parent ring. It is a planar molecule that is structurally related to anthracene with one of the central CH groups is ...

Google previewBiocatalysis in Oil Refining (2011)

Acridine is a three-ring nitrogen heterocycle, classified as polycyclic aromatic hydrocarbons (PAHs), some of which are proposed to be human carcinogens based on the evidence of carcinogenicity in experimental animals. Acridine is ...

Google previewChemical News (1871)

\Vhen quite pure, acridine is a colourless crystalline body; fuses at 107°; boils, without decomposition, at 360°; is very difl'icultly soluble in boiling water, and not at all in cold; readily soluble in alcohol, ether, sulphide of carbon, and ...

Google previewThe Chemical News and Journal of Industrial Science (1871)

\Vhen quite pure, acridine is a colourless crystalline bod ; fuses at 107°; boils, without decomposition, at 360°; is very diflicultly soluble in boiling water, and not at all in cold; readily soluble in alcohol, ether, sulphide of carbon, and ...

Google previewThe Dictionary of Genomics, Transcriptomics and Proteomics (2015)

by Guenter Kahl

See → annealing control Acridine dye: mutagenic Any one of a series of heterocyclic compounds, including acridine and its derivatives. At low concentrations, aminoacridines (e.g. quinacrine) ...

Google previewA Dictionary of Genetics (2013)

by Robert C. King, Pamela Mulligan, William Stansfield

acridine dyes acridine (shown below ) and its derivatives. These molecules bind to double—stranded DNAs as interca — ...

Google previewElsevier's Dictionary of Vitamins and Pharmacochemistry (2006)

by Henry Philippsborn

scharf; beißend âcre acre acridine derivatives are disinfectants against purulent cocci; acridine derivatives are disinfectants against suppurating cocci (Prod.) ( Pharmaceutical technology; acridine, C13H9N, derivatives prime, material for ...

Google previewA Dictionary of Chemistry (2016)

by Richard Rennie, Jonathan Law

acridine A colourless crystalline heterocyclic compound, C12H9N; m.p. 110°C. The ring structure is ...

Google previewA Dictionary of Biology (2015)

by Elizabeth Martin, Robert Hine

acridine A chemical (see formula) that is capable of causing *frameshift mutations in the DNA sequence.

Google previewConcise Dictionary of Biomedicine and Molecular Biology (2001)

by Pei-Show Juo

Acridine (mol wt 179) A benzopyridine compound used in ...

Google previewEncyclopaedia of Occupational Health and Safety: Guides, indexes, directory (1998)

by Jeanne Mager Stellman

Acridine and benzanthrone are used as starting materials and intermediates in the manufacture of dyes. Benzanthrone is also used in the pyrotechnics industry. Propyleneimine is used in flocculants in petroleum refining and as a modifier for ...

Google previewDictionary of Toxicology (2014)

by Ernest Hodgson, Michael Roe

acridine (10-azaanthracene; dibenzo[ b,e]pyridine). CAS number 260-94-6 A compound occurring in coal tar that has been used in the manufacture of dyes and intermediates. Derivatives are used as ...

Google previewEncyclopedia of Microbiology (2009)

The sample was stained with the nucleic acid stain acridine orange, then rinsed with a solution of sodium pyrophosphate and examined by conventional epifluorescence microscopy.

Online dictionaries and encyclopedias with entries for Acridine

Click on a label to prioritize search results according to that topic:

Video about Acridine

Acridine Meaning

Video shows what acridine means. A tricyclic aromatic heterocycle, dibenzopyridine, obtained from coal tar, it is used in the manufacture of dyes and drugs.

View more videos about Acridine orange.

Scrabble value of A1C3R1I1D2I1N1E1

The value of this 8-letter word is 11 points. It is included in the first and second editions of the Official Scrabble Players Dictionary.

Anagrams of ACRIDINE

What do you get if you rearrange the letters?

See also the blanagrams of Acridine!

Share this page

Next...

Go to the usage examples of Acridine to see it in context!


Privacy Policy | Cookies Policy
Keyword Tool | Romanian-English Dictionary