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Altretamine

Definition of the noun Altretamine

What does Altretamine mean as a name of something?

noun

  1. A particular antineoplastic drug.

Explanation

Altretamine: A synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage.

Printed dictionaries and other books with definitions for Altretamine

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Google previewDrugs During Pregnancy and Lactation (2011)

Treatment Options and Risk Assessment by Christof Schaefer, Paul W.J. Peters, Richard K Miller

Altretamine is an oral drug used to treat ovarian cancer, which was approved by the FDA in 1990.

Google previewOncologic Therapies (2011)

by Everett E. Vokes, Harvey M. Golomb

Hexamethylamine (Altretamine) Altretamine is an alkylating agent used both as a single agent and in combined regimen for the treatment of primary or refractory ovarian cancer [110]. It is administered orally at a dose of 260 mg/m2 per ...

Google previewPharmacology for Massage Therapy (2005)

by Jean M. Wible

Altretamine Common Drug Na altretamine: Hexalen Altretamine is a synthetic cytotoxic antineoplastic drug that is used as palliative treatment for patients with ovarian cancer. Adverse Reactions to Interferons • Blood toxicity occurs in up to half ...

Google previewConsumers Guide to Cancer Drugs (2004)

by Gail M. Wilkes, Terri B. Ades

Altretamine is a capsule taken by mouth. The dose depends upon your size. The daily dose is split into 4 divided doses, taken after meals and at bedtime. Altretamine is taken for 14 or 21 days every 4 weeks (28 days). The dose may need to ...

Google previewCRC Desk Reference of Clinical Pharmacology (1997)

by Manuchair Ebadi

Altretamine is a sym-triazine cytotoxic agent which is structurally related to the alkylating agents. Its precise mechanism of action is unknown but hydroxymethyl intermediates in the metabolism process are possibly the reactive species, and ...

Google previewPharmacology for Health Professionals (2010)

by Bronwen Bryant, Kathleen Knights

Altretamine is a cytotoxic agent for the palliative treatment of persistentorrecurrent ovarian cancer. Its mechanism of action is unknown, although chemically it resembles the alkylatingagents. Clinically, however, itis effective for ...

Google previewDesk Reference of Clinical Pharmacology, Second Edition (2007)

by Manuchair Ebadi

ALTRETAMINE (Hexalen) Altretamine is an ethyleneimine alkylating agent that is indicated as a palliative therapy of refractory ovarian cancer following treatment failure with a cisplatin- or alkylating agent-based combination. Its mechanism of ...

Google previewDrug Interactions Analysis and Management 2010 (2016)

Pharmaceutical sciences, Pharmaceutical sciences by CTI Reviews

Altretamine: Altretamine is an antineoplastic agent. It was approved by the FDA in 1990. Aminoglutethimide: Aminoglutethimide is an antisteroid drug ...

Google previewIntroduction to Pharmacology (2016)

Pharmaceutical sciences, Pharmacology by CTI Reviews

Altretamine: Altretamine is an antineoplastic agent. It was approved by the FDA in 1990. Uses It is usedtotreat refractory ovarian cancer.It is not considered afirstline treatment, but it can be usefulas salvage therapy. It alsohas the advantage of ...

Google previewPharmacology, Connections to Nursing Practice (2016)

by CTI Reviews

Altretamine is an antineoplastic agent. It was approved by the FDA in ...

Google previewFocus on Nursing Pharmacology (2016)

by CTI Reviews

Altretamine: Altretamine is an antineoplastic agent. It was approved by the FDA in 1990. Uses It is used totreat refractory ovariancancer. Arsenic trioxide: Arsenic trioxideis the inorganic compound withthe formulaAs 2 O 3 . This commercially ...

Google previewPrinciples of Pharmacology, The Pathophysiologic Basis of Drug Therapy (2016)

by CTI Reviews

Altretamine: Altretamine is an antineoplastic agent. It was approvedbythe FDAin 1990. Estramustine: Estramustine is a chemotherapy agent used to treat prostate cancer.

Google previewPearson Reviews and Rationales, Comprehensive Review for NCLEX-RN (2016)

Nursing, Nursing by CTI Reviews

Altretamine: Altretamine is an antineoplastic agent. Itwas approved by the FDAin 1990. Uses It is used totreat refractory ovarian cancer. Angiogenesis inhibitor: An angiogenesisinhibitor is a substance that inhibits the growth of new blood ...

Google previewPharmacology for Nursing Care (2013)

by Richard A. Lehne

Altretamine (Hexamethylmelamine) Altretamine [Hexalen], formerly known as hexamethylmelamine, is indicated for palliative therapy of persistent or recurrent ovarian cancer Altretamine is a prodrug that is converted to active metabolites in ...

Google previewLehne's Pharmacology for Nursing Care (2014)

by Jacqueline Burchum, Laura Rosenthal

Altretamine is a prodrug that is converted to active metabolites in the body. As with procarbazine and dacarbazine, the active metabolites have alkylating activity. However, the precise mechanism of cell kill has not been established.

Google previewPerry's The Chemotherapy Source Book (2012)

by Michael Clinton Perry, Donald C. Doll, Carl E. Freter

Altretamine is a synthetic antineoplastic s-triazine derivative. Of 76 previously treated ovarian cancer patients, 9% developed elevated transaminases after receiving single-agent altretamine therapy. It was not mentioned if ...

Google previewThe Chemotherapy Source Book (2008)

by Michael Clinton Perry

Altretamine is a synthetic antineoplastic s-triazine derivative. Of 76 previously treated ovarian cancer patients, 9% developed elevated transaminases after receiving single-agent altretamine therapy. It was not mentioned if these elevations ...

Google previewPharmaceutical Manufacturing Encyclopedia, 3rd Edition (2013)

by William Andrew Publishing

Altretamine Rhone Poulenc W. Germany 1982 Raw Materials Hexamethylolmelamine-Hexamethyl Ether ...

Google previewLewis' Dictionary of Toxicology (1998)

by Robert Alan Lewis

altretamine. hexamethylene. cyclohexane. hexamethylenebis(trimethylammonium)chloride. hexamethonium chloride. hexamethylmelamine. altretamine. hexan-2,5-dione. a ...

Google previewCancer Dictionary (2004)

by Henry A. Rose

altretamine An anticancer drug that belongs to the ...

Google previewConcise Dictionary of Modern Medicine (2010)

by Joseph Segen

Bends, Decompression sickness altitude sickness Mountain sickness, see there altretamine Hexalen Oncology An alkylating anticancer agent. See Chemotherapy aluminum A metallic element–atomic number 13; atomic weight 26.98 ...

Google previewSaunders Comprehensive Veterinary Dictionary (2011)

by Virginia P. Studdert, Clive C. Gay, Douglas C. Blood

altretamine [al-tret'-mēn] an alkylating agentused as and antineoplastic,similar to tretamine. altricial saidofsome speices ofbirds and mammals that givebirthtorelatively immature young witheyesthat are notopen ...

Google previewConcise Pocket Medical Dictionary (2015)

by UN Panda

Altretamine An alkylating agent for ovarian cancer. Aluminium A white silvery ...

Google previewMosby's Dictionary of Medicine, Nursing and Health Professions - Australian & New Zealand Edition (2014)

by Peter Harris, Sue Nagy, Nicholas Vardaxis

altretamine, an antineoplastic agent structurally related to the alkylating agents but thought to have a different mode of action. INDICATIONS It is prescribed either as a single agent or in combination with other ...

Google previewMosby's Pocket Dictionary of Medicine, Nursing & Health Professions - E-Book (2013)

by Mosby

altretamine, an antineoplastic agent used for the palliative treatment of recurrent, persistent ovarian cancer. altruism /al'trfi-iz' 9m/, a.

Google previewThe SAGE Encyclopedia of Pharmacology and Society (2015)

by Sarah E. Boslaugh

The different kinds of alkylating agents include ethyleneimines (thiotepa and altretamine), triazines (dacarbazine and temozolomide), alkyl sulfonates ( busulfan), nitrosoureas (streptozocin, carmustine, and lomustine), and nitrogen mustards ...

Google previewMosby's Dental Dictionary (2013)

by Elsevier, Mosby

altretamine (altret ′əmēn′), n brand name: Hexalen; drug class: antineoplastic; action: products of ...

Google previewCRC Dictionary of Agricultural Sciences (2001)

by Robert Alan Lewis

altretamine. tris(l- aziridinyl)phosphine sulfide. thiotepa. Trisetum flavescens (golden oats; yellow oats; yellow oat grass). a tall grass (Family Gramineae). growing to nearly 1 m in ...

Google previewThe Encyclopedia of Women's Reproductive Cancer (2005)

by Carol Turkington, Mitchell Edelson

Hexalen See ALTRETAMINE. hexamethylmelamine See ALTRETAMINE. Hycamtin Appendix IV 267.

Google previewEncyclopedia of Cancer (2011)

by Manfred Schwab

Nab-paclitaxel Melphalan Altretamine ...

Google previewMosby's Medical Dictionary (2016)

by Mosby

acid See altretamine. hexylcaine hydrochloride /hek′′silkān/, a local anesthetic for ...

Google previewMosby's Dictionary of Medicine, Nursing & Health Professions (2016)

by Mosby

acid See altretamine. hexylcaine hydrochloride /hek′′silkān/, a local anesthetic for ...

Google previewConcise Dictionary of Pharmacological Agents (2012)

Properties and Synonyms by I.K. Morton, Judith M. Hall

Hexaalen" = altretamine. hexabiscarbacholine * carbolonium bromide. hexachloroethane is an ANTHELMINTIC, used by dispersion in pyrotechnics and chemical smokes. hexachlorophane (BAN] (hexachlorophene (INN]: Dermalex"; Septisol" ...

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Scrabble value of A1L1T1R1E1T1A1M3I1N1E1

The value of this 11-letter word is 13 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

Anagrams of ALTRETAMINE

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