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Anandamide

Definition of the noun Anandamide

What does Anandamide mean as a name of something?

noun

  1. [biochemistry] The ethanolamide of arachidonic acid; it binds to, and activates cannabinoid receptors in the brain

Explanation

Anandamide, also known as N-arachidonoylethanolamine or AEA, is an endogenous cannabinoid neurotransmitter. The name is taken from the Sanskrit word ananda, which means "joy, bliss, delight", and amide. It is synthesized from N-arachidonoyl phosphatidylethanolamine by multiple pathways. It is degraded primarily by the fatty acid amide hydrolase enzyme, which converts anandamide into ethanolamine and arachidonic acid. As such, inhibitors of FAAH lead to elevated anandamide levels and are being pursued for therapeutic use.

Printed dictionaries and other books with definitions for Anandamide

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Google previewMarijuana Medical Handbook (2008)

Practical Guide to Therapeutic Uses of Marijuana by Dale Gieringer, Ed Rosenthal

The principal endocannabinoid is called anandamide (after the Sanskrit word for bliss). Anandamide breaks down more rapidly than THC and seems to interact less strongly with the CB1 receptor. Anandamide and its receptors are found in ...

Google previewFundamental Neuroscience (2013)

by Larry R. Squire

Anandamide is a fatty acid amide and is the best characterized of the ECs. However, the synthesis of anadamide can be accomplished through alternative pathways, and it is unclear which of these multiple synthetic routes predominates in ...

Google previewPrinciples of Biology: Animal Systems: A Tutorial Study Guide (box set) (2015)

by Nicoladie Tam

Anandamide is an endocannabinoid that is naturally synthesized on demand in the brain and in the immune system. It binds with the classical CB1 cannabinoid receptors in the brain. It is involved in producing the blissful, pleasurable ...

Google previewTextbook of Gastroenterology, 2 Volume Set (2011)

by Tadataka Yamada

Anandamide is an endogenous can-nabinoid and belongs to a family that has been shown to modulate hepatic fibrogenesis both in vitro and in vivo. Endocannabinoids bind to CB1 and CB2 receptors, which exert powerful profibrogenic and ...

Google previewCounseling Boys and Young Men (2012)

by Suzanne Degges-White, PhD, LMHC-IN, LPC-NC, NCC, Bonnie Colon, LMHC, NCC, NCSC

One such compound is called anandamide (Sanskrit for bliss), ...

Google previewCannabinoids (2004)

by Vincenzo Di Marzo

Anandamide is an amide and belongs to the 20:4, n-6 series. Mono substitution of the amide is a requirement for activity. Substitution by an alkyl, fluoroalkyl or a hydroxyalkyl increases activity with a two or three carbon chain being optimal.

Google previewThe Basal Ganglia VII (2012)

by Louise F.B. Nicholson, Richard L.M. Faull

Structurally, anandamide is an eicosanoid consisting of a 20 carbon fatty-acid ( arachidonic acid) coupled to ethanolamine through an amide linkage, whereas 2arachidonylglycerol is an arachidonylester (Stella et al., 1997). There is strong ...

Google previewHoles Essentials of Human Anatomy and Physiology (2016)

by CTI Reviews

Anandamide is an endogenous cannabinoid neurotransmitter found in animal and human organs, especially in the brain. It was isolated and its structure was first described by Czech analytical chemist Lumír OndÅTMej HanuÅ¡ and American ...

Google previewCommunication in Plants (2006)

Neuronal Aspects of Plant Life by F. Baluška, František Baluška, Stefano Mancuso, Dieter Volkmann

b Anandamide is an N-acylethanolamine (NAE) with a 20- carbon ...

Google previewPharmacology for Chemists (2007)

by Joseph G. Cannon

Anandamide is a ligand for both types of receptors. Both CB1 and CB2 receptors are negatively coupled G protein-linked, leading to inhibition of the catalytic activity of adenylate cyclase. The physiological role(s) of cannabinoid receptors and ...

Google previewDrug Use, Misuse and Abuse (2014)

by Cecile A. Marczinski

Anandamide is an inhibitory lipid neurotransmitter found in both the central and peripheral nervous systems. Anandamide binds to cannabinoid receptors, which are also sensitive to THC, the primary psychoactive cannabinoid found in ...

Google previewEncyclopedia of the Neurological Sciences (2014)

Soon after, two endogenous ligands for the cannabinoid receptors were also identified, namely arachidonylethanolamide (anandamide) and 2-arachydonyl glycerol (2-AG). Anandamide shows selectivity for binding at the CB1 receptor, ...

Google previewEncyclopedia of Mind Enhancing Foods, Drugs and Nutritional Substances, 2d ed. (2015)

by David W. Group

Anandamide Discovered in1992 by Raphael Mechoulam,it is an endocannabinoid,or chemical producedby the body that is similar to THC, the psychoactive ingredient in marijuana. Effects: Identified in2004by neuroscientist Arne Dietrich of ...

Google previewEncyclopedia of Movement Disorders (2010)

Several endocannabinoids have now been described, but arachydonoyl ethanolamide (anandamide) and 2-arachidonylglycerol (2-AG) are the best characterized. These are ecosanoid phospholipids produced on receptor- mediated demand ...

Google previewA Consumer's Dictionary of Cosmetic Ingredients, 7th Edition (2009)

Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics and Cosmeceuticals by Ruth Winter

the neurotransmitter anandamide is one of the active chemicals within the extract, which produces a feeling of euphoria and relaxation. The Switzerland-based company. which is employing one of the ...

Google previewA Dictionary of Psychology (2015)

by Andrew M. Colman

anandamide with the *dependent variable, and analyses the portion of the variance in the dependent variable explained by one or more *independent variables excluding the extraneous variable. In psychology, it is often used to suppress ...

Google previewEncyclopedia of Genetics, Genomics, Proteomics, and Informatics (2008)

by George P. Rédei

Anandamide also protect the central nervous ...

Google previewThe Dictionary of Cell and Molecular Biology (2012)

by John M. Lackie

Bind to the cannabinoid receptors and mimic actions of endogenous agonists anandamide and palmitoyl ethanolamine. cannabinoid receptors G-protein- coupled receptors for cannabinoids (and endogenous agonists such as anandamide).

Google previewEncyclopedia of Substance Abuse Prevention, Treatment, and Recovery (2009)

by Gary L. Fisher, Nancy A. Roget

The neurotransmitter, anandamide, has been suggested to be of importance during the early stages of pregnancy. This neurotransmitter, not discovered until 1995, acts on the limbic system and has been implicated as affecting emotions, ...

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Scrabble value of A1N1A1N1D2A1M3I1D2E1

The value of this 10-letter word is 14 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

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