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The Lems was an English electric car manufactured by the London Electromobile Syndicate in London from 1903 to 1904. The two-seater runabout claimed to run 40 miles on a single charge and reach a top speed of 12 mph. It was sold for 180 guineas.


LEMS a.k.a. Lambert–Eaton myasthenic syndrome is a rare autoimmune disorder that is characterized by muscle weakness of the limbs. It is the result of an autoimmune reaction in which antibodies are formed against presynaptic voltage-gated calcium channels, and likely other nerve terminal proteins, in the neuromuscular junction. The prevalence is 3.4 cases per million. Around 60% of those with LEMS have an underlying malignancy, most commonly small cell lung cancer; it is therefore regarded as a paraneoplastic syndrome.

Printed dictionaries and other books with definitions for Lems

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Google previewEssential Neuropharmacology (2015)

The Prescriber's Guide by Stephen D. Silberstein, Michael J. Marmura, Hsiangkuo Yuan

Unlike MG, LEMS is a presynaptic disorder of neuromuscular transmission. LEMS is an autoimmune disease with antibodies directed against the voltage- gated calcium channels. LEMS is usually associated with small-cell lung cancer Not ...

Google previewAgent-Based Modelling of Social Networks in Labour–Education Market System (2015)

by Alexander Tarvid

Because ABM is a natural method of modelling CASs, an economy is a CAS and LEMS is a part of the economy. There are now three...

Google previewPhysical Medicine and Rehabilitation Q&A Review (2013)

by Lyn D. Weiss, MD, Harry J. Lenaburg, MD, Jay M. Weiss, MD

LEMS is a disorder of neuromuscular transmission due to an autoimmune response against the active sites on the presynaptic membrane. Botulism is a disorder of neuromuscular transmission caused by Clostridium botulinum toxins blocking ...

Google previewNetter's Concise Neurology Updated Edition (2016)

by Karl E. Misulis, Thomas C. Head

LAMBERT-EATON MYASTHENIC SYNDROME (LEMS) Description • Autoimmune disease affecting the neuromuscular junction • Associated with cancer, especially small cell lung cancer Pathophysiology • LEMS is a prototypic paraneoplastic ...

Google previewDiagnostic Criteria in Autoimmune Diseases (2008)

by Yehuda Shoenfeld, Ricard Cervera, M. Eric Gershwin

LEMS is an autoimmune disorder of the peripheral nervous system in which autoantibodies to specific subtypes of VGCCs...

LEMS is a disorder of proximal muscle weakness and autonomic dysfunction, for example abnormal sweating, dry ...

Google previewEmergency Medicine (2012)

Clinical Essentials (Expert Consult -- Online) by James G. Adams

LEMS is an autoimmune presynaptic disorder of the NMJ. IgG autoantibodies bind to the presynaptic calcium channels, thereby inhibiting entry of calcium into the cell during depolarization. The net effect is decreased release of ACh and ...

Google previewClinical Neurology of the Older Adult (2008)

by Joseph I. Sirven, Barbara L. Malamut

Etiology LEMS is an antibody-mediated immune disorder in which antibodies directed against P/Q-type VGCCs in the motor nerve...

Google previewReligion and Prevention in Mental Health (2014)

Research, Vision, and Action by Robert E Hess, Kenneth I Maton, Kenneth Pargament

lems is that they reflect a lack of integration in individual lives among aspects of self, others, community, and God. Optimal preventive efforts thus invite individuals into processes which (from the religious perspective, through faith and with ...

Google previewThe Alzheimer's Solution

How Today's Care Is Failing Millions-and How We Can Do Better by Kenneth S. Kosik, Ellen Clegg

REAPPRAISING THE PROBLEM OF COGNITION IN ELDERS Failure to attend to cognitive health and disregard for cognitive prob- lems is a threat to human health. The underlying reasoning of organi- zations such as IPPNW, PHR, and ...

Google previewWriting and Responsibility (2005)

by Carl Tighe

One of the main prob- lems is that PC seeks to introduce political considerations into purely literary matters. True, literature is political, and cannot avoid being part of the way ...

Google previewData Just Right (2013)

Introduction to Large-Scale Data & Analytics by Michael Manoochehri

However, a common fallacy oflarge data analysis prob- lems is that you require an entire corpus of data to make decisions or arrive at conclu- sions. Indeed, one of the cornerstones of statistical analysis is to provide quantitative evidence that ...

Google previewComprehensive Review in Clinical Neurology (2012)

A Multiple Choice Question Book for the Wards and Boards by Esteban Cheng-Ching, Lama Chahine, Eric P. Baron, Alexander Rae-Grant

LEMS is a disorder of neuromuscular transmission characterized by a reduced release of acetylcholine, and antibodies to presynaptic voltage-gated calcium channels. LEMS is frequently detected as a paraneoplastic syndrome associated ...

Google previewSubjective Consciousness (2009)

A Self-Representational Theory by Uriah Kriegel

The fact that there survives a further problem that goes beyond the easy prob- lems is an expression of the fact that there is more to consciousness than the bundle of functions associated with it. That is, it is an expression of the fact that there is ...

Google previewEssentials of Neuroanesthesia (2017)

by Hemanshu Prabhakar

LEMS is a rare presynaptic disorder of neuromuscular transmission in which quantal release of ACh is impaired. The disease is characterized by proximal muscle weakness and depressed tendon reflexes. In 40–60% of patients with LEMS, ...

Google previewEncyclopedia of the Neurological Sciences (2014)

LEMS patients without a detectable SCLC, it is difficult to exclude an occult tumor in these few patients. The presence of SOX antibodies does not influence survival in SCLC patients, and no pathogenic role for the antibodies has been reported ...

Google previewThe Encyclopedia of Autoimmune Diseases (2003)

by Dana K. Cassell, Noel R. Rose

Lambert-Eaton myasthia syndrome (LEMS) A rare disorder with symptoms very similar to those of MYASTHENIA GRAVIS. Muscle weakness is associated with disturbed communication between nerves and muscles. Unlike myasthenia gravis ...

Google previewEncyclopedia of Psychological Assessment (2002)

by Rocio Fernandez-Ballesteros

Since it was argued that the right cerebral hemisphere is associated with the processing of visual information and that the spontaneous lateral eye movements (LEMs) are under the control of the counter-lateral hemisphere, it was claimed that ...

Google previewEncyclopedia of the Eye (2010)

by Joseph Besharse, Reza Dana

systemic botulism, neuromuscular blocking agents, and the LambertEaton myasthenic syndrome (LEMS), which is due to the impaired release of acetylcholine secondary to autoimmune attack on presynaptic P/Q voltagegated calcium ...

Google previewInternational Encyclopedia of Systems and Cybernetics (2004)

by Charles François

lems. which. arised. from. some. theoretical. formentarity. of sexes (rigid relations), came well established and generally recog -. Context neglect is a general and sure-brand recipe for unsatisfactory based research, ...

Google previewSimiles Dictionary (2013)

by Elyse Sommer


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Scrabble value of L1E1M3S1

The value of this 4-letter word is 6 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

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