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Terfenadine

Definition of the noun Terfenadine

What does Terfenadine mean as a name of something?

noun

  1. An antihistamine drug formerly used to treat allergic conditions, superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia.

Explanation

Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was brought to market by Hoechst Marion Roussel and marketed under various brand names, including Seldane in the United States, Triludan in the United Kingdom, and Teldane in Australia. According to its manufacturer, terfenadine had been used by over 100 million patients worldwide as of 1990. It was superseded by fexofenadine in the 1990s due to the risk of a particular type of disruption of the electrical rhythms of the heart.

Printed dictionaries and other books with definitions for Terfenadine

Click on a title to look inside that book (if available):

Google preview1000 Questions and Answers from Kumar & Clark's Clinical Medicine (2011)

by Parveen Kumar, Michael L Clark

Interaction between the antihistamine terfenadine means that the two should never be given ...

Google previewAdverse Drug Interactions (2016)

A Handbook for Prescribers, Second Edition by Lakshman Delgoda Karalliedde, Simon Clarke, Ursula Gotel nee Collignon, Janaka Karalliedde

For example, terfenadine is an IKr blocker but it is nearly completely biotransformed by the CYP3A enzyme system to the noncardioactive fexofenadine before entering the ...

Google previewPrinciples of Pharmacology, The Pathophysiologic Basis of Drug Therapy (2016)

by CTI Reviews

Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was brought to market by Hoechst Marion Roussel (now SanofiAventis) and marketed under various brand names including Seldane in the United States, ...

Google previewLiver Disorders in Childhood (2013)

by Alex P. Mowat

Terfenadine is an antihistamine with mild antipruritic effects.

Google previewImmune Metabolism in Health and Tumor (2017)

by Bin Li, Fan Pan

Terfenadine is a histamine receptor H1 antagonist, which can prevent VEGF secretion from mast cells in hypoxic microenvironment and induce ROS- mediated apoptosis and autophagy of melanoma cells [247]. Simvastatin specifically inhibits ...

Google previewPharmacotherapy Principles and Practice (2016)

by CTI Reviews

Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was brought to market by Hoechst Marion Roussel (now SanofiAventis) and marketed under various brand names including Seldane in the United States, ...

Google previewHuman Drug Metabolism , An Introduction (2016)

Pharmaceutical sciences, Pharmaceutical sciences by CTI Reviews

Terfenadine: Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was brought to market by Hoechst Marion Roussel (now SanofiAventis) and marketed under various brandnames including Seldane inthe ...

Google previewRespiratory Care Pharmacology (2016)

by CTI Reviews

Terfenadine: Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was broughttomarket by Hoechst Marion Roussel (now SanofiAventis) and marketed under variousbrand names including Seldane in the ...

Google previewOral Controlled Release Formulation Design and Drug Delivery (2011)

Theory to Practice by Hong Wen, Kinam Park

For example, the approved antihistamine terfenadine is a prodrug used for the treatment of allergic rhinitis and has been replaced by the active metabolite fexofenadine that shows less cardiac side effects [6]. Fexofenadine has become the ...

Google previewPharmacology for Podiatrists (2008)

by Dr. Rae Morgan, Dr. Margaret Johnson

Terfenadine is an antihistamine prodrug, which must be metabolised to an active metabolite, fexofenadine, by cytochrome P-450 before it can produce its pharmacological effect. The inhibition of cytochrome P-450 by antibacterial drugs such ...

Google previewPharmaceutical Manufacturing Encyclopedia, 3rd Edition (2013)

by William Andrew Publishing

- Common Name: Terfenadine Structural Formula: Trade Name Manufacturer Country Year ...

Google previewConcise Dictionary of Modern Medicine (2010)

by Joseph Segen

terfenadine. Seldane® A nonsedating antihistamine used1 for allergy and viral upper respiratory tract infections Adverse effects Arrhythmias–eg, torsades de pointes2; should not be combined.

Google previewMosby's Dictionary of Medicine, Nursing and Health Professions - Australian & New Zealand Edition (2014)

by Peter Harris, Sue Nagy, Nicholas Vardaxis

tenoxicam tamoxifen Tequin Ticlid terazosin doxazosin terazosin prazosin terbinafine terfenadine terfenadine terbinafine thiamine Tenormin thioridazine thyroxine thyroxine thioridazine Ticlid Tequin tobramycin gentamicin Tofranil Topamax ...

Google previewConcise Dictionary of Pharmacological Agents (2012)

Properties and Synonyms by I.K. Morton, Judith M. Hall

Terfenor" = terfenadine. terguride (INN] (transdihydrolisuride) is an ergoline, or ergot alkaloid derivative, with (D2) partial DOPAMINE RECEPTORAGONIST activity, activity as an ANTiPARKINSONIAN AGENT and PROLACTIN RELEASE ...

Google previewConcise Pocket Medical Dictionary (2015)

by UN Panda

Terfenadine H1 receptor blocker, antiallergic ...

Google previewEncyclopedia of Human Nutrition, Four-Volume Set (2005)

by Lindsay Allen, Andrew Prentice

magnesium; chelation by polyvalent cations Decreases absorption Decreases bioavailability Increases urinary losses; decreases Continued Table 2 Continued Drug Class Food/nutrient Effect/mechanism Terfenadine Antihistamine Food.

Google previewSaunders Comprehensive Veterinary Dictionary (2011)

by Virginia P. Studdert, Clive C. Gay, Douglas C. Blood

terfenadine [t r- fen' ...

Google previewThe Complete Encyclopedia of Medicine & Health (2006)

by J. P. Schadé

Terfenadine A proprietary, prescription-only antihistamine drug. It can be used for the symptomatic relief ...

Google previewEncyclopedia of Neuroscience (2009)

Volume One by Larry R. Squire

In the 1980s, rather by chance, a number of less CNS-penetrating H1 blockers were found (terfenadine, cetirizine, and loratadine are examples); these compounds led to a new class of a second-generation non-sleep-inducing (or less ...

Google previewMosby's Dental Dictionary (2007)

by Elsevier, Mosby

terfenadine (terfen′de ̄n′), n brand name: Seldane; drug class: antihistamine; action: acts on blood vessels and gastrointestinal and respiratory systems by competing with histamine for peripheral H1 receptor ...

Google previewEncyclopedia of Cancer (2008)

by Manfred Schwab

Compounds used to chemosensitize P-gp-mediated MDR tumor cells Quinidine, amiodarone, propafenone Antibiotics Cephalosporins Antihistaminics Terfenadine, azelastine Antihypertensive Reserpine Antimalarials Quinine, quinacrine, ...

Online dictionaries and encyclopedias with entries for Terfenadine

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Video about Terfenadine

Terfenadine Meaning

Video shows what terfenadine means. An antihistamine drug formerly used to treat allergic conditions, superseded by fexofenadine in the 1990s due to the risk ...

Scrabble value of T1E1R1F4E1N1A1D2I1N1E1

The value of this 11-letter word is 15 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

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