For all your dictionary needs!
Index. Are you looking for terms starting with AML?
Header of AML

Examples of AML

Sentences

94 examples:

One area of specific focus is that of Anti-Money Laundering (AML).
(Forbes - Technology, )

This could lead to a new therapy for AML and possibly other cancers.
(Science Daily - News, )

This analysis overviews the late-stage AML pipeline and the changing AML market.
(Nature Reviews Drug Discovery, )

The FDA approved Novartis's FLT3 inhibitor midostaurin for acute myeloid leukaemia (AML).
(Nature Reviews Drug Discovery, )

AML occurs mainly in older patients and has a three-year survival rate of 5 to 15 percent.
(Science Daily - News, )

Acute myeloid leukemia (AML) is an aggressive cancer known for drug resistance and relapse.
(Science Daily - News, )

Acute myeloid leukemia (AML) refers to a group of disorders that are also known as blood cancer.
(Science Daily - News, )

Despite improved therapy, only one out of every two adult patients survive acute myeloid leukemia (AML).
(Science Daily - News, )

The study suggests that targeting this protein could be an effective treatment for certain AML patients.
(Science Daily - News, )

Researchers have developed an automated 'debugging' approach called Adaptive Multimodal Bug Localisation (AML).
(Science Daily - News, )

The mechanism that gene MN1 uses to cause an aggressive AML subtype is better understood thanks to new research.
(Science Daily - News, )

The management of acute myeloid leukaemia (AML) in young adult patients has not changed much over the past 30 years.
(Nature Reviews Clinical Oncology, )

Acute myeloid leukaemia (AML) is a heterogeneous disease that is, in general, associated with a very poor prognosis.
(Nature Reviews Clinical Oncology, )

MDS can lead to acute myeloid leukemia (AML), a fast-spreading blood cancer that can be deadly if not treated promptly.
(Science Daily - News, )

A promising new approach to the treatment of acute myeloid leukemia (AML) has been discovered by a team of researchers.
(Science Daily - News, )

Acute myeloid leukemia (AML) is actually an umbrella term for 11 distinct subtypes of the illness, new research has revealed.
(Tech Times - Health, )

The authors suggest the research may point to new paradigms in both the diagnosis and treatment of aggressive cancers, like AML.
(Science Daily - News, )

STAT3 is a transcription factor involved in cell survival and immunosuppression, and is implicated in acute myeloid leukaemia (AML).
(Nature Reviews Clinical Oncology, )

In an effort to uncover new treatment strategies, researchers have discovered that a cell surface molecule known as CD98 promotes AML.
(Science Daily - News, )

Ansley Riedel was just 10 months old when she was diagnosed with acute myeloid leukemia (AML) – a cancer of the blood and bone marrow.
(Fox News - Health, )

AML is an aggressive disease of malignant immature blood cells which, if left untreated, almost always causes the death of the affected patient.
(Science Daily - News, )

The study raises hopes that current efforts to target this signaling protein could be a successful strategy to treat AML and other blood cancers.
(Science Daily - News, )

Gentner et al. identified a prognostic microRNA (miRNA) signature from leukaemia stem cells (LSCs) in human acute myeloid leukaemia (AML) samples.
(Nature Reviews Cancer, )

Here, the authors report frequent CDC25C mutations in FPD/AML patients and suggest that this gene may influence malignant transformation in FPD/AML.
(Nature Communications, )

Refractoriness to induction chemotherapy and relapse after achievement of remission are the main obstacles to cure in acute myeloid leukaemia (AML).
(Nature, )

The origin of relapse in acute myeloid leukaemia (AML) is thought to be due to drug-promoted mutagenesis or to the selection of drug-resistant cells.
(Nature Reviews Cancer, )

A new molecular pathway that is required for acute myeloid leukemia (AML) development has been identified by a team of researchers for the first time.
(Science Daily - News, )

EXCLUSIVE: Alfie Gregory, four, from Nottingham, was first diagnosed with acute myeloid leukaemia (AML) in March 2014, just before his second birthday.
(Daily Mail - Femail, )

Our results suggest the BCAA–BCAT1–αKG pathway as a therapeutic target to compromise leukaemia stem-cell function in patients with IDHWTTET2WT AML.
(Nature, )

Responses of acute myeloid leukaemia (AML) patients to cytarabine (Ara-C)-based therapies are often short lived with a median overall survival of months.
(Nature, )

A new drug shows promise in its ability to target one of the most common and sinister mutations of acute myeloid leukemia (AML), according to researchers.
(Science Daily - News, )

In a Phase II clinical trial in poor prognosis AML, ribavirin monotherapy yielded promising responses including remissions; however, all patients relapsed.
(Nature, )

Lechman, Gentner et al. identified a prognostic microRNA (miRNA) signature from leukaemia stem cells (LSCs) in human acute myeloid leukaemia (AML) samples.
(Nature Reviews Cancer, )

Feb. 9 (UPI) -- Researchers used a computer to accurately predict which patients with acute myelogenous leukemia, or AML, will relapse or go into remission.
(UPI - Health News, )

The study demonstrates the validity of using approximate maximum likelihood (AML) algorithms to determine the direction of arrival (DOA) of birdsong sources.
(Science Daily - News, )

Researchers have figured out a way to prevent MYB, one of the most potent cancer-aiding proteins, from activating genes in AML, an aggressive form of leukemia.
(Science Daily - News, )

The FDA approved the Novartis AG's Rydapt on April 28. The drug is targeted toward AML patients and the FDA lists it for $22,500 for an average 42-day treatment.
(Tech Times - Health, )

They show that use of their approach could reduce the number of hematopoietic cell transplants in patients with AML by up to 25% while maintaining survival rates.
(Nature Genetics, )

AML gleans debugging hints from both bug reports and test cases, and it performs a statistical analysis to pinpoint program elements that are likely to contain bugs.
(Science Daily - News, )

Researchers show that inhibiting the METTL3 gene destroys AML cells without harming non-leukemic blood cells and reveals why METTL3 is required for AML cell survival.
(Science Daily - News, )

Blue Tobin, from Dover, was diagnosed with acute myeloid leukaemia (AML) aged two and doctors were about to give up when they devised a 'unique' treatment to save him.
(Daily Mail - Femail, )

A tumor suppressor protein thought to prevent acute myeloid leukemia (AML) can actually promote a particularly deadly form of the disease, researchers have discovered.
(Science Daily - News, )

A mechanism that enables the development of resistance to Acute Myeloid Leukemia (AML) anticancer drugs, thereby leading to relapse, has been identified by researchers.
(Science Daily - News, )

Targeting exhausted immune cells may change the prognosis for patients with acute myeloid leukemia (AML) relapse after a stem cell transplant, according to researchers.
(Science Daily - News, )

The standard of care for the treatment of acute myeloid leukaemia (AML) has changed little for decades, but there are now a number of interesting agents in development.
(Nature Reviews Drug Discovery, )

Multiple cytogenetic and molecular abnormalities that characterize different forms of AML have been used to better prognosticate patients and inform treatment decisions.
(Nature Reviews Clinical Oncology, )

BCAT1high AML showed robust enrichment for leukaemia stem-cell signatures, and paired sample analysis showed a significant increase in BCAT1 levels upon disease relapse.
(Nature, )

Treatments aimed to restore EZH2 expression in relapsed AML patients have shown clinical efficacy and constitute a viable approach to re-sensitize tumors to chemotherapy.
(Nature Medicine, )

New interactions between two molecules involved in acute myeloid leukemia (AML) have been found by scientists that may offer a new therapeutic target for cancer treatment.
(Science Daily - News, )

Researchers have discovered that a signaling protein elevated in patients with acute myeloid leukemia (AML) plays a much wider role in the disease than previously thought.
(Science Daily - News, )

Scientists have identified a gene -- FOXC1 -- that, if switched on, causes more aggressive cancer in a fifth of acute myeloid leukemia (AML) patients, according to a study.
(Science Daily - News, )

Laura Handley, 29, from Worcestershire, spotted the same marks James had on Tazmin, 1. Doctors diagnosed acute myeloid leukaemia (AML) a rare cancer which progresses rapidly.
(Daily Mail - Health, )

Novartis' Midostaurin showed promising results in the survival rate of patients diagnosed with AML. Also known as PKC412, the drug will be set for regulatory submissions by 2016.
(Tech Times - Health, )

Three papers now present different aspects of a similar story: altered splicing can lead to myelodysplastic syndrome (MDS) and even to progression to acute myeloid leukaemia (AML).
(Nature Reviews Cancer, )

Familial platelet disorder with predisposition to acute myelogenous leukaemia (FPD/AML) is characterized by abnormal platelet function and a high risk of haematological malignancies.
(Nature Communications, )

In AML cells, CA upregulated SE-associated genes with tumour suppressor and lineage-controlling functions, including the transcription factors CEBPA, IRF8, IRF1 and ETV6 (refs 8).
(Nature, )

The nucleic acid synthesis inhibitor decitabine is a commonly used treatment of patients with myelodysplastic syndromes, and also of elderly patients with acute myeloid leukaemia (AML).
(Nature Reviews Clinical Oncology, )

Although vascular density and vascular endothelial growth factor (VEGF) levels are increased in acute myeloid leukaemia (AML), anti-VEGF therapy has been ineffective in clinical trials.
(Nature Reviews Cancer, )

A new study provides a rationale for the use of poly (ADP-ribose) polymerase (PARP) inhibitors to trigger irreparable DNA damage as a therapeutic approach in acute myeloid leukemia (AML).
(Nature Medicine, )

The new discovery constitutes a major breakthrough in the fight against AML, one of the deadliest forms of leukemia, because it immediately suggests strategies to overcome drug resistance.
(Science Daily - News, )

Here we show that the Mediator-associated kinases cyclin-dependent kinase 8 (CDK8) and CDK19 restrain increased activation of key SE-associated genes in acute myeloid leukaemia (AML) cells.
(Nature, )

Patients with relapsed and/or refractory acute myeloid leukaemia (AML) have a poor prognosis; allogeneic stem-cell transplantation is potentially curative, but many patients are ineligible.
(Nature Reviews Clinical Oncology, )

However, as has been recently discovered, these cells do have a weakness: the enzyme 5-lipoxygenase (5-LO) plays a significant role in the survival of leukaemic AML stem cells, it turns out.
(Science Daily - News, )

Point mutations of the isocitrate dehydrogenases IDH1 and IDH2, found in acute myeloid leukaemia (AML), promote a block in cellular differentiation that is due to global DNA hypermethylation.
(Nature Reviews Drug Discovery, )

The new treatment approach, described in today’s issue of Cancer Cell, was directed against acute myeloid leukemia (AML) cells but may also have potential for attacking other types of cancers.
(Science Daily - News, )

Our results demonstrate that Mediator kinases can negatively regulate SE-associated gene expression in specific cell types, and can be pharmacologically targeted as a therapeutic approach to AML.
(Nature, )

Of the 12 AML patients who received this experimental T-cell therapy after a transplant put their disease in remission, all are still in remission after a median follow-up of more than two years.
(Science Daily - News, )

Researchers have discovered epigenetic changes that contribute to one-fifth of cases of acute myeloid leukemia (AML), an aggressive cancer that arises out of the blood-forming cells in bone marrow.
(Science Daily - News, )

Combining the drug gemtuzumab ozogamicin (GO) with conventional chemotherapy may improve the outcome of bone marrow transplantation for some children battling high-risk acute myeloid leukemia (AML).
(Science Daily - News, )

Leukemia researchers have developed a 17-gene signature derived from leukemia stem cells that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment.
(Science Daily - News, )

The LSC17 score was highly prognostic in five independent cohorts comprising patients of diverse AML subtypes (n = 908) and contributed greatly to accurate prediction of initial therapy resistance.
(Nature, )

Proteasomal degradation of EZH2 in AML patients in response to therapy triggers the expression of stem cell markers and has been identified as an epigenetic pathway leading to acquired drug resistance.
(Nature Medicine, )

Individually increasing or decreasing the expression of these transcription factors suppressed AML cell growth, providing evidence that leukaemia cells are sensitive to the dosage of SE-associated genes.
(Nature, )

A large, new study of adults with acute myeloid leukemia (AML) correlates 80 cancer-related gene mutations with five subtypes of AML, which are defined by the presence of specific chromosomal abnormalities.
(Science Daily - News, )

The high rate of relapse in AML has been attributed to the persistence of leukaemia stem cells (LSCs), which possess a number of stem cell properties, including quiescence, that are linked to therapy resistance.
(Nature, )

At the EORTC–NCI–AACR (ENA) Symposium in Barcelona, promising data for AG-120, an oral inhibitor of the mutated IDH1 gene product, was presented in patients with advanced-stage acute myeloid leukaemia (AML).
(Nature Reviews Clinical Oncology, )

Self-renewing cancer stem cells drive disease in acute myeloid leukaemia (AML) and myelodysplastic syndromes (MDS), but efforts to selectively target these cells have been hampered by a lack of specific markers.
(Nature Reviews Drug Discovery, )

There are several features that distinguish t-AML from de novo AML, including a higher incidence of TP53 mutations, abnormalities of chromosomes 5 or 7, complex cytogenetics and a reduced response to chemotherapy.
(Nature, )

In new research, investigators describe compulsive evolution and dramatic genetic diversity in cells belonging to one of the most treatment-resistant and lethal forms of blood cancer: acute myeloid leukemia (AML).
(Science Daily - News, )

Patients with the most lethal form of acute myeloid leukemia (AML) – based on genetic profiles of their cancers – typically survive for only four to six months after diagnosis, even with aggressive chemotherapy.
(Science Daily - News, )

A moving photographic juxtaposition of a boy named Noah depicting him as an AML patient and later as a survivor is the centrepiece of a new campaign called 'My Life is Proof' promoting the Children’s Cancer Center.
(Daily Mail - Health, )

A new study shows "extremely promising” early phase 1 clinical trial results for the investigational drug AG-120 against the subset of patients with acute myeloid leukemia (AML) harboring mutations in the gene IDH.
(Science Daily - News, )

Cancer researchers have discovered a pre-leukemic stem cell that may be the first step in initiating disease and also the culprit that evades therapy and triggers relapse in patients with acute myeloid leukemia (AML).
(Science Daily - News, )

Here, the authors show that mir-22 functions as a tumour suppressor in de novo acute myeloid leukaemia by inhibiting the expression of several oncogenes and that restoring mir-22 expression suppresses AML progression.
(Nature Communications, )

Here the authors show that these cells have elevated GSK3β, and that its inhibition prolongs survival of mice transplanted with human AML and stimulates NK cytotoxicity via increased adhesion of NK cells to their targets.
(Nature Communications, )

The chemotherapy treatments necessary to treat Acute Myeloid Leukemia (AML) in children can be grueling on the body, and can cause health-related complications during therapy, as well as long down the road after remission.
(Science Daily - News, )

AML with high levels of BCAT1 (BCAT1high) displayed a DNA hypermethylation phenotype similar to cases carrying a mutant isocitrate dehydrogenase (IDHmut), in which TET2 is inhibited by the oncometabolite 2-hydroxyglutarate.
(Nature, )

The LSC17 score provides clinicians with a rapid and powerful tool to identify AML patients who do not benefit from standard therapy and who should be enrolled in trials evaluating novel upfront or post-remission strategies.
(Nature, )

AML is a devastating disease and proves fatal within five years for 90 per cent of seniors over age 65. This new avocado-derived drug could one day significantly increase life expectancy and quality of life for AML patients.
(Science Daily - News, )

A new study provides the first insights into epigenetic heterogeneity in AML. The study highlights a striking independence of genetic and epigenetic variation, and links the kinetics of epigenetic change to clinical outcome.
(Nature Medicine, )

A number of highly recurrent mutations associated with acute myeloid leukaemia (AML) have been identified using genomic approaches, but a link between mutations detected at diagnosis and disease outcome has so far not been found.
(Nature Reviews Clinical Oncology, )

Following the discovery of BRD4 as a non-oncogene addiction target in acute myeloid leukaemia (AML), bromodomain and extra terminal protein (BET) inhibitors are being explored as a promising therapeutic avenue in numerous cancers.
(Nature, )

Here, the authors demonstrate that the cell of origin determines the aggressiveness of AML in a mouse model and identify unique biomarkers of the specific leukaemia cell of origin by profiling open chromatin regions of AML samples.
(Nature Communications, )

Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers.
(Science Daily - News, )

Other examples

See also examples for amls.

Don't miss the pronunciation examples of AML to learn how to say it correctly!

Share this page

Next...

Go to the thesaurus of AML to find many related words and phrases!


Privacy Policy | Cookies Policy
Keyword Tool | Romanian-English Dictionary