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Header of Acute Kidney Injury

Examples of Acute Kidney Injury

Sentences

69 examples:

Acute kidney injury (AKI) affects 3% of all hospitalized patients.
(Nature, )

Acute kidney injury (AKI) is a widespread problem of epidemic status.
(Nature Reviews Nephrology, )

Acute kidney injury can be a serious complication following heart surgery.
(Science Daily - News, )

Acute kidney injury (AKI) is a major health problem in China say researchers.
(Nature Reviews Nephrology, )

Nephrotoxin-induced acute kidney injury (AKI) is a considerable risk among hospitalized children.
(Nature Reviews Nephrology, )

Acute kidney injury (AKI) prolongs hospital stay and increases mortality in various clinical settings.
(Nature Reviews Nephrology, )

Acute kidney injury’s harmful effects on heart health were comparable to those attributed to diabetes.
(Science Daily - News, )

Fluid therapy with saline is considered by some to confer a notable risk of acute kidney injury and mortality.
(Nature Reviews Nephrology, )

Ultrasound treatments may prevent acute kidney injury that commonly arises after major surgery, according to a new study.
(Science Daily - News, )

Automated, real-time alert systems have the potential to improve recognition and management of acute kidney injury (AKI).
(Nature Reviews Nephrology, )

Early diagnosis of acute kidney injury in preterm infants is possible through urinary protein markers, say investigators.
(Science Daily - News, )

A report commissioned by the NHS found that acute kidney injury (AKI) causes between 15,000 and 40,000 excess deaths every year.
(Daily Mail - News, )

Phospholipase A2 (PLA2) ameliorates cisplatin-induced acute kidney injury by modulating inflammatory responses, say researchers.
(Nature Reviews Nephrology, )

In 2014, key articles in the field of acute kidney injury highlighted the importance of tubular homeostasis in renal regeneration.
(Nature Reviews Nephrology, )

A recent trial does not support the use of high-dose atorvastatin for prevention of acute kidney injury (AKI) after cardiac surgery.
(Nature Reviews Nephrology, )

A KIM-1–AIM interaction promotes clearance of cellular debris in renal tubules after acute kidney injury to improve disease outcome.
(Nature Medicine, )

This technology has the potential to revolutionize the treatment of infants with acute kidney injury, according to new research published.
(Science Daily - News, )

Inhibitors of the cyclin-dependent kinase (CDK) 4/6 pathway could protect against drug-induced acute kidney injury (AKI), say researchers.
(Nature Reviews Nephrology, )

Clinical trials in patients with acute kidney injury (AKI) have been stymied by a lack of consensus on suitable renal-specific end points.
(Nature Reviews Nephrology, )

Researchers have postulated that scattered tubular cells (STCs) might be the origin of regenerating tubular cells after acute kidney injury.
(Nature Reviews Nephrology, )

Acute kidney injury is an increasingly common complication of hospital admission and is associated with high levels of morbidity and mortality.
(Nature Reviews Nephrology, )

A single low dose of lithium given to mice following acute kidney injury promotes kidney repair and accelerates the recovery of kidney function.
(Science Daily - News, )

Renal progenitor cells derived from human iPS cells were shown to have therapeutic effects when transplanted into acute kidney injury model mice.
(Science Daily - News, )

New research shows clear association between ACE inhibitors -- drugs used to treat high blood pressure and heart disease -- and acute kidney injury.
(Science Daily - News, )

Cardiac surgery often requires the use of cardiopulmonary bypass, which can cause an inflammatory cascade that results in acute kidney injury (AKI).
(Nature Reviews Nephrology, )

Mitochondrial dysfunction contributes to the pathophysiology of tissue injury in acute kidney injury (AKI), but the mechanisms involved are unclear.
(Nature Reviews Nephrology, )

Acute kidney injury occurs frequently in Ebola virus disease; however, providing hemodialysis to these patients was previously thought to be too risky.
(Science Daily - News, )

The mechanisms underlying acute kidney injury (AKI) progression are incompletely understood, and there are currently no effective treatments available.
(Nature Reviews Drug Discovery, )

Among 3,585 consecutive patients in two tertiary hospitals, 31.5% had CKD before cardiac surgery and 27.6% developed postoperative acute kidney injury (AKI).
(Nature Reviews Nephrology, )

A class of drugs sometimes used to control symptoms of dementia appears to increase the risk of acute kidney injury in people who take it, a new study suggests.
(The Vancouver Sun - Health, )

Experts say acute kidney injury is one of the biggest challenges facing the NHS today with the condition claiming the lives of more than 1,000 patients a month.
(Daily Mail - News, )

In pregnancies affected by severe acute kidney injury, babies are at increased risk of having low birth weights or being born prematurely, the researchers report.
(Science Daily - News, )

Findings from a retrospective cohort study show that acute kidney injury (AKI) is an independent risk factor for subsequent development of elevated blood pressure.
(Nature Reviews Nephrology, )

Lupus nephritis is a common and severe manifestation of systemic lupus erythematosus, and an important cause of both acute kidney injury and end-stage renal disease.
(Nature Reviews Nephrology, )

A prospective, double-blind, randomized trial has assessed whether infusion of sodium bicarbonate is protective against contrast-induced acute kidney injury (CI-AKI).
(Nature Reviews Nephrology, )

The 0by25 Global Snapshot sheds light on the recognition, management and outcomes of acute kidney injury (AKI) in countries worldwide stratified by gross national income.
(Nature Reviews Nephrology, )

A class of drugs sometimes used to control symptoms of dementia appears to increase the risk of acute kidney injury in people who take it, a new study in Ontario suggests.
(The Canadian Press in CBC News - Health, )

Acute kidney injury (AKI) is a common complication in hospitalized patients, associated with >50% mortality in those in intensive care who require renal replacement therapy.
(Nature Reviews Nephrology, )

Despite uncertainty in the KDIGO guidelines, new research has shown that they can accurately identify acute kidney injury in critically ill patients who have a high risk of mortality.
(Nature Reviews Nephrology, )

Establishing a programme for the prevention and treatment of acute kidney injury, chronic kidney disease and end-stage renal disease in a developing country involves unique challenges.
(Nature Reviews Nephrology, )

Acute kidney injury (AKI) associated with tenofovir disoproxil fumarate (TDF) was prevalent among HIV-infected patients and demonstrated a high morbidity rate in a new center-based study.
(Science Daily - News, )

The renin–angiotensin system (RAS) has been implicated in the pathogenesis of acute kidney injury (AKI), but conflicting outcomes have been reported in patients following RAS inhibition.
(Nature Reviews Nephrology, )

Levels of FGF-23 increase early in the course of acute kidney injury (AKI) following cardiac surgery and are independently associated with severe AKI and adverse outcomes, say researchers.
(Nature Reviews Nephrology, )

Insufficient repair of proximal tubular epithelium (PTE) cells following acute kidney injury (AKI) can result in inflammatory and fibrotic responses, which may progress to chronic renal failure.
(Nature Reviews Drug Discovery, )

A biomarker test developed initially to identify early acute kidney injury after surgery has been shown to successfully detect it in emergency room patients with a variety of urgent health issues.
(Science Daily - News, )

Hospitalized patients who recovered from acute kidney injury had a 67% increased risk of experiencing coronary events or dying during a recent study, suggesting that there is a linkage between the two.
(Science Daily - News, )

Patients with chronic kidney disease (CKD) are more susceptible to acute kidney injury (AKI) than are patients without CKD, but the mechanisms contributing to this increased susceptibility are unclear.
(Nature Reviews Nephrology, )

Cell death is an important pathological feature of acute kidney injury (AKI), with debris from dead tubular epithelial cells (TECs) leading to renal tubular obstruction and exacerbating tubular injury.
(Nature Reviews Nephrology, )

Uncertainty exists regarding the optimal timing of initiation of renal replacement therapy in critically ill patients with acute kidney injury in the absence of urgent or life-threatening complications.
(Nature Reviews Nephrology, )

Urinary angiotensinogen levels at the time of hospital admission predicted acute decompensated heart failure patients' risk of developing acute kidney injury with considerable accuracy, scientists report.
(Science Daily - News, )

High levels of two novel urinary biomarkers early in critical illness are associated with adverse long-term outcomes in patients with acute kidney injury (AKI), according to an international, multi-center study.
(Science Daily - News, )

The incidence of acute kidney injury that requires dialysis is 1 in 10,000 pregnancies, a new Canadian study reports; otherwise healthy women who acquire a major pregnancy-related complication are at increased risk.
(Science Daily - News, )

The development of effective therapeutics based on RNA interference (RNAi) to prevent or treat acute kidney injury (AKI) has been hindered due to confounds such as poor tissue-specific delivery and off-target effects.
(Nature Reviews Nephrology, )

Expression of kidney injury molecule 1 (KIM-1) correlates with damage to the proximal tubule in acute kidney injury and chronic kidney disease (CKD), but little is known about the role of this protein in kidney injury.
(Nature Reviews Nephrology, )

They show that a personalized hydration strategy—guided by intracardiac pressure—significantly decreases the rate of contrast-induced acute kidney injury (AKI) compared with a standard fluid administration protocol.
(Nature Reviews Nephrology, )

Atypical haemolytic uraemic syndrome (aHUS), an important cause of acute kidney injury, is characterized by dysregulation of the complement pathway, frequent need for dialysis, and progression to end-stage renal disease.
(Nature Reviews Nephrology, )

New research has demonstrated that use of the off-pump coronary artery bypass graft (CABG) technique in cardiac surgery reduces the occurrence of postoperative acute kidney injury (AKI) compared with on-pump CABG surgery.
(Nature Reviews Nephrology, )

FDA approval of the first device to use novel biomarkers of kidney damage to assess risk of acute kidney injury (AKI) potentially brings forward diagnosis of moderate-to-severe AKI to a time frame that could enable early intervention.
(Nature Reviews Nephrology, )

Taking the antibiotic clarithromycin with certain statins could increase risk of acute kidney injury and other serious adverse effects among older adults, according to a new study published in the Canadian Medical Association Journal.
(Trinh Theresa Do in CBC News - Health, )

Recent studies have reported that monitoring urinary concentrations of TIMP-2 and IGFBP7 using the NephroCheck® test (Astute Medical, USA), might serve as an early method to detect acute kidney injury (AKI) following cardiac surgery.
(Nature Reviews Nephrology, )

A randomized multicentre controlled study of 240 cardiac surgery patients at high risk of acute kidney injury (AKI) has demonstrated that remote ischaemic preconditioning can reduce the rate of AKI and requirement for renal replacement therapy.
(Nature Reviews Nephrology, )

The past decade has seen developments in several aspects of acute kidney injury (AKI), including the discovery of an array of biomarkers, assessment of the optimal dose intensity for renal replacement therapy, and the impact of fluid administration.
(Nature Reviews Nephrology, )

Both acute kidney injury and chronic kidney disease were common in patients undergoing major vascular surgical procedures and were associated with an increase in long-term cardiovascular-specific death compared with patients with no kidney disease, according to a study.
(Science Daily - News, )

The dopamine D1 receptor agonist fenoldopam mesylate does not prevent deterioration of renal function in patients with early acute kidney injury (AKI) after cardiac surgery, according to new findings from a randomized controlled trial (RCT) by Tiziana Bove and colleagues.
(Nature Reviews Nephrology, )

Genetic or autoimmune defects that lead to dysregulation of the alternative pathway of complement have been associated with the development of atypical haemolytic uraemic syndrome (aHUS), which is characterized by thrombocytopenia, haemolytic anaemia and acute kidney injury.
(Nature Reviews Nephrology, )

Among older adults taking a calcium-channel blocker, simultaneous use of the antibiotic clarithromycin, compared with azithromycin, was associated with a small but statistically significant greater 30-day risk of hospitalization with acute kidney injury, according to a study.
(Science Daily - News, )

Pharmacologic antagonism of the mineralocorticoid receptor is effective in preventing acute kidney injury (AKI) after ischaemia/reperfusion (I/R), but the underlying mechanisms and the renal cell types targeted by mineralocorticoid receptor antagonists (MRAs) were previously unknown.
(Nature Reviews Nephrology, )

Sirtuin 3 (SIRT3) protects against acute kidney injury (AKI) by preserving mitochondrial integrity and could be a target for improving outcomes of patients with AKI, say researchers. “Pharmacological manipulations that increase SIRT3 improve renal function and decrease tubular injury in mice,” explains researcher Ariela Benigni.
(Nature Reviews Nephrology, )

In four years of follow up of 1464 participants in the randomized controlled trial Randomised Evaluation of Normal vs. Augmented Levels of RRT (RENAL) study, medical researchers found that patients with acute kidney injury in an intensive care unit who require renal replacement therapy (RRT; hemodialysis combined with hemofiltration) do not benefit from higher intensity RRT.
(Science Daily - News, )

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