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Examples of Adhesions

Sentences with the noun Adhesions

2 examples:

The mechanical regulation of cadherin adhesions is now shown to involve myosin-dependent tension in the cortical actomyosin cytoskeleton.
(Nature Cell Biology, )

The growth and collapse of focal adhesions are mirrored by, respectively, the nuclear or cytosolic localization of the transcriptional regulator protein YAP.
(Nature, )

Other sentences

34 examples:

Cells stick to one another through physical contacts called cell adhesions.
(Science Daily - News, )

At cell–cell adhesions, α-catenin contains a cryptic vinculin-binding site.
(Nature Communications, )

Vinculin (VCL) accumulates at both types of adhesions, where it may exert distinct functions.
(Nature Reviews Molecular Cell Biology, )

Epithelial cells form energetically costly cell–cell adhesions in response to mechanical forces.
(Nature Cell Biology, )

Regulated assembly and disassembly of cell–matrix adhesions is critical for efficient cell migration.
(Nature Reviews Molecular Cell Biology, )

Sun et al. now identify Kank2 as an activator of talin that reduces force transmission across focal adhesions.
(Nature Cell Biology, )

Wittmann and colleagues demonstrate that the turnover of mature focal adhesions is regulated by CLASP proteins.
(Nature Cell Biology, )

Bertocchi and colleagues describe the organization of cadherin-based adhesions using super-resolution microscopy.
(Nature Cell Biology, )

Rachael Harley, 19, from Balmedie, near Aberdeen, has abdominal adhesions - fibrous bands of tissue between her organs.
(Daily Mail - News, )

Researchers have comprehensively described the network of proteins involved in cell-cell adhesions, or the cadherin interactome.
(Science Daily - News, )

Langhe et al. show that cadherin-11 mediates adhesion to the cell matrix at focal adhesions through interaction with syndecan-4.
(Nature Communications, )

Integrin-based focal adhesions integrate biochemical and biomechanical signals from the extracellular matrix and the actin cytoskeleton.
(Nature Cell Biology, )

Researchers have developed a new form of microscopy that allows them to observe the formation and evolution of cell membrane focal adhesions.
(Science Daily - News, )

Cells sense external mechanical forces through cadherins (which form cell–cell adhesions) and integrins (which form cell–matrix adhesions).
(Nature Reviews Molecular Cell Biology, )

Researchers show the transcription factor p73 promotes this process by regulating the adhesions between developing sperm and their support cells.
(Science Daily - News, )

Labernadie et al. now show that heterotypic adhesions between E-cadherin on cancer cells and N-cadherin on CAFs transmit forces to drive invasion.
(Nature Cell Biology, )

The spectraplakin protein ACF7 binds to actin at focal adhesions and targets microtubule plus ends to focal adhesions, promoting their disassembly.
(Nature Communications, )

Single-cell mechanical homeostasis is found to be driven by the mechanosensitive, collective subcellular dynamics of cytoskeletal tension and focal adhesions.
(Nature Materials, )

Cell-matrix adhesions may increase or decrease in size in response to tension; however, the factors determining which of these responses predominates remain unclear.
(Nature Communications, )

It has previously been shown that disassembly of these adhesions depends mostly on integrin endocytosis, but the fate of internalized integrins has remained elusive.
(Nature Reviews Molecular Cell Biology, )

Focal adhesions are integrin-based complexes through which cells interact with the extracellular matrix, and their regulated assembly and disassembly underlies cell migration.
(Nature Reviews Molecular Cell Biology, )

We find that increasing the spacing between ligands promotes the growth of focal adhesions on low-rigidity substrates, but leads to adhesion collapse on more-rigid substrates.
(Nature, )

An analytical method, with accompanying software, is described for improved fidelity in traction force microscopy and is used to measure forces at emerging focal adhesions at high resolution.
(Nature Methods, )

Loss of podocyte adhesion is a major contributing factor to the progression of glomerular disease; however, comprehensive understanding of the role of focal adhesions (FAs) in podocyte biology is lacking.
(Nature Reviews Nephrology, )

At tissue boundaries, cellular repulsive events are manifested as deformation waves that result from an oscillatory pattern of traction forces and intracellular stress that pull cellular adhesions away from the boundary.
(Nature Materials, )

The combination of three-dimensional super-resolution imaging and loss- or gain-of-function protein mutants now links the nanoscale dynamic localization of proteins to their activation and function within focal adhesions.
(Nature Cell Biology, )

Our results provide a general framework for how cells sense spatial and physical information at the nanoscale, precisely tuning the range of conditions at which they form adhesions and activate transcriptional regulation.
(Nature, )

They show that CLASP recruitment to focal adhesions is involved in localized exocytosis and extracellular matrix degradation, suggesting that local matrix metalloprotease secretion might promote focal adhesion disassembly.
(Nature Cell Biology, )

Here, Chorev et al. identify a novel ‘hybrid complex’ consisting of the actin-nucleating three-subunit core of Arp2/3 and the focal adhesion adapter, vinculin, that localizes to, and modulates the growth of, focal adhesions.
(Nature Communications, )

Apart from serving as physical connections that enable cells to form tissues, cell adhesions also allow the cells to sense, signal, and respond to physical or chemical changes in the environment, as well as interact with neighboring cells.
(Science Daily - News, )

Case and Waterman discuss how integrating extracellular-matrix-bound integrins and the actin cytoskeleton into a mechanosensitive molecular clutch transmits actin-cytoskeleton-generated forces to the extracellular matrix through focal adhesions.
(Nature Cell Biology, )

Waterman and colleagues use super-resolution microscopy and biosensor technology to characterize the spatiotemporal regulation of the protein interactions within focal adhesions that control vinculin activation and function during focal adhesion maturation.
(Nature Cell Biology, )

Now, a combination of experiments and mathematical modelling has been used to describe the precise molecular and physical mechanism by which cells sense and respond to the mechanical properties of their extracellular environment through integrin-based adhesions.
(Nature Cell Biology, )

Previous studies of cells on rigid glass surfaces have shown that spatial sensing of ECM ligands takes place at the nanometre scale, with integrin clustering and subsequent formation of focal adhesions impaired when single integrin–ligand bonds are separated by more than a few tens of nanometres.
(Nature, )

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