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Header of Agonism

Examples of Agonism


5 examples:

Restriction of FXR agonism to the gut improves obesity and diabetes.
(Nature Medicine, )

We conclude that PrPC promotes myelin homeostasis through flexible tail-mediated Gpr126 agonism.
(Nature, )

However, the partial agonism exhibited by RGD ligand–based drugs can result in life-threatening complications.
(Nature Structural & Molecular Biology, )

Thus, partial agonism is achieved here by conformational selection of a distinct active state which we predict will have compromised coupling to the G protein.
(Nature, )

A combination therapy of opioid receptor agonism plus peripheral-restricted MOR antagonism abrogates these side-effects while preserving opioid analgesia in rodent models of peri-operative and chronic pain.
(Nature Medicine, )

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