Examples of Agonism
Restriction of FXR agonism to the gut improves obesity and diabetes.
(Nature Medicine, )
We conclude that PrPC promotes myelin homeostasis through flexible tail-mediated Gpr126 agonism.
However, the partial agonism exhibited by RGD ligand–based drugs can result in life-threatening complications.
(Nature Structural & Molecular Biology, )
Thus, partial agonism is achieved here by conformational selection of a distinct active state which we predict will have compromised coupling to the G protein.
Share this page
Go to the wordplay of Agonism for some fun with words!