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Examples of Aire

Sentence with the noun Aire

1 example:

Abramson and colleagues show that Sirt1 has high expression in the thymus, where it deacetylates the transcriptional regulator Aire and is essential for Aire's ability to switch on the expression of tissue-specific genes.
(Nature Immunology, )

Other sentences

16 examples:

Come it aire, come it late, in May comes the Cow-quake.
(Scotch proverb)

Ji'Aire Lee was found on a swing at Wills Memorial Park on the morning of May 22.
(USA Today - National, )

Nigerian-born Chris Aire is a famous jeweler whose A-list clients include movie and music stars.
(CNN - World Business, )

Anderson and colleagues show that Aire achieves such targeting by coopting the ATF7ip-MBD1 repressor complex.
(Nature Immunology, )

Autoimmune regulator (AIRE) promotes the perinatal development of a distinct population of regulatory T cells.
(Nature Reviews Immunology, )

Meet Nigerian-born Chris Aire, the 'King of Bling' and preferred jeweler to the upper echelons of the Hollywood elite.
(Forbes - Entrepreneurs, )

The transcriptional regulator Aire is required for central tolerance, but how it manages to target tissue-specific genes is unclear.
(Nature Immunology, )

Un technicien de la Force opérationnelle aérienne en Irak (FOA I) guide le pilote d’un chasseur CF188 Hornet sur l’aire de trafic
(The Canadian Press in CBC News - Politics, )

More than 15 years ago, mutations in the autoimmune regulator (AIRE) gene were identified as the cause of autoimmune polyglandular syndrome type 1 (APS1).
(Nature Reviews Immunology, )

Pierre Coulombe and colleagues show that the autoimmune regulator Aire is induced in tumor keratinocytes in a keratin 17 (K17)-dependent manner and promotes skin tumorigenesis in mice.
(Nature Genetics, )

Here the authors show that Jmjd6 directs splicing of a central tolerance regulator Aire in medullary thymic epithelial cells, and that Jmjd6 deficiency leads to loss of Aire and multi-organ autoimmunity in mice.
(Nature Communications, )

Here the authors develop a new model of skin autoimmunity and show that the size of tissue-specific Treg pool in the thymus depends on AIRE, the availability of the tissue antigen, and its presentation by dendritic cells.
(Nature Communications, )

Here the authors show that androgen receptor upregulates Aire and Aire-dependent transcription in the thymic epithelium, and that Aire is required for androgen-mediated suppression of experimental autoimmune encephalitis.
(Nature Communications, )

They further show that K17 and Aire colocalize in the nucleus and bind a subset of proinflammatory genes, providing a molecular explanation for the K17-dependent amplification of inflammatory responses in diseased epithelia.
(Nature Genetics, )

A new study shows that patients deficient in autoimmune regulator (AIRE) have high-affinity neutralizing antibodies against type 1 interferons (IFNs), levels of which inversely correlate with type 1 diabetes mellitus (T1DM).
(Nature Reviews Endocrinology, )

Sirtuin-1 (Sirt1), a protein deacetylase known for its multiple cellular functions, including roles in metabolism, stress response and aging, is a post-translational modulator of autoimmune regulator (Aire) in central immunotolerance.
(Nature Immunology, )

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See also examples for aires, aired, airing.

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