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Examples of Allogeneic


22 examples:

The study enrolled 148 caregivers of allogeneic hematopoietic stem cell (Allo-HSCT) patients.
(Science Daily - News, )

The purpose of this study was to evaluate the effects of ibandronate on bone loss following allogeneic stem cell transplantation (allo-SCT).
(BoneKEy Reports, )

These results reveal that tumour-binding allogeneic IgG can induce powerful antitumour immunity that can be exploited for cancer immunotherapy.
(Nature, )

Bone-marrow-derived progenitor cells contribute to adipogenesis in patients who have undergone allogeneic transplantation, according to a new study.
(Nature Reviews Endocrinology, )

Graft-versus-host disease (GVHD) represents the most serious and challenging complication of allogeneic haematopoietic stem-cell transplantation (HSCT).
(Nature Reviews Clinical Oncology, )

Amniotic membrane allografts from donated human placentae, which are a source of allogeneic extracellular matrix (ECM), can have anti-inflammatory effects.
(Nature Reviews Rheumatology, )

Although embryonic stem cells (ES cells) from in vitro fertilized embryos (IVF ES cells) represent the ‘gold standard’, they are allogeneic to patients.
(Nature, )

Prior to the development of targeted therapies and in the absence of allogeneic haematopoetic stem-cell transplantation (HSCT), the median survival was 57 years.
(Nature Reviews Clinical Oncology, )

Allogeneic blood or bone-marrow transplantation (alloBMT) is a potentially curative treatment for a variety of haematological malignancies and nonmalignant diseases.
(Nature Reviews Clinical Oncology, )

Here we describe an allogeneic transplantation model established using the cynomolgus monkey (Macaca fascicularis), the MHC structure of which is identical to that of humans.
(Nature, )

Although major histocompatibility complex (MHC)-matched allogeneic transplantation is a promising alternative strategy, few immunological studies have been carried out with iPSCs.
(Nature, )

Patients with relapsed and/or refractory acute myeloid leukaemia (AML) have a poor prognosis; allogeneic stem-cell transplantation is potentially curative, but many patients are ineligible.
(Nature Reviews Clinical Oncology, )

Collectively, our data demonstrate that allogeneic iPSC-CM transplantation is sufficient to regenerate the infarcted non-human primate heart; however, further research to control post-transplant arrhythmias is necessary.
(Nature, )

Treatment with IL-22 in vivo after mouse allogeneic bone marrow transplantation enhanced the recovery of ISCs, increased epithelial regeneration and reduced intestinal pathology and mortality from graft-versus-host disease.
(Nature, )

A multicenter phase 1 trial of the immune checkpoint blocker ipilimumab found clinical benefit in nearly half of blood cancer patients who had relapsed following allogeneic stem cell transplantation, according to investigators.
(Science Daily - News, )

Allogeneic stem-cell transplantation (allo-SCT) is the last potentially curative treatment option for patients with relapsed haematological cancer, although many subsequently develop progressive disease and have a dismal prognosis.
(Nature Reviews Clinical Oncology, )

Here we find that allogeneic tumour rejection is initiated in mice by naturally occurring tumour-binding IgG antibodies, which enable dendritic cells (DCs) to internalize tumour antigens and subsequently activate tumour-reactive T cells.
(Nature, )

In this model, the middle cerebral artery (MCA) is occluded with a fibrin-rich allogeneic clot, producing an embolic model of MCA occlusion in the rat that mimics the key components of neurovascular damage observed in human ischemic stroke.
(Nature Protocols, )

Much like transplanted allogeneic organs, allogeneic tumours are reliably rejected by host T cells, even when the tumour and host share the same major histocompatibility complex alleles, the most potent determinants of transplant rejection.
(Nature, )

Robert Zeiser and colleagues now report that neutrophils also contribute to the severity of graft-versus-host disease following translocation of bacteria in the gut induced by the conditioning regimen for allogeneic hematopoietic cell transplantation.
(Nature Medicine, )

After allogeneic haematopoietic stem-cell transplantation (alloHSCT), many patients with progressive B-cell malignancies receive unmanipulated donor lymphocyte infusions; however, responses are often poor and graft-versus-host disease (GvHD) is common.
(Nature Reviews Clinical Oncology, )

Either systemic administration of DCs loaded with allogeneic-IgG-coated tumour cells or intratumoral injection of allogeneic IgG in combination with DC stimuli induced potent T-cell-mediated antitumour immune responses, resulting in tumour eradication in mouse models of melanoma, pancreas, lung and breast cancer.
(Nature, )

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