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Header of Antifibrotic

Examples of Antifibrotic


6 examples:

Activation of type 1 angiotensin (AT1) receptors on infiltrating macrophages might have antifibrotic effects.
(Nature Reviews Nephrology, )

Riociguat, a soluble guanylate cyclase stimulator under development by Bayer, is thought to have vasodilating, antiproliferative and antifibrotic effects.
(Forbes - Technology, )

Indeed, as the prevalence of end-stage renal disease is constantly on the rise, the lack of established antifibrotic therapies is a considerable unmet need in clinical practice.
(Nature Reviews Nephrology, )

An inhibitor of Aurora kinase promotes megakaryocytic differentiation of cells from patients with primary myelofibrosis and shows antifibrotic effects in mouse models of this disease.
(Nature Medicine, )

β is a key mediator of fibrosis, and understanding the mechanisms by which this cytokine exerts its profibrotic effects is important for the identification of new antifibrotic targets.
(Nature Reviews Nephrology, )

New research published in Annals of the Rheumatic Diseases suggests inhibition of phosphodiesterase 4 (PDE4) could have disease-modifying antifibrotic effects in systemic sclerosis (SSc), particularly in those patients with inflammation-driven fibrosis.
(Nature Reviews Rheumatology, )

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