Examples of Auton
Comedian Rob Auton, from York, wins an award for the funniest joke of the Edinburgh Fringe, voted for by the public.
(BBC News - Entertainment & Arts, )
For nucleosomes with short linker DNA, Acf1 preferentially binds to the H4 tail, allowing AutoN to inhibit the ATPase activity of Snf2h.
Little-known stand-up comedian Rob Auton (pictured) told the funniest joke of this year’s Edinburgh Fringe Festival, according to a public poll.
(Daily Mail - News, )
Mutation of AutoN, an auto-inhibitory domain within Snf2h that bears sequence homology to the H4 tail, abolishes the linker-length sensitivity in remodelling.
As the linker DNA lengthens, Acf1 shifts its binding preference to the linker DNA, freeing the H4 tail to compete AutoN off the ATPase and thereby activating ACF.
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