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Examples of Ablation

Sentences with the noun Ablation

4 examples:

When studying neural circuitry, the ablation of synapses may be an alternative to optogenetic manipulation of neurons.
(Nature Methods, )

We also demonstrate that an ablation of dentate gyrus engram cells containing restored spine density prevents the rescue of long-term memory.
(Nature, )

In October 2015, the U.S. Food and Drug Administration (FDA) approved the first ultrasound system for the ablation of prostate tissue in the United States.
(Fox News - Health, )

From the ablation of small, unresectable tumours to experimental therapies, percutaneous radiofrequency ablation, microwave ablation, cryoablation and irreversible electroporation have an increasing role in the treatment of solid neoplasms.
(Nature Reviews Cancer, )

Other sentences

94 examples:

Easing heart palpitations is one benefit of catheter ablation.
(Science Daily - News, )

Laser ablation therapy (LAT) is an outpatient procedure used to treat thyroid nodules.
(Nature Reviews Endocrinology, )

Study shows 60 drop in cardiovascular mortality after ablation for atrial fibrillation.
(Science Daily - News, )

Inhibition or genetic ablation of COX-2 activity impairs fracture healing in animal models.
(BoneKEy Reports, )

Ablation of PVT1 from MYC-driven colon cancer line HCT116 diminished its tumorigenic potency.
(Nature, )

Minimally invasive thermal ablation of tumours has become common since the advent of modern imaging.
(Nature Reviews Cancer, )

Thus, conditional ablation of Atg5 or Atg7 in intestinal APCs resulted in enhanced ROS and TH17 responses.
(Nature, )

In contrast, inhibition or genetic ablation of 5-LO activity accelerates fracture healing in animal models.
(BoneKEy Reports, )

Neurosurgeons have found MRI-guided laser ablation to be an effective therapy for certain epilepsy patients.
(Science Daily - News, )

Moreover, genetic ablation of AAVR renders a wide range of mammalian cell types highly resistant to AAV2 infection.
(Nature, )

Ablation of the cellular prion protein PrPC leads to a chronic demyelinating polyneuropathy affecting Schwann cells.
(Nature, )

Upon selective pharmacological or genetic ablation of nociceptors, DDCs failed to produce IL-23 in imiquimod-exposed skin.
(Nature, )

Experts have recommended uninterrupted anticoagulation with vitamin K antagonists during ablation and device implantation.
(Science Daily - News, )

The complexity of the laser design arises from the need to overcome the high pulse energy threshold for efficient ablation.
(Nature, )

Epithelial FADD ablation inhibited IEC apoptosis and prevented the premature death of mice with IEC-specific RIPK1 knockout.
(Nature, )

Genetic ablation of EF4 in mice is now found to cause testis-specific mitochondrial deficiency and impaired spermatogenesis.
(Nature Structural & Molecular Biology, )

Progression to CRPC after androgen ablation therapy is predominantly driven by deregulated androgen receptor (AR) signalling.
(Nature, )

Data from a prospective, European registry of patients undergoing catheter ablation of atrial fibrillation have now been published.
(Nature Reviews Cardiology, )

Here we circumvent this limitation by exploiting ablation cooling, in analogy to a technique routinely used in aerospace engineering.
(Nature, )

Consistent with their obligatory role in regulating appetite, genetic ablation or chemogenetic inhibition of AgRP neurons decreases feeding.
(Nature, )

MYC ablation impairs glycolysis, mitochondrial function and proliferation of ECs while its EC-specific overexpression fuels these processes.
(Nature, )

Thermal ablation with magnetic resonance-guided focused ultrasound surgery (MRgFUS) is a noninvasive technique for treating fibroids and cancer.
(Science Daily - News, )

A 'triple attack' technique combining chemotherapy, thermal ablation, and hyperthermia provided a highly targeted, yet minimally invasive approach.
(Science Daily - News, )

In addition, radiofrequency catheter ablation for AF that is nonresponsive to antiarrhythmic drug therapy is becoming an ever more common procedure.
(Nature Reviews Cardiology, )

Here, the authors show that SHP-1 ablation impairs the establishment of long-lived bone marrow-resident plasma cells due to aberrant integrin activation.
(Nature Communications, )

This elevated Sm/Nd has been ascribed either to a ‘hidden’ reservoir in the Earth or to loss of an early-formed terrestrial crust by impact ablation.
(Nature, )

We also show that the selective ablation of DASCp63/Krt5in vivo prevents this regeneration, leading to pre-fibrotic lesions and deficient oxygen exchange.
(Nature, )

Ablation of the tumor suppressor phosophatase and tensin homlog (PTEN) unexpectedly suppresses the development of pre-B acute lymphoblastic leukemia (ALL).
(Nature Medicine, )

Here, the authors show a cold ablation process that takes off below both the threshold for plasma formation and that of the melting point of alkali halides.
(Nature Communications, )

Here, the authors show that Snf2h ablation impairs chromatin organization of neuronal lineages during mouse embryonic and post-natal cerebellar development.
(Nature Communications, )

Genetic ablation of COX-1 does not affect the fracture callus strength in mice, suggesting that COX-2 activity is primarily responsible for regulating fracture healing.
(BoneKEy Reports, )

Radiofrequency catheter ablation (RFA) might be more effective than antiarrhythmic drug (AAD) therapy as a first-line treatment for paroxysmal atrial fibrillation (AF).
(Nature Reviews Cardiology, )

Furthermore, targeted ablation of a sparse population of cortico-fugal neurons that specifically project to the accessory optic system severely impairs OKR potentiation.
(Nature, )

Catheter-guided mapping and electrical ablation are commonly used to treat cardiac arrhythmias, and these techniques may soon be available to treat patients with epilepsy.
(Nature Reviews Neurology, )

The use of femtosecond laser pulses allows precise and thermal-damage-free removal of material (ablation) with wide-ranging scientific, medical and industrial applications.
(Nature, )

Here, the authors show that genetic ablation of Ripk3 results in adipocyte apoptosis and white adipose tissue inflammation in obese mice, which promotes glucose intolerance.
(Nature Communications, )

Through cellular and genetic ablation we show that epithelial cell death is extrinsically induced through transforming growth factor (TGF)-β activation and mesenchymal crosstalk.
(Nature, )

Intracoronary imaging and sensing, laser ablation and optical pacing are just some of the functions being explored to help diagnose and treat conditions of the heart and arteries.
(Nature Photonics, )

Furthermore, optogenetic activation or increased TH expression in the AVPV TH+ neurons of female mice increases circulating oxytocin, whereas their ablation reduces oxytocin levels.
(Nature, )

Image-guided ablation (IGA) techniques have evolved considerably over the past 20 years and are increasingly used to definitively treat small primary cancers of the liver and kidney.
(Nature Reviews Clinical Oncology, )

The primary analysis of FIRE AND ICE demonstrated that cryoablation was noninferior to radiofrequency ablation for the primary efficacy end point of first documented clinical failure.
(Nature Reviews Cardiology, )

ILC3-autonomous Ret ablation led to decreased innate interleukin-22 (IL-22), impaired epithelial reactivity, dysbiosis and increased susceptibility to bowel inflammation and infection.
(Nature, )

A team of researchers has developed a new experimental Meteoric Ablation Simulator (MASI) that can help answer questions about cosmic dust and how it impacts Earth and everything on it.
(Science Daily - News, )

Atrial fibrillation (AF) is common among patients with mitral valve disease, and surgical ablation of AF is often performed in these patients when they are undergoing their valve surgery.
(Nature Reviews Cardiology, )

In this paper, we provide a detailed protocol for a model of long bone mechanical marrow ablation in the rodent, including surgical procedure, anesthesia, and pre- and post-operative care.
(BoneKEy Reports, )

Charlotte Aston, 23, of Brixham, Devon, had to undergo laser ablation heart surgery to correct her irregular heartbeat, which doctors said was due to drinking one can of energy drink a day.
(Daily Mail - Health, )

Lineage ablation of SOX2-expressing cells within primary benign and malignant SCCs leads to tumour regression, consistent with the critical role of SOX2-expressing cells in tumour maintenance.
(Nature, )

Radiofrequency ablation (RFA) and stereotactic body radiotherapy (SBRT) are two of the treatment options available for these patients, and both are generally associated with positive outcomes.
(Nature Reviews Clinical Oncology, )

Our findings suggest that, over these three decades, hydrodynamic coupling in this section of the ablation zone resulted in a net slowdown of ice motion (not a speed-up, as previously postulated).
(Nature, )

They found that ablation of Tlr2 or myeloid differentiation primary response gene 88 (Myd88; which functions downstream of TLR2) reduced inflammation-induced tumorigenesis of intestinal epithelium.
(Nature Reviews Cancer, )

Liu et al . show that apelin-driven expression of Cre recombinase in mice can be used for labelling of, or gene ablation in, sprouting but not quiescent ECs in pathologies characterized by hypoxia.
(Nature Communications, )

However, the use of more powerful lasers to increase the ablation rate results in unwanted effects such as shielding, saturation and collateral damage from heat accumulation at higher laser powers.
(Nature, )

Transient atrial tachyarrhythmias occur frequently in the first few months after ablation for atrial fibrillation (AF), and this phenomenon is associated with later recurrence of atrial arrhythmias.
(Nature Reviews Cardiology, )

S. Typhimurium used galactarate and glucarate within the gut lumen of streptomycin pre-treated mice, and genetic ablation of the respective catabolic pathways reduced S. Typhimurium competitiveness.
(Nature, )

Historically, oral vitamin K antagonist (VKA) treatment has been interrupted in patients with atrial fibrillation (AF) who are undergoing catheter ablation, and heparin has been used to bridge the gap.
(Nature Reviews Cardiology, )

Genetic ablation of EF4 in mice leads to male sterility due to mitochondrial translation defects, which can be compensated for in somatic tissues by mTOR-mediated upregulation of cytoplasmic translation.
(Nature Structural & Molecular Biology, )

Secondary analysis suggested that cryoablation had advantages over radiofrequency ablation in terms of rehospitalizations and repeat procedures; however, the validity of these results must be questioned.
(Nature Reviews Cardiology, )

Ablation of Ret leads to impaired survival and reduced numbers of haematopoietic stem cells with normal differentiation potential, but loss of cell-autonomous stress response and reconstitution potential.
(Nature, )

New research in mice shows that following β-cell ablation two distinct age-dependent mechanisms exist within the pancreatic islets to replenish insulin-producing cells from cells of a non-β-cell origin.
(Nature Reviews Endocrinology, )

A better understanding of ipsilateral neural structures and networks for verbal memory could improve selectivity of surgical ablation, thereby holding promise for seizure-freedom without memory impairment.
(Nature Reviews Neurology, )

Importantly, pharmacological inhibition of MEK and ERK markedly improves insulin resistance in both obese wild-type and ob/ob mice, and also completely reverses the deleterious effects of the Cdk5 ablation.
(Nature, )

Using a combination of cell ablation, lineage tracing and signalling pathway modulation, we show that airway basal stem/progenitor cells continuously supply a Notch ligand to their daughter secretory cells.
(Nature, )

By contrast, naive HEK293T cells and HEK293T cells expressing several other GPCRs did not react to the flexible tail, and ablation of Gpr126 from SW10 cells abolished the flexible tail-induced cAMP response.
(Nature, )

Ablation of cancer stem cells in established glioblastomas in mice by knockout of the nuclear receptor tailless (Tlx) has therapeutic benefit, and TLX may have a similar role in human glioblastoma stem cells.
(Nature Reviews Cancer, )

Here, Luckman et al . use satellite data to derive frontal ablation rates for dynamically contrasting Svalbard glaciers, and show that frontal ablation rate varies primarily with sub-surface ocean temperature.
(Nature Communications, )

Incomplete ablation of renal nerves owing to the presence of accessory renal arteries that are too small for denervation might partly account for persistent hypertension after renal denervation say researchers.
(Nature Reviews Nephrology, )

When biomaterials such as tissue engineering scaffolds or metal implants are placed in the medullary cavity after marrow ablation, end points relevant to tissue engineering and implant fixation can also be analyzed.
(BoneKEy Reports, )

Here, Lant et al. shed light on the mechanism of CCM-3 function in C. elegans, and show that CCM-3 ablation leads to defects in excretory canal extension and the formation of cysts reminiscent of human malformations.
(Nature Communications, )

Upon tamoxifen-induced mutp53 ablation, allotransplanted and autochthonous tumours curb their growth, thus extending animal survival by 37%, and advanced tumours undergo apoptosis and tumour regression or stagnation.
(Nature, )

Here authors show that Tsc1 ablation in oligodendrocyte lineage activates ER stress and apoptotic programs in mice, and that enhancing PERK-eIF2α signalling partially rescues the myelination defects in Tsc1 mutants.
(Nature Communications, )

Here, the authors report a mass spectral technique based on extreme ultraviolet laser ablation that allows three-dimensional imaging of chemical composition in addition to giving highly sensitive nanoscale resolution.
(Nature Communications, )

Many of the techniques used to date rocks on Earth are not practical in spaceflight, but a technique called laser ablation resonance ionization mass spectrometry can avoid the need for sophisticated sample preparation.
(Science Daily - News, )

Here Peng et al. use temporally controlled ablation of monocytes and microglia in mice to show that these cells work together to initiate neuropathic-pain like behaviour, but are less important in the maintenance phase.
(Nature Communications, )

The epicardium vigorously regenerates after its ablation, through proliferation and migration of spared epicardial cells as a sheet to cover the exposed ventricular surface in a wave from the chamber base towards its apex.
(Nature, )

Despite remarkable advances in antiarrhythmic drugs, ablation procedures, and stroke-prevention strategies, atrial fibrillation (AF) remains an important cause of death and disability in middle-aged and elderly individuals.
(Nature Reviews Cardiology, )

Lecuit and colleagues use live imaging and laser ablation approaches to show that germ-band extension of the Drosophila embryo is associated with new junction growth, which is dependent on both tissue-level and local forces.
(Nature Cell Biology, )

Among other features, the 2014 Guideline for the Management of Patients With Atrial Fibrillation incorporates important new information about the new oral anticoagulants and catheter ablation for the treatment of AF symptoms.
(Forbes - Business, )

Chai and colleagues report that Gli1-expressing cells within the mouse cranial suture mesenchyme contribute to all cranial bones, and their ablation leads to impaired skull injury repair, skull growth arrest and osteoporosis.
(Nature Cell Biology, )

In the absence of new drug developments, clinical intervention procedures such as renal nerve ablation and baroreflex activation therapy have dominated the research, but the results have not yet fulfilled the great expectations.
(Nature Reviews Cardiology, )

We demonstrate that a subpopulation of dormant tumour cells surviving oncogene ablation (surviving cells) and responsible for tumour relapse has features of cancer stem cells and relies on oxidative phosphorylation for survival.
(Nature, )

The 1-year outcomes of this large, multinational study highlight variation in the concomitant use of antiarrhythmic drugs, and the need for rigorous clinical follow-up after ablation, with extended electrocardiographic monitoring.
(Nature Reviews Cardiology, )

Since removal of crust by ablation would also remove the heat-producing elements—potassium, uranium and thorium—such removal would make it extremely difficult to balance terrestrial heat production with the observed heat flow.
(Nature, )

Using a chaperone auto-inhibition strategy, we achieved rapid, reversible ablation of HSP101 function, resulting in a nearly complete block in export with substrates accumulating in the vacuole in both asexual and sexual parasites.
(Nature, )

Here the authors show that prostaglandin E2 promotes Th17 differentiation by activating transcription of IL-17 by CREB/CRTC2 complex, and that ablation of CRTC2 prevents Th17 differentiation and multiple sclerosis in a mouse model.
(Nature Communications, )

Here the authors present a multimodal endoscope with theranostic nanoparticles that integrates fluorescence-based mapping, electrical impedance, pH and temperature monitoring, RF ablation and localized phototherapy or chemotherapy.
(Nature Communications, )

In mice, an early ablation of myelinating oligodendrocytes can trigger a secondary, CD4+ T cell-associated demyelination 30 weeks later, suggesting a possible mechanism for the onset of demyelinating diseases such as multiple sclerosis.
(Nature Reviews Neuroscience, )

Inhibiting cholesterol esterification in T cells by genetic ablation or pharmacological inhibition of ACAT1, a key cholesterol esterification enzyme, led to potentiated effector function and enhanced proliferation of CD8+ but not CD4+ T cells.
(Nature, )

Recent data implicate a discrete population of cells within the cervical squamocolumnar junction in the pathogenesis of cervical precancerous lesions, indicating that ablation of these cells might reduce the rate of cervical cancer in high-risk populations.
(Nature Reviews Clinical Oncology, )

Ablation of these cells inhibits apical fold formation, prolongs AER activity and increases the amount of fin bud mesenchyme, suggesting that these cells could provide the timing mechanism proposed in Thorogood’s clock model of the fin-to-limb transition.
(Nature, )

They show that migration of connective tissue fibroblasts derived from the pleuroperitoneal folds controls diaphragm morphogenesis and that mosaic ablation of Gata4 in this cell population results in defects resembling human congenital diaphragmatic hernias.
(Nature Genetics, )

Radiofrequency catheter ablation reduces the rate of atrial fibrillation (AF) recurrence to a greater extent than antiarrhythmic drug therapy when used as first-line therapy for paroxysmal AF, according to the results of the randomized, multicentre RAAFT-2 trial.
(Nature Reviews Cardiology, )

Acute ablation of T cell antigen receptors (TCRs) in regulatory T cells (Treg cells) impairs the suppressive activity of these cells, even though they retain expression of Foxp3 and CD25. TCR signaling imparts a critical role in the suppressive function of Treg cells.
(Nature Immunology, )

Advances reported in 2015 will help to guide physicians in the use of therapeutic approaches ranging from established pharmaceutical agents through ablation of arrhythmic sources to novel uses of implanted devices for life-threatening bradyarrhythmias and tachyarrhythmias.
(Nature Reviews Cardiology, )

In patients with ischaemic cardiomyopathy, an implanted cardioverter–defibrillator, and recurrent ventricular tachycardia despite the use of antiarrhythmic drugs, catheter ablation is more effective than escalated drug therapy at preventing death or recurrent tachycardia.
(Nature Reviews Cardiology, )

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