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Examples of acidosis


7 examples:

Acidosis is algogenic for nociceptive sensory neurons.
(BoneKEy Reports, )

In hypoxic conditions, cells depend on anaerobic respiration, which results in extracellular acidosis.
(Nature Communications, )

Debate exists regarding the safety of metformin and the risk of metformin-associated lactic acidosis, particularly in the setting of kidney dysfunction.
(Nature Reviews Nephrology, )

Despite its strong safety profile, the FDA has long recommended that metformin not be prescribed to patients with mild to moderate kidney disease due to the risk of lactic acidosis, a potentially serious condition.
(Science Daily - News, )

Data from two studies examining the interplay between metformin, acute kidney injury, and complications including lactic acidosis suggest that metformin should be used conservatively in patients with kidney dysfunction.
(Nature Reviews Nephrology, )

Khacho et al. find that acidosis serves a protective function, enhancing mitochondrial respiratory capacity and sustaining ATP synthesis despite limited oxygen availability, by both promoting mitochondrial fusion and inhibiting fission.
(Nature Communications, )

Chronic acidosis has previously been shown to induce an increase in acid-secreting α-intercalated cells and a decrease in HCO3-secreting β-intercalated cells in the cortical collecting duct (CCD), resulting in a net increase in CCD acid secretion.
(Nature Reviews Nephrology, )

Other examples

See also examples for metabolic acidosis.

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