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Header of actomyosin

Examples of actomyosin

Sentences

25 examples:

The stability of epithelial adherens junctions depends on tension generated by actomyosin contractility.
(Nature Communications, )

Closure of epithelial gaps such as wounds is thought to involve contraction of an actomyosin ‘purse-string’.
(Nature Communications, )

The structure reveals details of the actomyosin interface, which is mainly stabilized by hydrophobic interactions.
(Nature, )

Hyman, Muller and colleagues characterize how mitotic rounding forces relate to the dynamics of the actomyosin cortex.
(Nature Cell Biology, )

Epithelial sheet migration proceeds via a series of actomyosin contractions, called pulses, that are stabilized, or ratcheted.
(Nature Communications, )

Here, using electron cryomicroscopy, we present the structure of a human rigor actomyosin complex at an average resolution of 3.9 Å.
(Nature, )

The mechanical regulation of cadherin adhesions is now shown to involve myosin-dependent tension in the cortical actomyosin cytoskeleton.
(Nature Cell Biology, )

Ect2 then signals to the overlying cortex to promote the assembly and constriction of an actomyosin ring between segregating chromosomes.
(Nature, )

The difficulty of obtaining diffracting crystals, however, has prevented structure determination by crystallography of actomyosin complexes.
(Nature, )

Actomyosin contractility is regulated by phosphorylation of myosin regulatory light chain; much of the work in this area has focused on the kinase.
(Nature Communications, )

Epithelial wound closure proceeds through both crawling into the wound and by constricting an actomyosin cable in a so-called purse-string mechanism.
(Nature Communications, )

We show in mouse cells that PDPN induces actomyosin contractility in FRCs via activation of RhoA/C and downstream Rho-associated protein kinase (ROCK).
(Nature, )

This coordination is achieved by the recruitment of an actomyosin regulator, Ect2, to overlapping microtubules at the centre of the elongating anaphase spindle.
(Nature, )

Engagement by CLEC-2 causes PDPN clustering and rapidly uncouples PDPN from RhoA/C activation, relaxing the actomyosin cytoskeleton and permitting FRC stretching.
(Nature, )

They show that Dia and Rok regulate the formation of an actomyosin coat around the vesicle, with a contractile myosin II case-like structure driving content release.
(Nature Cell Biology, )

Here the authors use Drosophila follicle cells and modelling to show that the phosphatase subunit Flapwing controls the initiation and dynamics of actomyosin oscillations.
(Nature Communications, )

Biochemical characterization of mechanosensitive proteins is achieved in a protocol for forming actomyosin cables between protein-coated discs on a micropatterned glass coverslip.
(Nature Protocols, )

Actomyosin networks undergo cycles of assembly and disassembly (pulses) to cause cell deformations alternating with steps of stabilization to result in irreversible shape changes.
(Nature, )

In mice, oriented cell division, apicobasal polarity and actomyosin contractility are thought to contribute to the formation of the ICM. However, how these processes work together remains unclear.
(Nature, )

By measuring surface tensions in developing mouse embryos, Maître and colleagues show that compaction of the blastomere stage embryo is driven by downregulation of actomyosin at cell–cell contacts.
(Nature Cell Biology, )

Sahai and colleagues delineate a pathway through which components of the STRIPAK complex promote amoeboid cancer cell migration by regulating the linkage of the actomyosin network to the plasma membrane.
(Nature Cell Biology, )

Here Campos et al . show that the scaffold protein Alix interacts with F-actin, the Par complex and ZO-1 to ensure the formation and maintenance of the actomyosin tight junction complex in choroid plexus epithelium.
(Nature Communications, )

Using live imaging of zebrafish angiogenesis, Gerhardt and colleagues observe blood-flow-regulated inverse membrane blebbing during lumen expansion, and show that actomyosin contractility is needed for both bleb retraction and lumen formation.
(Nature Cell Biology, )

, transmitted by the remodelling of the actomyosin cytoskeleton and concomitant depletion of the nuclear actin pool, is shown to induce silencing of differentiation genes in epidermal stem cells, linking mechanical cues to the genetic regulation of cell fate.
(Nature Reviews Molecular Cell Biology, )

Mechanical strain, transmitted by the remodelling of the actomyosin cytoskeleton and concomitant depletion of the nuclear actin pool, is shown to induce silencing of differentiation genes in epidermal stem cells, linking mechanical cues to the genetic regulation of cell fate.
(Nature Reviews Molecular Cell Biology, )

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