For all your dictionary needs!
Tip. You can look up words, expressions, names, titles...
Header of adenocarcinoma

Examples of adenocarcinoma

Sentence with the noun adenocarcinoma

1 example:

Transcriptional profiling of Kras-driven early lesions—aimed at identifying founder events—reveals DDR1 as a therapeutic target relevant to adenocarcinoma.
(Nature Medicine, )

Other sentences

83 examples:

Researchers have identified a subtype of human adenocarcinoma.
(Science Daily - News, )

Adenocarcinoma of the lung is the leading cause of cancer death worldwide.
(Nature, )

Oesophageal adenocarcinoma is often treated with chemotherapy before surgery.
(Nature Communications, )

Targeted therapies have improved patient survival in metastatic lung adenocarcinoma.
(BoneKEy Reports, )

Atypical adenomatous hyperplasia is thought to be a precursor lesion for lung adenocarcinoma.
(Nature Communications, )

Perera et al. investigated the high levels of autophagy in pancreatic ductal adenocarcinoma (PDAC).
(Nature Reviews Cancer, )

They identify two pathways by which Barrett's esophagus can develop into esophageal adenocarcinoma.
(Nature Genetics, )

Lung adenocarcinoma (ADC) and squamous cell carcinoma (SCC) are the two major subtypes of lung cancer.
(Nature Communications, )

Therapeutic targeting of KRAS-mutant lung adenocarcinoma represents a major goal of clinical oncology.
(Nature, )

The majority of colorectal cancers (CRCs) are classified as adenocarcinoma not otherwise specified (AC).
(Nature Reviews Clinical Oncology, )

Resistance to receptor tyrosine kinase inhibitors is a major obstacle in treatment of lung adenocarcinoma.
(Nature Communications, )

The survival duration of patients with pancreatic adenocarcinoma (PDAC) is among the lowest of all cancers.
(Nature Reviews Clinical Oncology, )

Surgeon Eric Lim says non-smokers are just as likely as smokers to get a type of cancer called adenocarcinoma.
(Daily Mail - News, )

Barrett’s oesophagus is a precancerous intestinal metaplasia that can progress to oesophageal adenocarcinoma.
(Nature Communications, )

Here the authors show that STAT3 acts as a tumour suppressor in a mouse model of Kras-driven lung adenocarcinoma.
(Nature Communications, )

A new study supports the hypothesis that lung cancer, particularly adenocarcinoma, may spread through the airways.
(Science Daily - News, )

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an extensive stromal component that hinders treatment.
(Nature Medicine, )

Diagnosis of pancreatic ductal adenocarcinoma (PDA) has poor long-term survival rates with limited therapy options.
(Nature Communications, )

Takano et al. show that in pancreatic ductal adenocarcinoma (PDAC), both isoforms have distinct roles in metastasis.
(Nature Reviews Cancer, )

By the time she was diagnosed with a rare and aggressive form of cancer called adenocarcinoma, it was already terminal.
(Tech Times - Health, )

Expression of ADAM8, a metalloprotease disintegrin, correlates with worse prognosis in pancreatic adenocarcinoma (PDAC).
(Nature Communications, )

The genetic determinants of progression from premalignant Barrett's esophagus to esophageal adenocarcinoma are not known.
(Nature Genetics, )

Pancreatic ductal adenocarcinoma (PDA) is the most common form of pancreatic cancer and has a particularly low survival rate.
(Nature Reviews Drug Discovery, )

Despite lung adenocarcinoma having a high global mortality, the genetic mutations present in Asian patients are uncharacterized.
(Nature Communications, )

Pancreatic ductal adenocarcinoma (hereafter referred to as pancreatic cancer) is a particularly robust example of this phenomenon.
(Nature Reviews Cancer, )

The pathogenesis of pancreatic ductal adenocarcinoma (PDA) requires high levels of autophagy, a conserved self-degradative process.
(Nature, )

The authors find that alterations in retrotransposition can occur at different stages in the evolution of pancreatic adenocarcinoma.
(Nature Medicine, )

Demi Wright, from Colchester, started suffering pains in her side in November last year, but did not know she had terminal adenocarcinoma.
(Daily Mail - Health, )

No standard-of-care therapy exists for patients with metastatic pancreatic adenocarcinoma who have progressed on gemcitabine-based therapy.
(Nature Reviews Clinical Oncology, )

Another type of programmed cell death is necroptosis (programmed necrosis), but its role in pancreatic ductal adenocarcinoma (PDA) is unclear.
(Nature, )

Pancreatic ductal adenocarcinoma (PDAC), the most common type of malignancy of the pancreas, is extremely aggressive and very difficult to treat.
(Science Daily - News, )

Mutations in the serine/threonine kinase ataxia teleangiectasia mutated (ATM) have been linked to pancreatic ductal adenocarcinoma (PDAC) cohorts.
(Nature Communications, )

Rebecca Fitzgerald and colleagues report whole-genome sequence analyses of 23 paired samples of Barrett's esophagus and esophageal adenocarcinoma.
(Nature Genetics, )

In patient samples of lung adenocarcinoma, 3 percent were found to have HER2 amplification and another 3 percent were found to have HER2 mutation.
(Science Daily - News, )

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease characterized by an intense fibrotic stromal response and deregulated metabolism.
(Nature, )

Adam Bass, Gad Getz, Scott Carter and colleagues report the whole-exome sequences of 25 pairs of esophageal adenocarcinoma and Barrett's esophagus.
(Nature Genetics, )

Pancreatic ductal adenocarcinoma, the most common of pancreatic cancers, is extraordinarily lethal, with a five-year survival rate of just 6 percent.
(Science Daily - News, )

Their research is the first showing that lung adenocarcinoma can affect the body clock's sway over lipid metabolism and sensitivity to insulin and glucose.
(Science Daily - News, )

The management of pancreatic adenocarcinoma (PDAC) is influenced by the presence of a stromal compartment in tumours—and this component is a hallmark of PDAC.
(Nature Reviews Clinical Oncology, )

Here, the authors uncover a growth suppressive role for ZEB1 in EGFR mutant lung adenocarcinoma, thus elucidating the context dependent function of this protein.
(Nature Communications, )

Jorge Reis-Filho and colleagues identify recurrent mutations in PRKD1 in 73% of polymorphous low-grade adenocarcinoma, a malignant tumor of the minor salivary glands.
(Nature Genetics, )

Their analyses of the clonal architecture of these lesions shows that copy number increases and heterogeneity persists during development of esophageal adenocarcinoma.
(Nature Genetics, )

Loss-of-function mutations in tumour suppressor genes are associated with oesophageal adenocarcinoma (EAC), but the mechanisms underlying EAC development remain unclear.
(Nature Communications, )

Pancreatic ductal adenocarcinoma (PDAC) accounts for the vast majority (90%) of all pancreatic cancers, and remains a disease with a very poor prognosis and high morbidity.
(Nature Reviews Clinical Oncology, )

Intrinsic resistance to chemotherapy in pancreatic ductal adenocarcinoma (PDA) has been attributed to stromal components, such as activated pancreatic stellate cells (PSCs).
(Nature Reviews Cancer, )

Mazur et al. investigate the potential of targeting the bromodomain and extra-terminal (BET) protein family of chromatin regulators in pancreatic ductal adenocarcinoma (PDAC).
(Nature Reviews Drug Discovery, )

Matthew Meyerson, Ramaswamy Govindan and colleagues examine the exome sequences and copy number profiles of 660 lung adenocarcinoma and 484 lung squamous cell carcinoma tumors.
(Nature Genetics, )

Diagnosis of pancreatic ductal adenocarcinoma (PDAC) is associated with a dismal prognosis despite current best therapies; therefore new treatment strategies are urgently required.
(Nature, )

The researchers successfully used the new 'Cas9 mouse' model to edit multiple genes in a variety of cell types, and to model lung adenocarcinoma, one of the most lethal human cancers.
(Science Daily - News, )

DeNardo and colleagues report that inhibiting focal adhesion kinase in pancreatic ductal adenocarcinoma (PDAC) in mice reduces fibrosis and improves the efficacy of tumor immunotherapy.
(Nature Medicine, )

Scientists have characterized structurally abnormal genes in esophageal adenocarcinoma, the findings of which could pave way for developing new biomarkers in this fatal disease, they say.
(Science Daily - News, )

Using mouse models for pancreatic ductal adenocarcinoma and lung adenocarcinoma, we found that abrogating SMYD3 catalytic activity inhibits tumour development in response to oncogenic Ras.
(Nature, )

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers in western countries, with a median survival of 6 months and an extremely low percentage of long-term surviving patients.
(Nature, )

By separating genomics data from the predicted cellular source (such as stromal cell versus pancreatic tumour cell), Moffitt et al. have identified subtypes of pancreatic adenocarcinoma (PDAC).
(Nature Reviews Cancer, )

Jen Jen Yeh and colleagues apply statistical methods to separate tumor, stroma and normal tissue gene expression signatures from pancreatic ductal adenocarcinoma expression profiling data sets.
(Nature Genetics, )

Here we show that targeted therapy with BRAF, ALK or EGFR kinase inhibitors induces a complex network of secreted signals in drug-stressed human and mouse melanoma and human lung adenocarcinoma cells.
(Nature, )

The methods used to anesthetize prostate cancer patients and control pain when their prostate glands are surgically removed for adenocarcinoma may affect their long-term cancer outcomes, a study found.
(Science Daily - News, )

The aggressive nature of pancreatic adenocarcinoma, its difficulty in being detected at early stages, and its propensity to develop resistance to chemotherapy makes of this cancer one of the deadliest types.
(Nature Reviews Clinical Oncology, )

An intention-to-treat analysis has shown that timing and duration of adjuvant chemotherapy can be optimized to allow full postoperative recovery for patients undergoing resection for pancreatic adenocarcinoma.
(Nature Reviews Clinical Oncology, )

In this study, the authors isolate and characterize human Barrett’s stem cells and identify a specific genomic pedigree that supports the potential role of these cells as precursors of oesophageal adenocarcinoma.
(Nature Communications, )

Expression of HNF1A and KRT81 stratifies pancreatic ductal adenocarcinoma tumors into different subtypes, and expression of cytochrome P450 3A5 mediates basal and/or drug-induced therapy resistance in each subtype.
(Nature Medicine, )

Because SMAD4, a mediator of TGFβ signalling, is frequently inactivated in pancreatic ductal adenocarcinoma (PDAC), David et al. used this cancer type to investigate the dichotomous role of TGFβ in tumorigenesis.
(Nature Reviews Cancer, )

Adenocarcinoma histology, female sex, never-smoking status, and Asian ethnicity have been considered the most important factors associated with EGFR mutations in non-small cell lung cancer and response to EGFR inhibitors.
(Science Daily - News, )

Genome-wide DNA methylation analysis of metastatic biopsies from patients with castration-resistant prostate cancer reveals marked epigenetic differences between samples with adenocarcinoma and neuroendocrine histologies.
(Nature Medicine, )

Pancreatic intraepithelial neoplasia is a pre-malignant lesion that can progress to pancreatic ductal adenocarcinoma, a highly lethal malignancy marked by its late stage at clinical presentation and profound drug resistance.
(Nature, )

Steele et al. found that C-X-C chemokine receptor type 2 (CXCR2) expression in neutrophils and myeloid-derived suppressor cells (MDSCs) at tumour borders correlates with poor prognosis in pancreatic ductal adenocarcinoma (PDAC).
(Nature Reviews Cancer, )

This population could be effectively targeted by deletion of either Msi1 or Msi2, which led to a striking defect in the progression of pancreatic intraepithelial neoplasia to adenocarcinoma and an improvement in overall survival.
(Nature, )

A paper in Nature identifies glypican 1 as a marker of circulating exosomes derived from pancreatic ductal adenocarcinoma (and from some breast cancers) that could be an effective biomarker for early diagnosis and treatment monitoring.
(Nature Reviews Cancer, )

Jiang et al. show that inhibition of focal adhesion kinase (FAK) reduces immunosuppression and fibrosis in pancreatic ductal adenocarcinoma (PDAC) and can improve the efficacy of both chemotherapy and immunotherapy in PDAC mouse models.
(Nature Reviews Cancer, )

Hebrok and colleagues use mouse models to demonstrate that loss of the chromatin modifier Brg1 cooperates with oncogenic KRas to form lesions resembling intraductal papillary mucinous neoplasia that progress to pancreatic adenocarcinoma.
(Nature Cell Biology, )

Barrett's oesophagus, a condition usually caused by chronic exposure to stomach acid, is a precursor state to the development of oesophageal adenocarcinoma; however, only a small fraction of those with Barrett's oesophagus develop cancer.
(Nature Reviews Clinical Oncology, )

CRISPR/Cas9-mediated repression or deletion of a MYC enhancer in a lung adenocarcinoma cell line with the enhancer amplification results in downregulation of MYC and its target genes and impaired anchorage-independent and clonogenic growth.
(Nature Genetics, )

Two papers published in Nature Genetics have reported whole-genome and whole-exome sequencing of paired Barrett oesophagus and oesophageal adenocarcinoma (EAC) samples, providing some insights into the development of EAC from its precursor lesion.
(Nature Reviews Cancer, )

Trends in Helicobacter pylori and smoking explain a significant proportion of the decline of intestinal-type noncardia gastric adenocarcinoma incidence in US men between 1978 and 2008, and are estimated to continue to contribute to further declines between 2008 and 2040.
(Science Daily - News, )

New genomic and epigenomic data of samples from patients with metastatic castration-resistant prostate cancer (CRPC) suggest that differentiation into neuroendocrine subtypes from adenocarcinoma precursors follows a divergent evolution pattern, characterized by epigenetic modulation.
(Nature Reviews Urology, )

However, the genetic basis for the immune escape has not been fully elucidated, with the exception of elevated PD-L1 expression by gene amplification and utilization of an ectopic promoter by translocation, as reported in Hodgkin and other B-cell lymphomas, as well as stomach adenocarcinoma.
(Nature, )

The UK tops the international league table for a type of gullet (oesophageal) cancer, known as adenocarcinoma, in men, reveals a comprehensive estimate of the total number of new cases around the globe in 2012. Worldwide, men are around four times as likely as women to develop the disease, the findings show.
(Science Daily - News, )

Widely affecting multiple common human cancer types, including adult T-cell leukaemia/lymphoma (27%), diffuse large B-cell lymphoma (8%), and stomach adenocarcinoma (2%), these SVs invariably lead to a marked elevation of aberrant PD-L1 transcripts that are stabilized by truncation of the 3′-untranslated region (UTR).
(Nature, )

Little is known about the molecular biology of two types of appendix tumors, low-grade appendiceal mucinous neoplasm (LAMN) and adenocarcinoma, but both can lead to pseudomyxoma peritonea (PMP), a critical condition in which cancerous cells grow uncontrollably along the wall of the abdomen and can crush digestive organs.
(Science Daily - News, )

Rebecca Fitzgerald and colleagues used genome sequence analyses to study the progression from premalignant Barrett's esophagus to esophageal adenocarcinoma (EAC) and found that the majority of recurrently mutated genes in EAC were also mutated in precursor lesions and that only mutations in TP53 and SMAD4 were stage specific.
(Nature Genetics, )

The BRG1 catalytic subunit of the chromatin remodelling SWI/SNF complex has context-dependent functions during different stages of pancreatic ductal adenocarcinoma development from intraductal papillary mucinous neoplasia, and bromodomain and extraterminal inhibitors might be therapeutically beneficial in this subtype of pancreatic cancer.
(Nature Reviews Cancer, )

Computer-Aided Nodule Assessment and Risk Yield, is a novel software tool that can automatically quantitate adenocarcinoma pulmonary nodule characteristics from non-invasive high resolution computed tomography images and stratify non-small cell lung cancer patients into risk groups that have significantly different disease-free survival outcome.
(Science Daily - News, )

Specifically, we developed Msi reporter mice that allowed image-based tracking of stem cell signals within cancers, revealing that Msi expression rises as pancreatic intraepithelial neoplasia progresses to adenocarcinoma, and that Msi-expressing cells are key drivers of pancreatic cancer: they preferentially harbour the capacity to propagate adenocarcinoma, are enriched in circulating tumour cells, and are markedly drug resistant.
(Nature, )

Other examples

See also examples for adenocarcinomas.

Don't miss the pronunciation examples of adenocarcinoma to learn how to say it correctly!

Share this page

Next...

Go to the thesaurus of adenocarcinoma to find many related words and phrases!


Privacy Policy | Cookies Policy
Keyword Tool | Romanian-English Dictionary