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Examples of Adjuvant

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37 examples:

Current standard treatments include surgical resection, adjuvant chemotherapy and radiotherapy.
(Science Daily - News, )

Vaccine efficacy is enhanced by optimizing the design of polymeric particles for adjuvant and antigen delivery.
(Nature Biotechnology, )

A study has now reported a beneficial impact of adjuvant RRSO in patients with BRCA1 mutations and breast cancer.
(Nature Reviews Clinical Oncology, )

The recently published EORTC 22921 study adds further debate to the merits of adjuvant chemotherapy in this setting.
(Nature Reviews Clinical Oncology, )

Adjuvant chemotherapy for breast cancer is 'gerontogenic,' accelerating the pace of physiologic aging, according to a new study.
(Science Daily - News, )

This information might be useful to assess individual prognosis and stratify patients at risk to systemic adjuvant anti-cancer therapies.
(BoneKEy Reports, )

Several clinical trials have addressed the role of adjuvant chemotherapy following neoadjuvant chemoradiation and surgery for rectal cancer.
(Nature Reviews Clinical Oncology, )

Several clinical trials have investigated the antitumour effect of bisphosphonates when used as adjuvant treatment for early stage breast cancer.
(Nature Reviews Clinical Oncology, )

A biomarker has been identified that predicts which stage II colon cancer patients may benefit from adjuvant chemotherapy to prevent a disease recurrence.
(Science Daily - News, )

The findings show that regardless of socioeconomic status and comorbidities, adjuvant chemotherapy improved survival by approximately 23 percent in stage III STS.
(Science Daily - News, )

A team of scientists has discovered a new drug that inhibits repair: spironolactone, which seems likely to be used in the very short term as an adjuvant to chemotherapy.
(Science Daily - News, )

An ASCO endosement panel has reviewed the 2013 AUA/ASTRO guidelines on adjuvant and salvage radiotherapy after prostatectomy and concluded that they are clear and thorough.
(Nature Reviews Urology, )

Dependent on specific tumor characteristics, radiation, CHT, antibody treatment as well as endocrine treatment have been included into the adjuvant clinical treatment setting.
(BoneKEy Reports, )

Aerobic exercise is no friend to breast tumors, says a new study which suggests that regular physical activity may be a "novel adjuvant treatment" for women with breast cancer.
(Melissa Healy in Los Angeles Times - Science, )

Findings from a federally funded study suggest that patients with locally advanced kidney cancer should not be treated with either adjuvant (post-surgery) sorafenib or sunitinib.
(Science Daily - News, )

In the RADIANT study, no difference in disease-free survival was observed for patients with non-small-cell lung cancer (NSCLC) treated with erlotinib versus placebo in the adjuvant setting.
(Nature Reviews Clinical Oncology, )

Oncotype DX is a 21-gene assay used to help estimate the likelihood of recurrence in women with early-stage breast cancer and, thus, determine those who may or may not benefit from adjuvant chemotherapy.
(Science Daily - News, )

Although 5-fluorouracil (5-FU), leucovorin and oxaliplatin (FOLFOX) is a standard treatment for colon cancer, this regimen has never been tested in the adjuvant setting for locally advanced rectal cancer.
(Nature Reviews Clinical Oncology, )

Since studies are lacking, it remains unclear whether certain patients have a benefit if the decision for or against adjuvant chemotherapy is based on the concentration of uPA and PAI-1, a new report states.
(Science Daily - News, )

An intention-to-treat analysis has shown that timing and duration of adjuvant chemotherapy can be optimized to allow full postoperative recovery for patients undergoing resection for pancreatic adenocarcinoma.
(Nature Reviews Clinical Oncology, )

The first retrospective analysis of adjuvant chemotherapy's impact on overall survival in patients with stage III soft tissue sarcomas (STS) has been conducted, adjusted for socioeconomic status and other variables.
(Science Daily - News, )

Therefore, β-blockers or therapies normalizing sympathetic tone might be beneficial as early adjuvant therapies to limit skeletal metastases and growth and eventually to improve prognosis in patients with breast cancers.
(BoneKEy Reports, )

This update includes recommendations for screening, surgery, adjuvant chemotherapy and radiotherapy, treatment of locally advanced and metastatic disease as well as new data on patient preferences and geriatric assessment.
(Science Daily - News, )

Progress in prevention and early detection, and the use of chemotherapy after surgery (adjuvant chemotherapy), have achieved significantly increase survival in this disease in the last ten years, but much remains to be done.
(Science Daily - News, )

Based on the results of EORTC trial 18071, the FDA expanded the approval of Yervoy (ipilimumab) in melanoma to include adjuvant treatment of patients with stage 3 melanoma at high risk of recurrence following complete resection.
(Science Daily - News, )

Here, the authors describe an adjuvant strategy using micro-fractional laser treatment combined with a topical cream containing a TLR 7 ligand that can enhance the immune response to intradermal vaccination with transient, constrained local inflammation.
(Nature Communications, )

The EXPERT-C phase II trial in patients with operable high-risk rectal cancer examined adding weekly cetuximab to a regimen of neoadjuvant capecitabine and oxaliplatin (CAPOX), followed by chemoradiotherapy with capecitabine, surgery, and adjuvant CAPOX.
(Nature Reviews Clinical Oncology, )

A minimal synthetic variant of the saponin natural product QS-21 has been developed as a potent, non-toxic adjuvant, enabling dissection of structural requirements in the triterpene domain and in vivo biodistribution studies to probe mechanisms of action.
(Nature Chemistry, )

In 2015, academic-led trials provided evidence for safe de-escalation of adjuvant treatment in early stage breast cancer and answered important questions related to adjuvant regional irradiation and optimal first-line chemotherapy in advanced-stage disease.
(Nature Reviews Clinical Oncology, )

Long-term results of EORTC trial 22921 with 10.4 years median follow-up show that 5-FU-based adjuvant chemotherapy after preoperative (chemo)-radiotherapy for patients with cT3-resectable T4 M0 rectal cancer does not improve survival or disease-free survival.
(Science Daily - News, )

Here we translate this ‘albumin hitchhiking’ approach to molecular vaccines, through the synthesis of amphiphiles (amph-vaccines) comprising an antigen or adjuvant cargo linked to a lipophilic albumin-binding tail by a solubility-promoting polar polymer chain.
(Nature, )

Adjuvant Ipilimumab significantly improves recurrence-free survival in patients with completely resected stage III melanoma at high risk of disease recurrence, research indicates, but that this treatment was also associated with a high rate of immune-related adverse events.
(Science Daily - News, )

A live attenuated enterotoxigenic Escherichia coli vaccine candidate, given in combination with a novel adjuvant, provided significant protection against disease, new results from a safety and immunogenicity study, which included a challenge phase to test efficacy, indicate.
(Science Daily - News, )

Patients undergoing oncologic liver operations who participated in an enhanced recovery program returned sooner to their normal life function and adjuvant cancer therapies than patients who were treated with a traditional approach to perioperative care, according to a new study.
(Science Daily - News, )

A study assessing the impact of the 21-gene recurrence score assay in routine clinical practice on the use of adjuvant chemotherapy in women with early stage ER-positive breast cancers showed that adjuvant chemotherapy use decreased in high-risk patients, but increased in low-risk patients.
(Nature Reviews Clinical Oncology, )

A recent objective study has demonstrated that the use of adjuvant platinum-based intraperitoneal chemotherapy in patients with small-volume residual advanced-stage ovarian cancer remains limited, despite the publication of several phase III trials demonstrating superior overall survival associated with this approach.
(Nature Reviews Clinical Oncology, )

A retrospective study of 2,044 patients with bladder cancer treated with cystectomy in the Ontario Cancer Registry showed that utilization of adjuvant chemotherapy increased from 19941998 (16%), to 19992003 (18%) and to 20042008 (22%), while utilization of neoadjuvant chemotherapy remained stable (mean rate 4%).
(Nature Reviews Urology, )

Other examples

See also examples for adjuvants, adjuvanted, Adjuvant therapy.

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