Examples of Afferent
Chemogenetic stimulation of these afferent neurons in sated mice markedly activates AgRP neurons and induces intense feeding.
Discovery of these afferent neurons capable of triggering hunger advances understanding of how this intense motivational state is regulated.
However, whether Merkel cells or afferent fibres themselves sense mechanical force is still debated, and the molecular mechanism of mechanotransduction is unknown.
Pinprick response is a longstanding feature of the clinical examination for spinal cord damage, but this test cannot target every afferent pathway in the spinothalamic tract.
(Nature Reviews Neurology, )
In response to signals from afferent TRPV1+ C-fibers, STAT3-dependent upregulation of LCN2 in reactive astrocytes of the spinal dorsal horn amplifies itch signaling in multiple rodent models of atopic and contact dermatitis.
(Nature Medicine, )
See also examples for afferents.
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