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Header of aldosterone

Examples of Aldosterone


8 examples:

The renin–angiotensin–aldosterone system (RAAS) regulates blood pressure homeostasis and vascular injury and repair responses.
(Nature Reviews Endocrinology, )

Hyperkalemia is high potassium in the blood, and may occur as a side effect of taking kidney disease medications called Renin Angiotensin Aldosterone System inhibitors.
(Science Daily - News, )

Unfortunately, this triple renin–angiotensin–aldosterone system blockade was associated with worsening of renal function and increases in cardiac events and mortality.
(Nature Reviews Nephrology, )

Induction of diabetes in wild-type mice has revealed increased levels of angiotensin coverting enzyme 2 (ACE2), which is involved in regulation of the renin–angiotensin–aldosterone system.
(Nature Reviews Nephrology, )

If proven safe and effective for long-term use, these therapies might be administered together with intensive renin–angiotensin–aldosterone blockade to reduce adverse effects and renal and cardiovascular risk.
(Nature Reviews Nephrology, )

But trial investigators and heart failure experts believe it is too early to dismiss hope that spironolactone and other aldosterone antagonists-- including Pfizer's Inspra (eplerenone)-- may eventually be found to work in this population.
(Forbes - Business, )

As decreased tissue oxygenation might contribute to acute and chronic kidney disease (CKD), this tool has been examined in patients with CKD. Indeed, the benefits of renin–angiotensin–aldosterone system inhibitors might be partly conferred by increased oxygenation.
(Nature Reviews Nephrology, )

A late-breaking clinical trial, known as the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist trial, demonstrates that spironolactone did not reduce the primary outcome of cardiovascular death, heart failure hospitalization, nor surviving a cardiac arrest in patients with heart failure and preserved ejection fraction.
(Science Daily - News, )

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