Examples of Amidase
The type VI secretion amidase effector (Tae) proteins are potent bacteriocidal enzymes that degrade the cell wall when delivered into competing bacterial cells by the type VI secretion system.
Here the authors report that the chlamydial amidase, AmiA, which can rescue cell division defects of an E. coli amiA mutant, has dual activity as a penicillin sensitive, lipid II-targetting carboxypeptidase.
(Nature Communications, )
Here we show that tae genes have been transferred to eukaryotes on at least six occasions, and that the resulting domesticated amidase effector (dae) genes have been preserved for hundreds of millions of years through purifying selection.
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