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Examples of Amide


7 examples:

Fatty acid amide hydrolase (FAAH) is a key regulator of endocannabinoid signalling.
(Nature Communications, )

Here we demonstrate that amide carbon–nitrogen bonds can be activated and cleaved using nickel catalysts.
(Nature, )

Amides are known to be poor electrophiles, which is typically attributed to the resonance stability of the amide bond.
(Nature, )

Here, the authors provide experimental evidence for this autoionization process at high pressures, showing the transformation of molecular ammonia into ammonium amide.
(Nature Communications, )

Although amides can readily be cleaved by enzymes such as proteases, it is difficult to selectively break the carbon–nitrogen bond of an amide using synthetic chemistry.
(Nature, )

Our approach employs a simple N-methoxy amide group, which serves as both a directing group and an anionic ligand that promotes the in situ generation of the reactive PdX2 (X = ArCONOMe) species from a Pd(0) source using air as the sole oxidant.
(Nature, )

Our results provide a way to harness amide functional groups as synthetic building blocks and are expected to lead to the further use of amides in the construction of carbon–heteroatom or carbon–carbon bonds using non-precious-metal catalysis.
(Nature, )

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